Comparison of sugammadex and neostigmine-atropine on intraocular pressure and postoperative effects

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dc.authoridHanci, Volkan/0000-0002-2227-194X
dc.authoridhakimoglu, sedat/0000-0002-1556-7996
dc.contributor.authorHakimoglu, Sedat
dc.contributor.authorTuzcu, Kasim
dc.contributor.authorDavarci, Isil
dc.contributor.authorKarcioglu, Murat
dc.contributor.authorTuzcu, Esra Ayhan
dc.contributor.authorHanci, Volkan
dc.contributor.authorAydin, Suzan
dc.date.accessioned2024-09-18T20:19:58Z
dc.date.available2024-09-18T20:19:58Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractDuring surgery, changes in intraocular pressure (IOP) can be observed resulting from several factors, such as airway manipulations and drugs used. We aimed to investigate the effects of sugammadex and neostigmine on IOP, hemodynamic parameters, and complications after extubation. Our study comprised 60 patients, aged 18-65 years, with a risk status of the American Society of Anesthesiologists I-II who underwent arthroscopic surgery under general anesthesia. The patients were randomly assigned into two groups. At the end of the surgery, the neuromuscular block was reversed using neostigmine (50 mu g/kg) plus atropine (15 mu g/kg) in Group 1, and sugammadex (4 mg/kg) in Group 2. Neuromuscular blockade was monitored using acceleromyography and a train-of-four mode of stimulation. IOP was measured before induction and at 30 seconds, 2 minutes, and 10 minutes after extubation. A Tono-Pen XL applanation tonometer was used to measure IOP. This showed that elevation in IOP of patients reversed using sugammadex was similar to that recorded in patients reversed using neostigmine-atropine. When heart rate was compared, there was a significant difference between basal values and those obtained at 30 seconds and 10 minutes after extubation in the neostigmine-atropine group. Extubation time (time from withdrawal of anesthetic gas to extubation) was significantly shorter in the sugammadex group (p = 0.003) than in the neostigmine -atropine group. The postextubation IOP values of the sugammadex group were similar to the neostigmine-atropine group. Extubation time (time from withdrawal of anesthetic gas to extubation) was significantly shorter in the sugammadex group (p = 0.003) than in the neostigmine-atropine group. Copyright (C) 2016, Kaohsiung Medical University. Published by Elsevier Taiwan LLC.en_US
dc.identifier.doi10.1016/j.kjms.2016.01.009
dc.identifier.endpage85en_US
dc.identifier.issn1607-551X
dc.identifier.issue2en_US
dc.identifier.pmid26944326en_US
dc.identifier.scopus2-s2.0-84959373639en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage80en_US
dc.identifier.urihttps://doi.org/10.1016/j.kjms.2016.01.009
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9987
dc.identifier.volume32en_US
dc.identifier.wosWOS:000371329100004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Taiwanen_US
dc.relation.ispartofKaohsiung Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectExtubationen_US
dc.subjectIntraocular pressureen_US
dc.subjectNeostigmineen_US
dc.subjectSugammadexen_US
dc.titleComparison of sugammadex and neostigmine-atropine on intraocular pressure and postoperative effectsen_US
dc.typeArticleen_US

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