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Öğe Administration of a second dose antivenom in the early period: Is it effective in scorpion stings?(Galenos Yayınevi, 2020) El, Çiğdem; Çelikkaya, Mehmet EminAim: It has been known for years that the toxic effects of scorpion envenomation can be fatal. Scorpion antivenom administration reduces the severity of systemic toxicity and fatal complications resulting from envenomation. In cases where clinical progression is poor, a second dose of antivenom can be applied. We aimed to investigate the effectiveness of a second dose of antivenom in this study. Materials and Methods: One hundred patients between 0-17 years who were followed up due to scorpion stings or poisonings in Hatay Mustafa Kemal University, Faculty of Medicine, Department of Pediatrics between October 2016 and March 2018 were analyzed for age, gender, season, site of scorpion stings, clinical findings, treatment, follow-up steps and the effects of a second dose of antivenom on clinical progression retrospectively. Results: Of the total 100 patients, 45 were female (45%) and 55 were male (55%). The average age of the patients was 3.5 years. Sting locations in order of frequency were as follows; feet, hands, legs, arms, head-neck, genital area. Single dose antivenom was given to 26 patients and a second dose was given to the remaining 74 patients. All patients recovered except two patients who were referred with cardiopulmonary insufficiency and passed away. Conclusion: We observed that early antivenom therapy reduces the risk of developing systemic toxicity and also an administered second dose of antivenom corrects systemic findings. We think that the second dose of antivenom should be applied at the 8th hour especially in pediatric patients with ongoing serious systemic findings and all patients should be observed for at least 24 hours.Öğe Biliyer obstrüksiyon oluşturulmuş sıçanlarda probiyotik kullanımının bakteriyel translokasyon üzerindeki etkileri(Hatay Mustafa Kemal Üniversitesi, 2014) Çelikkaya, Mehmet Emin; Akçora, BülentAmaç: Safra yolları tıkanıklıklarında genellikle gram negatif mikroorganizmalara bağlı gelişen sepsis; ciddi morbidite ve mortalite sebebidir. Probiyotiklerin tıkanma sarılıklarında bakteriyel translokasyonu azalttığına dair deneysel çalısmalar vardır. Bu çalışmanın amacı kombine probiyotik mikroorganizma kullanımının bakteriyel translokasyon yanısıra karaciğer (KC) ve ileum (İL) histolojisi üzerindeki etkilerinin araştırılması idi. Yöntem: Çalışmada her biri 10'ar rat içeren 3 grup oluşturuldu. Grup 1 (Sham grubu), grup 2 (Tıkanma sarılığı), grup 3 (Tıkanma sarılığı+Probiyotik). Deneklere lactobacillus acidophilus, lactobacillus rhamnosus, bifidobacterium bifidum, enterococcus faecium ve bifidobacterium longum içeren solüsyon oral yoldan verildi. 7. günün sonunda mikrobiylojik açıdan değerlendirmek amacıyla mezenterik lenf nodu (MLN), dalak ve portal venden kan örnekleri; Histopatolojik değerlendirme için İL ve KC doku örnekleri; Biyokimyasal inceleme için de kan örnekleri alındı. Bulgular: Kan, dalak ve MLN kültürlerinde grup 2 de % 33.8-58.8 oranında üreme saptanırken grup 3'te %14.3-28.6 oranında üreme saptandı ve bu düşüş istatistiksel olarak anlamlıydı (p˂0.05). KC histolojisinde safra duktus proliferasyonu, KC dejenerasyonu, mikroapse varlığı ve kapsül inflamasyonu bulgularında grup 2 ile grup 3 karşılaştırıldığında grup 2'de anlamlı düzeyde hasarın şiddetli olduğu görüldü (p<0.01). İleal villöz derinlik ve ileal inflamasyon parametreleinde grup 2'de patolojinin grup 3'e göre anlamlı düzeyde şiddetli olduğu görüldü (p<0.05). KC hasarlanmasının belirteçleri olan ALT, ALP, AST değerlerinde de tedavi grubunda (grup 3) anlamlı derecede (p˂0.05) düzelme olduğu saptandı. Sonuç: Safra yolu obstrüksiyonunda kombine probiyotik kullanımının bakteriyel translokasyonu azalttığını, karaciğer ve terminal ileum histolojisinde ortaya çıkan patolojik değişiklikleri hafiflettiğini söyleyebiliriz.Öğe A cause of fever that should be kept in mind in family medicine in settlements where livestock farming is widespread: Brucellosis(Galenos Yayınevi, 2019) El, Çiğdem; Çelikkaya, Mehmet EminAim: In our country, where animal husbandry is widespread, we aimed to examine retrospectively data concerning childhood Brucellosis cases, which are not very high in the literature, which may occur with many variable clinical findings and may cause misdiagnosis and serious complications. Materials and Methods: The data of these patients with the diagnosis of Brucellosis who were treated between October 2016 and October 2018 in a Pediatric Clinic were retrospectively analyzed. For the diagnosis of Brucellosis in patients, the Wright agglutination test with complaints and clinical findings set at the titer being 1/160 or above was used. Results: In our study, the mean age of the patients was 7.4 years (3-15). 52.12% (n=37) were male and 47.88% (n=34) were female. All patients had a risk factor for Brucellosis infection. In 88.7% (n=63) of these patients, consumption of milk and dairy products (precipitates, fresh cheese was not cooked), and 11.3% (n=8) of raw meat (raw meatball) consumption and animal contact history were determined. Conclusion: Although early diagnosis and response to treatment with Brucellosis are very good, late diagnosis and inadequate treatment may cause mortality and morbidity with serious complications. Complaints of fatigue, weight loss and especially joint pain with long term fever should be evaluated by family physicians and pediatricians. The diagnosis of these patients should be kept in mind in the diagnosis of Brucellosis, an endemic disease common in our country.Öğe Clinic entity that should not be forgotten in children with high fever; PFAPA syndrome(İnönü Üniversitesi, 2019) El, Çiğdem; Çelikkaya, Mehmet EminAim: PFAPA syndrome which we thought was not well recognized. The high fever clinic of PFAPA syndrome usually mimics infectious conditions therefore it can lead to unnecessary and costly diagnostic tests and treatments. We evaluated the medical history, clinical findings and outcomes of pediatric patients diagnosed with PFAPA syndrome Material and Methods: In Mustafa Kemal University, Faculty of Medicine, Department of Pediatrics between September of 2016 and 2017, demographics, clinical, laboratory, diagnosis and treatment data of our patients diagnosed with PFAPA syndrome were retrospectively reviewed. Results: 68 patients were studied in our study, of which 27 (39.7%) were females and 41 (6.2%) were males. The mean age at onset of symptoms was 21.7 months. The mean age of diagnosis was 34.9 months. The mean duration between episodes of the disease was 27.05 days and the mean duration of episodes was 4.91 days. Conclusion: PFAPA syndrome which causes unnecessary costly examinations and treatments should be kept in mind in high fever clinic and also medical treatment was found to be effective in patients with PFAPA syndrome.Öğe Çocukta rüptüre akciğer kist hidatiği olgusu(2012) Çelik, Tanju; Akçora, Bülent; Tutanç, Murat; Durgun Yetim, Tülin; Karazincir, Sinem; Akın, Mehmet Mustafa; Çelikkaya, Mehmet Emin; Kurtoğlu, AhmetABSTRACT Hydatid cyst (HD), a very common disease in the world, is often transmitted to humans through dog feces. HD is especially common in countries where agriculture and animal husbandry is prevalent. HD is caused by Echinococcus granulosus. The clinic course of HD usually features settling in the liver and lungs. Lung involvement with chest pain, cough, shortness of breath can cause non specific symptoms such as fever and hemoptysis. Diagnostic interventions for HD include chest X-ray tomography, and physical examination. Although the treatment options of HD vary according to the clinical findings of the patients, the primary treatment may be considered as surgery. The most frequently applied methods of surgical treatment are cystectomy and capitonnage. Medical treatment is usually warranted for complicated cases, including the patients with multiple and unresectable lesions, patients who refuse surgery and the patients who cannot tolerate surgery. Treatment with albendazole and its derivatives are used. In this case report, we present a child with primary complaints of cough, chest pain, dyspnea, fatigue and fever who was latterly diagnosed with lung HD.(Turkiye Parazitol Derg 2012; 36: 45-7)Öğe Comparative results after transabdominal Duhamel and Boley procedures in Hirschsprung disease(Logos Medical Publishing, 2019) Çelikkaya, Mehmet Emin; Atici, Ahmet; El, Çi?dem; Urfali, Senem; Akçora, BülentObjective: Hirschsprung Disease (HD) is a neurocristopathy resulting from the migration failure of neural crest cells during intestinal development. It results in aganglionic colon and causes a functional constipation in children. We aimed to compare functional outcomes such as voluntary bowel movements, encopresis and constipation in patients with HD following Boley and Duhamel procedures. Method: Patients who underwent pull through procedures using Boley or Duhamel methods were included in the study. All patients underwent a three-stage operation (opening of the ostomy, definitive operation and closure of the ostomy). Krickenbeck criteria were used to evaluate postoperative functional outcomes including voluntary bowel movements, soiling and constipation. Results: Twenty-seven patients were male and 12 were female. 12 patients underwent Boley and 27 patients Duhamel procedure. In the majority of patients, the pathology was in the rectosigmoid region (n:28, 71.79%). The rates of voluntary bowel movement were 83.33% in the Boley and 85.18% in the Duhamel group. There was no statistically significant difference between the two groups (p<0.05). No significant difference was found between the two groups in terms of the frequency and degree of soiling (Duhamel 22.21%, and Boley 16.66%, p>0.05). In the Duhamel group, constipation was more frequent than Boley group (p<0.05). Conclusion: Each technique has advantages and disadvantages compared to each other. In the majority of cases no serious complication is encountered, regardless of which technique is chosen for definitive surgery. It is recommended that the surgeon should continue to use the technique it is accustomed to and does well. © 2019 Turkey Association of Pediatric Surgery.Öğe Effects of olive oil applied to the nonfunctional distal colon on atrophic changes in patients undergoing ostomy(İnönü Üniversitesi, 2019) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; Gürsoy, DidarAim: Temporary colostomy is commonly performed for diseases requiring multi-stage surgery in pediatric surgical practice such as for anal atresia and Hirschsprung’s disease. Through this study, we aimed to decrease the diameter difference between the proximal and distal colon and subsequently provide surgical ease and to investigate the effect of 1-month application of pure olive oil, which is considered a trophic factor, to prevent distal colonic atrophy. Materials and Methods: In total, 24 pediatric patients who were treated at our clinic between June 2017 and November 2018 and who were scheduled to undergo colostomy closure were prospectively followed up. The patients were grouped into the following two groups: control group (n = 10), patients who were administered 5 cc 0.9% physiological saline solution twice a day for a month and olive oil group (n = 9), patients who were administered 5 cc pure olive oil as a trophic agent twice a day for a month. Results: There were significant differences in terms of mucosal thickness, muscular thickness, wall thickness, and colonic lumen diameter between the proximal and distal colon in the control group. On the other hand, in the olive oil group, there was no significant difference between the proximal and distal colon. However, there was a significant difference between the two groups in terms of first bowel movement and discharge times. Conclusion: Administration of olive oil from the distal colon opening prior to performing colostomy closure can decrease the diameter difference between the proximal and distal colons and provide easier surgical performance.Öğe Effects of probiotic use on bacterial translocation in created rat models with biliary obstructions(Atatürk Üniversitesi, 2019) Çelikkaya, Mehmet Emin; Akçora, Bülent; Hakverdi, Sibel; Özer, Burçin; Ulutaş, Kemal Türker; Duran, NizamiObjective: The aim of this study was to investigate the protective effects of the combined use of probiotic strains on the development of bacterial translocation in addition to liver and intestinal tissue damage due to biliary obstruction in rats. Materials and Methods: Here, 3 groups each consisting of 10 rats were created:group 1 (sham group), group 2 (obstructive jaundice), and group 3 (obstructive jaundice+probiotic). Groups 1 and 2 were given 1 cc physiological saline solution by oral gavage twice a day; group 3 was given a probiotic solution that included Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium bifidum, Enterococcus faecium, and Bifidobacterium longum microorganisms by oral gavage twice a day. Results: Markers for liver damage were also found to be significantly improved (p<0.05) in the treatment group (group 3). Whencompared with groups 2 and 3 in terms of liver histology, damage was found to be significantly more severe in group 2 (p<0.01). With regard to ileal villous depth and ileal inflammation, the pathology was found to be significantly more severe in group 2 than that in group 3 (p<0.05). In blood, spleen, and mesenteric lymph node cultures, group 2 showed a microbiological growth rate of 33.8–58.8%, whereas group 3 showed a microbiological growth rate of 14.3–28.6%. This reduction was evaluated to be statistically significant (p<0.05). Conclusion: Our study showed that the combined use of a probiotic in bile duct obstructions reduced bacterial translocation and alleviated pathological changes arising in the liver and terminal ileum histologyÖğe Effects of wrist fixation board in children on the complication rates of peripheral venous catheters(Ankara Eğitim ve Araştırma Hastanesi, 2019) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; El, Çiğdem; Akçora, BülentPURPOSE: Peripheral intravenous catheter (PIVC) insertion is the most frequently used invasive intervention that is performed in more than 80% of hospitalized children. It is a known that seemingly innocent PIVC may result in various morbidities such as phlebitis, infection, extravasations, and may even lead to mortality. In this study, we aimed to investigate the effect of a new fixation board (wrist-ankle fixation board) on PIVC lifespan and complications rates in pediatric patients undergoing PIVC insertion in the joint area. Material and methods: A total of 49 patients who were treated in the pediatric surgery ward between June and July 2018 and who underwent PIVC insertion were prospectively followed. The patients were divided into the following two groups: ‘Group 1’ in which a wrist-ankle fixation board was used and ‘Group 2’, which was allocated as the control group using Hypoallergenic Elastic Fixation Tape. PVC life and complications (infiltration, purification, displacement) were recorded. Results: Forty-nine patients were included in the present study and they were divided into the following two groups: 25 patients in Group 1 and 24 patients in Group 2. There were no statistically significant differences between the groups in terms of age and gender (p>0.05). There was no statistically significant difference in PIVC lifespan between Groups 1 (31.8 hours) and 2 (29.5 hours) (p = 0.151). The complication rate was noted to be 4% in Group 1 and 29% in Group 2. The difference in complication rates between the two groups was statistically significant (p = 0.02). Conclusions: The rate of complications was lower in pediatric patients with PIVC compared to the other method with the use of a new fixation board (ankle-ankle fixation fixation method). However, no significant results were obtained regarding PIVC life.Öğe EFFECTS OF WRIST FIXATION BOARD IN CHILDREN ON THE COMPLICATION RATES OF PERIPHERAL VENOUS CATHETERS(2019) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; El, Çigdem; Akçora, BülentPURPOSE: Peripheral intravenous catheter (PIVC) insertion isthe most frequently used invasive intervention that is performed inmore than 80% of hospitalized children. It is a known that seeminglyinnocent PIVC may result in various morbidities such as phlebitis,infection, extravasations, and may even lead to mortality. In this study,we aimed to investigate the effect of a new fixation board (wrist-anklefixation board) on PIVC lifespan and complications rates in pediatricpatients undergoing PIVC insertion in the joint area.Material and methods: A total of 49 patients who weretreated in the pediatric surgery ward between June and July 2018and who underwent PIVC insertion were prospectively followed.The patients were divided into the following two groups: ‘Group 1’in which a wrist-ankle fixation board was used and ‘Group 2’, whichwas allocated as the control group using Hypoallergenic ElasticFixation Tape. PVC life and complications (infiltration, purification,displacement) were recorded.Results: Forty-nine patients were included in the present studyand they were divided into the following two groups: 25 patientsin Group 1 and 24 patients in Group 2. There were no statisticallysignificant differences between the groups in terms of age and gender(p>0.05).There was no statistically significant difference in PIVC lifespanbetween Groups 1 (31.8 hours) and 2 (29.5 hours) (p = 0.151). Thecomplication rate was noted to be 4% in Group 1 and 29% in Group2. The difference in complication rates between the two groups wasstatistically significant (p = 0.02).Conclusions: The rate of complications was lower in pediatricpatients with PIVC compared to the other method with the use of anew fixation board (ankle-ankle fixation fixation method). However,no significant results were obtained regarding PIVC life.Öğe Evaluation of long-term lung capacity using spirometry in patients who underwent bronchoscopy due to foreign body aspiration(Çukurova Üniversitesi, 2019) Atıcı, Ahmet; Dikmen, Nursel; Çelikkaya, Mehmet Emin; El, Çiğdem; Akçora, BülentPurpose: The purpose of the present study was to evaluate the long-term lung status using spirometry in patients who underwent rigid bronchoscopy in acute period due to foreign body aspiration. Materials and Methods: Records of 142 children who underwent bronchoscopy due to foreign body aspiration between March 2013 and April 2018 were retrospectively reviewed. The data of 20 patients who cooperated with the spirometry process were included in this study (Group 1). Twenty patients who were admitted to the routine pediatric surgeon polyclinic without any lung problem and pain complaints were included in the study as a control group (Group 2). Forced expiratory flow rate (FEV1), forced vital capacity (FVC), FEV1/FVC, and forced expiratory flow at 25-75% of forced vital capacity (FEF 25–75) parameters were recorded in the first second. Results: Based on the statistical analysis results, there was no significant effect of age, sex, and BMI on FEV1, FVC, and FEF 25–75 values. The effect of bronchoscopy procedure on the same values, the difference between FEV1 and FVC values was statistically significant, whereas the difference between FEV1/FVC and FEF 25–75 values was not statistically significant for Groups 1 and 2. Conclusion: There was no long-term negative effect on lung capacities assessed using spirometry in our patients who received early-diagnosis and intervention within 24 h.Öğe Evaluation of the effects of zinc supplementation on the symptoms and duration of the disease in acute viral gastroenteritis(SERNEV, 2019) El, Çiğdem; Çelikkaya, Mehmet EminIntroduction: Acute viral gastroenteritis is the second most common cause of high morbidity and mortality in childhood. Viral gastroenteritis is the most common cause of severe diarrhea and associated hospitalizations especially in toddlers. It has been shown that the administration of 20 mg of zinc daily during acute diarrhea reduces the duration of watery diarrhea by 25% and it has been reported to have protective and therapeutic effects in the acute period. The aim of this study is to retrospectively determine the beneficial effects of oral zinc supplementation on the severity and duration of complaints of toddlers who were treated in our clinic with the diagnosis of acute viral gastroenteritis. Methods: Toddlers who were hospitalized in the Department of Pediatrics for acute viral gastroenteritis between October 2016 and March 2018 were included in the study. The study was retrospective and the data of the patients were obtained from the patient files. The diagnosis of acute viral gastroenteritis was made by detecting the adenovirus-rotavirus antigen in the fresh stool specimens. The patients were divided into two groups. Group 1: patients who received zinc supplementation in addition to support treatment. Group 2: patients who received only supportive therapy. Results: The mean number of vomiting was 3.60 / day and watery diarrhea was 5.20 / day in group-1 while number of vomiting was 6.1 / day and watery diarrhea was 8.9 / day in group-2 in the 36th hour during treatment. The tolerability of oral feeding at 36 th hour was 49.39% ( 41) in group-1 and 45.07% (32) in group-2. The mean number of vomiting and watery diarrhea in group-1 cases at 72th hours was 1.2 / day and 4.30 / day, while in group-2 cases, 3.90 / day and 7.20 / day. Conclusions: Although the physiopathology of the effects of zinc on gastroenteritis is not yet fully understood, diarrhea is seen both as a cause and as a result of zinc deficiency. The fact that patients with gastroenteritis benefit from zinc support suggests that zinc enhances this effect by increasing intestinal immunity.Öğe Hirschsprung hastalığında transabdominal Duhamel ve Boley prosedürlerinin karşılaştırmalı sonuçları(Türkiye Çocuk Cerrahisi Derneği ve Pediatrik Üroloji Derneği, 2019) Çelikkaya, Mehmet Emin; Atıcı, Ahmet; El, Çiğdem; Urfalı, Senem; Akçora, BülentAmaç: Hirschsprung Hastalığı (HD), intestinal gelişim sırasında nöral krest hücrelerinin göç başarısızlığından kaynaklanan bir nörokrestopatidir. Aganglionik kolon ile sonuçlanır ve çocuklarda fonksiyonel kabızlığa neden olur. Bu çalışmada, Boley ve Duhamel yöntemlerinin ardından HD’li hastalarda istemli barsak hareketleri, dışkı kaçırma ve kabızlık gibi fonksiyonel sonuçları karşılaştırmayı amaçladık. Yöntem: Boley veya Duhamel yöntemleri ile abdominal pull through yapılan hastalar çalışmaya dahil edildi. Tüm hastalara üç aşamalı operasyon uygulandı (ostomi açılması, definitif operasyon ve ostomi kapanması). İstemli bağırsak hareketi, dışkı kaçırma ve kabızlık dahil olmak üzere postoperatif fonksiyonel sonuçları değerlendirmek için Krickenbeck kriterleri kullanıldı. Bulgular: Hastaların 27’si erkek, 12’si kadındı. On iki hastaya Boley, 27 hastaya Duhamel yöntemi ile pull-through uygulandı. Hastaların çoğunda patoloji rektosigmoid bölgede idi (n: %28 71.79). Boley grubunda istemli bağırsak hareket oranı %83,33, Duhamel grubunda %85,18 idi. İki grup arasında istatistiksel olarak anlamlı fark yoktu (p>0,05). İki grup arasında dışkı kaçırma sıklığı ve derecesi açısından anlamlı fark bulunmadı (Duhamel %22,21, Boley %16,66, p>0,05). Duhamel grubunda kabızlık Boley grubundan daha fazlaydı (p<0,05). Tartışma: Her tekniğin birbirilerine göre avantaj ve dezavantajları vardır. Definitif cerrahide hangi tekniğin seçildiğinden bağımsız olarak vakaların çoğunda ciddi bir komplikasyona rastlanmaz. Cerrahın alıştığı ve iyi yaptığı tekniği kullanmaya devam etmesi önerilir.Öğe Infants with vitamin B12 deficiency-related neurological dysfunction and the effect of maternal nutrition(İnönü Üniversitesi, 2019) El, Çiğdem; Çelikkaya, Mehmet EminAim: Studies linked vitamin B12 deficiency in infancy are most commonly in patients with hematological and dermatological complaints rather than infant with neurodevelopmental retardation. In our study we aimed to evaluate the data of infants who presented with various neurological complaints and determined neurodevelopmental retardation due to vitamin B12 deficiency and also effects of maternal diet on the infants. Material and Methods: Infants who were admitted with various neurological complaints due to vitamin B12 deficiency between the dates of September 2016 and March 2018 were included in this study. Patients were retrospectively analyzed according to age, growth and development, clinical and laboratory findings (neurological, hematologic), continuation of breastfeeding, age at onset of complemantary food. During the pregnancy and lactation, the amount of feeding with animal foods, intake of vitamin supplements, duration of breastfeeding and vitamin B12 levels were examined. Results: The most common complaints were fatigue, pallor, no eye contact, apathy, vomiting, constipation, diarrhea, refusal to feed, retardation to growth and development, undeveloped or lost of ability (ability to tonic neck reflex, ability to sit supported and unsupported ability to sit). In the neurological examination of infants; iIn 13 infants, there was hypotonia, undeveloped ability to tonic neck reflex and ability to sit (supported and unsupported). Fifteen, in 15 infants just undeveloped ability to sit (supported and unsupported) and also in 6 infants had swallowing disorders. Conclusion: Vitamin B12 routinely to all pregnant women like folic acid and iron supplementation. In addition, developmental stages of infants should be evaluated and vitamin supplements should be given to infants when necessary.Öğe Is fixation suture necessary in undescended testicle surgery?(İnönü Üniversitesi, 2019) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; Akçora, BülentAim: It is still controversial whether or not testicular fixation is required for undescended testes surgery. In this study, we aimed to compare the results of the patients with undescended testis in a single center, who underwent orchiopexy with or without transfixation suture. Material and Methods: The medical records of the patients with undescended testes who were operated at our tertiary pediatric surgery department were retrospectively analyzed between July 2015 and November 2018. Patients were divided into two groups as fixation performed (Group 1) and not performed (Group 2). Group 1 included n=30 patients (40 testes) and Group 2 included n=41 patients (49 testes). The age of the patients, type of undescended testis, surgical technique and complication rates were determined Results: The mean age of the patients was 37.2 (12-104) months in Group 1 and 41.2 (12-110) months in Group 2. In both groups, complications such as recurrence, testicular atrophy, testis torsion, and hernia or hydrocele formation were not observed. One patient in Group 2 developed wound infection, which was recovered with antibiotic treatment. Conclusion: As a result of the short-term follow-up of our study, there was no clinically significant difference between the two groups. Therefore, we recommend the use of other techniques that do not include parenchymal suture fixation during orchiopexy, and avoiding the routine use of testicular parenchymal sutures if possible.Öğe Is there a predictive association between vitamin D concentrations and lower respiratory tract infections in infants?(İnönü Üniversitesi, 2019) El, Çiğdem; Çelikkaya, Mehmet EminAim: Vitamin D deficiency have been estimated to be endemic in the worldwide and in each age group and also it is reported that vitamin D has important effects on both natural and acquired immunity and there may be a relationship between deficiency and predisposition to infections The aim of this study is to investigate whether serum vitamin D level are effective in infant lower respiratory tract infection which is one of the most mortal infectious diseases in worldwide. Material and Methods: In our study, between October 2016 and January 2018 in Department of Pediatrics, the data of 418 infants with LRTI and their ages ranging from 5 to 24 months and were examined retrospectively. Vitamin D levels were studied in 106 of this patients. Results: In group-1, the mean duration of vitamin D supplementation was 4.9 months, while the mean in group-2 was 8.6 months. Breastfeeding time was 3.27 months in group 1 while it was 5.71 months in group 2. Both the duration of breastfeeding and the duration of vitamin D supplementation were shorter in group 1 than in group 2.Those difference between the groups was in terms of statistically significant (p< 0.05) Conclusion: Vitamin D deficiency in infants may be associated with LRTI, and even vitamin D deficiency may be a predisposing factor for severe LRTIs and also the frequency and severity of LRTIs can be reduced with optimal serum levels of vitamin D.Öğe Konjenital abdominal bantlara bağlı intestinal obstrüksiyon gelişen pediatrik olguların analizi: Tek merkez deneyimi(Türkiye Çocuk Cerrahisi Dergisi, 2019) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; Akçora, BülentAmaç: Daha önce batın operasyonu geçirmemiş hastalarda Ladd bantları ve omfalomezenterik kanal artığı (OMKA) gibi konjenital bantlara bağlı intestinal obstrüksiyonlar bilinmektedir. Atipik konjenital bantlar (AKB) ise, çocuklarda bağırsak tıkanıklığının son derece nadir nedenlerindendir. Bu çalışmada, nadir görülen pediatrik konjenital abdominal bant hastalarımızın geriye dönük olarak incelenmesi ve tek merkez sonuçlarının paylaşılması amaçlanmıştır. Yöntem: Temmuz 2004 - Kasım 2018 yılları arasında ileus nedeniyle ameliyat edilen 204 hastanın dosyaları geriye dönük olarak incelendi. Çalışmaya daha önceden operasyon öyküsü olmayan ve konjenital abdominal bant nedeniyle ameliyat edilen 17 hasta dahil edildi. Bulgular: Hastaların 10’u erkek, 7’si kız idi. Yaş ortalaması 3,2 yıl (0,1-15) olarak bulundu. Hastaların %53’ünde (n=9) malrotasyona bağlı ladd bantları, %29’ında (n=5) OMKA bağlı bantlar ve %18’inde (n=3) AKB vardı. Tedavide OMKA bağlı hastaların %60’ına (n=3) bağırsak rezeksyonu gerekirken (30-40-65 cm), ladd bantlarına ve AKB bağlı hastaların hepsinde bant eksizyonu yeterli oldu, hiçbir hastaya bağırsak rezeksyonu gerekmedi. Hastaların tamamı şifa ile taburcu edildi. Sonuç: Pediatrik konjenital bantlar farklı etiyolojilere sahip hastalıkları içerir. Daha önceden batın ameliyatı olmamış ve ileus tablosuyla gelen bir hastada ayırıcı tanıda malrotasyona bağlı ladd bantları ve OMKA ile birlikte AKB’ninde akılda bulundurulması gerekmektedir.Öğe Koroziv madde alımı olan çocukların uzun dönem akciğer kapasitelerinin spirometri ile değerlendirilmesi(2022) Atıcı, Ahmet; Dikmen, Nursel; Çelikkaya, Mehmet EminAmaç: Bu çalışmada korozif madde alımı sonucu özofagus striktürü gelişen ve mükerrer defa özofagus dilatasyonu işlemi yapılan hastaların uzun dönem akciğer durumlarının spirometri ile değerlendirilmesi amaçlanmıştır. Yöntem: Ocak 2014 – Mayıs 2021 tarihleri arasında merkezimize KMA nedeniyle başvuran hastalar retrospektif olarak incelendi. Hastalar; Grup 1: Kontrol grubu (n=23) Grup 2: Korozif madde alımı sonrası dilatasyon işlemine ihtiyacı olmayan ve kür sağlanmış hastalar (n=9) Grup 3: Korozif madde alımına bağlı özofagus striktürü gelişen ve genel anestezi altında dilatsyon işlemi uygulanan hastalar (n=9) olarak üç gruba ayrıldı. Değerlendirme için; 1. Saniyedeki zorlu ekspiratuar akım hızı (FEV1), zorlu vital kapasite (FVC), FEV1/FVC ve zorlu ekspirasyon ortası akım hızı (FEF 25-75) parametreleri kaydedildi. Bulgular: Yapılan istatistik analizi sonuçlarına göre FEV1, FVC ve FEF 25-75 gibi değerlerin üzerinde dilatasyon işleminin etkisi incelendiğinde Grup 1-2 için FEV1 (p=0.02) ve FVC (p =0,01) değerleri arasındaki fark istatistiksel olarak anlamı, grup1-3 ve grup 2-3 arasında anlamsız (p>0,05) saptandı. FEV1/FVC (p>0.05) ve FEF 25-75 (p>0.05) arasında hiçbir grupta anlamlı fark saptanmadı. Sonuç: Hastalarımızın spirometre ile değerlendirilen akciğer kapasitelerinde uzun dönem olumsuz bir etkilenme tespit edilememiştir.Öğe Nadir bir vestibüler kitle nedeni: Dokuz yaşındaki kız çocukta üretra prolapsusu(2020) Atıcı, Ahmet; Ekinci, Halime; Çelikkaya, Mehmet Emin; Akçora, BülentÜretra prolapsusu distal üretral mukozanın eksternal meatal açıklık boyunca sirküler şekilde protrüzyonuile karakterize çok nadir bir hastalıktır. Dokuz yaşında kız hasta ağrısız lekelenme tarzıvajinal kanama yakınması ile çocuk cerrahisi polikliniğine başvurdu. Hastanın yapılan fizik muayenesindevestibulumda yaklaşık 2x2 cm eksternal meadan prolabe olan yuvarlak, kırmızımsırenkte ödemli, frajil kitle izlendi. Hasta elektif şartlarda ameliyat edildi ve ameliyat sonrası birincigünde sorunsuz taburcu edildi. Bu yazıda dokuz yaşında üretra prolapsusu nedeniyle başvuranve cerrahi olarak tedavi edilen bir kız hastanın sunulması amaçlanmıştır.Öğe Outcomes in Paediatric Patients Presenting with a Complaint of Breast Swelling: A Retrospective Single-centre Study(2022) Atıcı, Ahmet; Çelikkaya, Mehmet Emin; Korkmaz, İnan; Akçora, BülentObjective: Although malignancy is very rare in paediatric breast lesions, the presence of breast swelling is generally worrying for patients and their families. Breast masses affect approximately 2% to 3% of females in childhood . However, the rate of breast swelling associated with normal pubertal development in children admitted to hospital with a complaint of breast swelling is unknown. This study aimed to retrospectively examine the diagnoses of children presenting with a complaint of breast swelling. Methods: A retrospective sample comprising the medical case records of paediatric patients (N=50; male:13; female: 37; mean age: 13.2 years old) admitted to the Mustafa Kemal University hospital with a complaint of breast swelling between April 2017 and December 2021 was included in the study Results: For males, the most common cause of breast swelling was normal pubertal development (53.8 %; n=7), followed by gynecomastia (30.7%; n=4), and neonatal breast hypertrophy (15.3%; n=2). For females, the most common cause of breast swelling was a mass in the breast (35.1%; n=13), followed by a breast cyst (16.2%; n= 6), normal pubertal development (29.8%; n=11), and finally asymmetric breast development (18.9%; n=7). The majority of cases (86%; n=43) were treated conservatively; the remainder (14%; n=7) underwent surgical treatment. Conclusion: There is a wide spectrum of diagnoses in children presenting with a complaint of breast swelling, most of them are benign. It should be kept in mind that anxious patients who present with a complaint of breast swelling may only be experiencing normal pubertal development. Although all the patient cases examined in the present study involved benign masses, it is important to plan diagnosis and treatment without delay to ensure the early diagnosis of malignant diseases.