Mitral Valve Resistance Correlates More Closely with Left Atrial Deformation than with Conventional Indices of Rheumatic Mitral Stenosis

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dc.authoridTanboga, Ibrahim Halil/0000-0003-4546-9227
dc.contributor.authorKurt, Mustafa
dc.contributor.authorTanboga, Ibrahim Halil
dc.contributor.authorKarakas, Mehmet Fatih
dc.contributor.authorBuyukkaya, Eyup
dc.contributor.authorNacar, Alper Bugra
dc.contributor.authorAkcay, Adnan Burak
dc.contributor.authorAksakal, Enbiya
dc.date.accessioned2024-09-18T21:07:54Z
dc.date.available2024-09-18T21:07:54Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground and aim of the study: The relationship between mitral valve (MV) resistance and left atrial (LA) mechanical function is unknown. Hence, the study aim was to investigate the relationship between LA mechanics and MV resistance, compared to conventional indices such as mitral valve area (MVA) and transmitral gradient, in patients with rheumatic mitral stenosis (MS). Methods: The study population consisted of 73 patients with MS and 30 age- and gender-matched controls. MV resistance was calculated and LA strain parameters were assessed from the apical four-chamber view by speckle tracking echocardiography (LA reservoir strain, LA pump strain, LA strain rate (SR)) in all subjects. Results: The MS group has a markedly higher MV resistance (94 +/- 46 versus 67 +/- 22 dynes.s.cm(-5), p = 0.003) and lower LA reservoir strain (24.5 +/- 7.4% versus 36.6 +/- 3.8%, p <0.001), LA pump strain (12.0 +/- 5.0% versus 17.1 +/- 3.4%, p <0.001) and SR (1.23 +/- 0.33 versus 1.4 +/- 0.29, p = 0.017) values compared to controls. Moreover, both LA reservoir strain and LA pump strain correlated with MV resistance more closely than did MVA and transmitral gradients. Multiple linear regression analysis revealed only MV resistance to be an independent predictor of LA reservoir strain, while MV resistance, indexed left atrial volume and mean gradient were independent predictors of LA pump strain. Conclusion: It can be concluded that, in patients with MS, mitral valve resistance was more closely related to LA mechanics measurements than were conventional indices of MS.en_US
dc.identifier.endpage537en_US
dc.identifier.issn0966-8519
dc.identifier.issue4en_US
dc.identifier.pmid24224416en_US
dc.identifier.startpage532en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14027
dc.identifier.volume22en_US
dc.identifier.wosWOS:000330683000012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherI C R Publishersen_US
dc.relation.ispartofJournal of Heart Valve Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStrainen_US
dc.subjectDeterminantsen_US
dc.subjectPressureen_US
dc.subjectImpacten_US
dc.titleMitral Valve Resistance Correlates More Closely with Left Atrial Deformation than with Conventional Indices of Rheumatic Mitral Stenosisen_US
dc.typeArticleen_US

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