Increased Rates of Coronary Artery Calcium Score in Patients with Non- Functioning Adrenal Incidentaloma

Basit Öğe Kaydı
dc.authoridBEKLER, OZKAN/0000-0002-0031-6457
dc.contributor.authorAkkus, Oguz
dc.contributor.authorAkkus, Gamze
dc.contributor.authorKaypakli, Onur
dc.contributor.authorOzturk, Fatma Keles
dc.contributor.authorGurkan, Eren
dc.contributor.authorBekler, Ozkan
dc.contributor.authorSen, Fatih
dc.date.accessioned2024-09-18T20:52:46Z
dc.date.available2024-09-18T20:52:46Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: We evaluated cardiovascular (CV) risk stratification for nonfunctioning adrenal in-cidentalomas (NFAIs) via the coronary-artery-calcium (CAC) score. Materials and Methods: The participants were patients with NFAI (n = 55). They were compared to patients with chest pain, a low-intermediate Framingham-risk score, and a non-diagnostic tread-mill-exercise test, which served as the control group (n = 49). Subsequently, the NFAI group was subdivided according to a CAC score of <100 Agatston units - mild coronary-artery calcification (n = 40) - and >100 Agatston units - moderate-to-severe calcification (n = 15). Results: Similar rates of traditional risk factors were observed between the NFAI and control groups, and lower low-density lipoprotein cholesterol rates were observed in the NFAI group. The CAC score was significantly higher for the NFAI group than the control group. Glucose, potassi-um, adrenocorticotropic-hormone, and basal-cortisol levels were higher in those with a CAC score of >100. High-density-lipoprotein cholesterol estimated glomerular filtration rate and ejection frac-tion (EF) were higher in those with a CAC score of <100. Adenoma size and location were similar between the groups. Age, EF, and glucose were the most significant variables related to CAC score in patients with NFAI, at >100 Agatston units. Discussion: Patients with a low-intermediate CV risk profile and NFAI have a higher risk of atherosclerosis when compared to patients with a low-intermediate CV risk profile, but no NFAI. Conclusion: In patients with NFAI, CAC score evaluation may be used to predict increased atherosclerosis, especially in patients of an older age with higher glucose and decreased EF.en_US
dc.identifier.doi10.2174/1871530320666200910110337
dc.identifier.endpage1325en_US
dc.identifier.issn1871-5303
dc.identifier.issn2212-3873
dc.identifier.issue7en_US
dc.identifier.pmid32914728en_US
dc.identifier.scopus2-s2.0-85113560924en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1319en_US
dc.identifier.urihttps://doi.org/10.2174/1871530320666200910110337
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11387
dc.identifier.volume21en_US
dc.identifier.wosWOS:000687972400002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofEndocrine Metabolic & Immune Disorders-Drug Targetsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNon-functioning adrenal incidentalomasen_US
dc.subjectcoronary-artery calcificationen_US
dc.subjectcomputed tomographyen_US
dc.subjectagatson scoreen_US
dc.subjectadrenocorticotropic-hormone lipoproteinen_US
dc.titleIncreased Rates of Coronary Artery Calcium Score in Patients with Non- Functioning Adrenal Incidentalomaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu