Ultrasonographic Assessment of the Distal Femoral Cartilage Thickness in Patients with Homozygous Sickle Cell Disease

dc.contributor.authorYildizgoren, Mustafa Turgut
dc.contributor.authorHelvaci, Mehmet Rami
dc.contributor.authorUstun, Nilgun
dc.contributor.authorOsmanoglu, Kasim
dc.contributor.authorTurhanoglu, Ayse Dicle
dc.date.accessioned2024-09-18T20:20:05Z
dc.date.available2024-09-18T20:20:05Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective. To compare the distal femoral cartilage thickness of patients with sickle cell disease (SCD) with those of healthy subjects using ultrasonography. Methods. The study comprised 30 patients with SCD (16 male, 14 female; mean age, 30.1 years) and 30 age-and sex-matched healthy subjects. Demographic features and medications of the patients were recorded. With the knees held in maximum flexion, the femoral cartilage thickness was measured bilaterally with a 7- to 12-MHz linear probe. Using ultrasonography, 3 midpoint measurements were taken from both knees: lateral femoral condyle (LFC), intercondylar area (ICA), and medial femoral condyle (MFC). Results. Patients with SCD had thinner femoral cartilage thickness values at LFC (P = 0.004), at MFC (P = 0.000), and ICA (P = 0.002) when compared with those of the healthy subjects. Patients with SCD also had lower Hb levels (P = 0.000) levels. Weak positive correlations were determined between Hemoglobin (Hb) levels and ultrasonographic measurements in the SCD group at MFC (r = 0.331, P = 0.010), and ICA (r = 0.289, P = 0.025). Low levels of Hb seem to affect the femoral cartilage thickness. Conclusion. These preliminary findings of decreased femoral cartilage thickness in SCD patients should be complemented with future studies. The possibility of early knee joint degeneration and eventual osteoarthritis in SCD should be kept in mind.en_US
dc.identifier.doi10.1177/1947603515614946
dc.identifier.endpage221en_US
dc.identifier.issn1947-6035
dc.identifier.issn1947-6043
dc.identifier.issue3en_US
dc.identifier.pmid27375836en_US
dc.identifier.scopus2-s2.0-84976384330en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.1177/1947603515614946
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10042
dc.identifier.volume7en_US
dc.identifier.wosWOS:000384334800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofCartilageen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectfemoral cartilage thicknessen_US
dc.subjecthemoglobinen_US
dc.subjectsickle-cell diseaseen_US
dc.subjectultrasounden_US
dc.titleUltrasonographic Assessment of the Distal Femoral Cartilage Thickness in Patients with Homozygous Sickle Cell Diseaseen_US
dc.typeArticleen_US

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