Efect of Ankaferd Blood Stopper on muscle healing

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dc.authorscopusid56800553700
dc.authorscopusid8727763700
dc.authorscopusid8719368100
dc.authorscopusid55957776700
dc.authorscopusid24490752500
dc.authorscopusid6701728236
dc.contributor.authorUygun, Murat
dc.contributor.authorYavuz, Osman Y.
dc.contributor.authorUraş, Ismail
dc.contributor.authorDuman, Ibrahim G.
dc.contributor.authorHaltaş, Hacer
dc.contributor.authorKömürcü, Mahmut
dc.date.accessioned2024-09-19T15:49:44Z
dc.date.available2024-09-19T15:49:44Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: Ankaferd Blood Stopper (ABS), which is a standardized mixture of herbal extracts obtained from fve plants, has been proven as an efcient hemostatic agent and is still used in emergency situations. It is not known exactly if decreased bleeding has positive or negative efects on muscle healing and fbrosis, so the purpose of this study was to test the efect of ABS on muscle healing and morphology.Methods: A total of 66 outbred Wistar rats were divided into three control and three experimental subgroups. In the experimental groups, ABS was sprayed on the cut surface of the soleus. In the control groups, a saline solution was sprayed on the cut surface of the soleus. Subgroups were euthanized afer 2 weeks, 3 weeks and 4 weeks, respectively. In each subgroup, eight rats were used for the biomechanical study to determine muscle healing and three rats were used for the histopathological investigation.Results: Although muscle strength in the control groups was lower than that of the experimental groups in early weeks, no diferences were found between the control and the experimental groups at 4 weeks.Conclusions: ABS has no negative efect on muscle healing. We also observed that ABS accelerated muscle healing compared to the control group. ABS could be used in hemostasis of open fractures and elective orthopedic surgeries. © 2016. CIMen_US
dc.description.sponsorshipTurgut Özal Universityen_US
dc.identifier.doi10.25011/CIM.V39I6.27526
dc.identifier.endpage191en_US
dc.identifier.issn0147-958X
dc.identifier.issue6en_US
dc.identifier.pmid27917816en_US
dc.identifier.scopus2-s2.0-85047584663en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage187en_US
dc.identifier.urihttps://doi.org/10.25011/CIM.V39I6.27526
dc.identifier.urihttps://hdl.handle.net/20.500.12483/15358
dc.identifier.volume39en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherThe Canadian Society for Clinical Investigationen_US
dc.relation.ispartofClinical and Investigative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnimalsen_US
dc.subjectMuscle, Skeletalen_US
dc.subjectPlant Extractsen_US
dc.subjectRatsen_US
dc.subjectRats, Wistaren_US
dc.subjectWound Healingen_US
dc.subjectWounds, Penetratingen_US
dc.subjectankaferd blood stopperen_US
dc.subjectplant extracten_US
dc.subjectanimalen_US
dc.subjectdrug effectsen_US
dc.subjectmetabolismen_US
dc.subjectpathologyen_US
dc.subjectraten_US
dc.subjectskeletal muscleen_US
dc.subjectWistar raten_US
dc.subjectwound healingen_US
dc.subjectWounds, Penetratingen_US
dc.titleEfect of Ankaferd Blood Stopper on muscle healingen_US
dc.typeArticleen_US

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