PsART-ID inception cohort: clinical characteristics, treatment choices and outcomes of patients with psoriatic arthritis

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dc.authoridAyan, Gizem/0000-0003-1889-9619
dc.authoridGonullu, Emel/0000-0002-6990-4206
dc.authoridDuruoz, Mehmet Tuncay/0000-0003-3584-2788
dc.authoriderden, abdulsamet/0000-0002-8084-2018
dc.authoridkucuksahin, orhan/0000-0003-4530-2304
dc.contributor.authorAyan, Gizem
dc.contributor.authorAydin, Sibel Zehra
dc.contributor.authorKimyon, Gezmis
dc.contributor.authorOzisler, Cem
dc.contributor.authorTinazzi, Ilaria
dc.contributor.authorDogru, Atalay
dc.contributor.authorOmma, Ahmet
dc.date.accessioned2024-09-18T20:55:32Z
dc.date.available2024-09-18T20:55:32Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives. Our aim is to understand clinical characteristics, real-life treatment strategies, outcomes of early PsA patients and determine the differences between the inception and established PsA cohorts. Methods. PsArt-ID (Psoriatic Arthritis- International Database) is a multicentre registry. From that registry, patients with a diagnosis of PsA up to 6 months were classified as the inception cohort (n=388). Two periods were identified for the established cohort: Patients with PsA diagnosis within 5-10 years (n = 328), >= 10 years (n = 326). Demographic, clinical characteristics, treatment strategies, outcomes were determined for the inception cohort and compared with the established cohorts. Results. The mean (S.D.) age of the inception cohort was 44.7 (13.3) and 167/388 (43.0%) of the patients were male. Polyarticular and mono-oligoarticular presentations were comparable in the inception and established cohorts. Axial involvement rate was higher in the cohort of patients with PsA >= 10 years compared with the inception cohort (34.8% vs 27.7%). As well as dactylitis and nail involvement (P = 0.004, P = 0.001 respectively). Both enthesitis, deformity rates were lower in the inception cohort. Overall, 13% of patients in the inception group had a deformity. MTX was the most commonly prescribed treatment for all cohorts with 10.7% of the early PsA patients were given anti-TNF agents after 16 months. Conclusion. The real-life experience in PsA patients showed no significant differences in the disease pattern rates except for the axial involvement. The dactylitis, nail involvement rates had increased significantly after 10 years from the diagnosis and the enthesitis, deformity had an increasing trend over time.en_US
dc.identifier.doi10.1093/rheumatology/keaa663
dc.identifier.endpage1762en_US
dc.identifier.issn1462-0324
dc.identifier.issn1462-0332
dc.identifier.issue4en_US
dc.identifier.pmid33097960en_US
dc.identifier.scopus2-s2.0-85104047298en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1755en_US
dc.identifier.urihttps://doi.org/10.1093/rheumatology/keaa663
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11904
dc.identifier.volume60en_US
dc.identifier.wosWOS:000644544400037en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofRheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpsoriatic arthritisen_US
dc.subjectinception cohorten_US
dc.subjectearly diseaseen_US
dc.titlePsART-ID inception cohort: clinical characteristics, treatment choices and outcomes of patients with psoriatic arthritisen_US
dc.typeArticleen_US

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