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Öğe Blood-pool SPECT in addition to bone SPECT in the viability assessment in mandibular reconstruction(Verduci Publisher, 2014) Aydogan, F.; Akbay, E.; Cevik, C.; Kalender, E.INTRODUCTION: The assessment of the postoperative viability of vascularized and non-vascularized grafts used in the reconstruction of mandibular defects due to trauma and surgical reasons is a major problem in maxillofacial surgery. AIM: In the present study, we evaluated the feasibility and image quality of blood-pool SPECT, which is used for the first time in the literature here in the assessment of mandibular reconstruction, in addition to non-invasive bone scintigraphy and bone SPECT. We also evaluated whether it would be useful in clinical prediction. PATIENTS AND METHODS: Micro-vascularized and non-vascularized bone grafts were used in 12 Syrian men with maxillofacial trauma. Between days 5-7 after surgery, three-phase bone scintigraphy, blood-pool SPECT and delayed bone SPECT scans were performed. After month 6, the patients were assessed by control CT scans. RESULTS: Of the non-vascularized grafts, one graft was reported as non-viable at week one. At month 6, graft resorption was demonstrated on the CT images. The remaining non-vascularized grafts and all of the micro-vascularized grafts were considered to be viable according to delayed bone SPECT and blood-pool SPECT images. However, only the anterior and posterior ends could be clearly assessed on delayed SPECT images, while blood-pool SPECT images allowed the clear assessment of the entire graft. CONCLUSIONS: The combined use of blood-pool and delayed SPECT scans could allow for better assessment of graft viability in the early period, and can provide more detailed information to clinicians about prognosis in the follow-up of patients undergoing mandibular graft reconstruction.Öğe Correlation of carboxyhemoglobin levels and secondhand smoking related complications in pediatric tonsillectomy patients(Lippincott Williams & Wilkins, 2014) Koyuncu, O.; Turhanoglu, S.; Davarci, I; Cevik, C.; Sessler, D., I; Turan, A.[Abstract Not Available]Öğe Dermoid cyst: A rare entity of the parotid gland(Springer, 2013) Toprak, S.; Ozgur, T.; Gokce, H.; Cevik, C.; Akbay, E.; Atik, E.[Abstract Not Available]Öğe Electron microscopic examination of effects of bogma raki and walnut on cochlea: An experimental study(Sage Publications Ltd, 2015) Cevik, C.; Ozler, G. S.; Arli, C.; Tatar, I.; Sargon, M. F.; Zeren, C.; Yonden, Z.Illegal alcohol beverages known as bognna raki in our country are consumed widely in our region. The studies investigating the relationship between alcohol consumption and hearing ability report different results. In this study, we aimed to investigate the toxic effects of bogma raki that contains neurotoxic substances on cochlea by electron microscopy. To the best of our knowledge, this study is the first in the literature. A total of 48 Wistar male albino rats (aged 12-16 weeks and weighing 200-240 g) were used in the study. The rats were divided into 4 groups with 12 animals in each group. The groups include control, bogma raki, walnut, and walnut + bogma raki groups. Bogma raki (30% v/v, 9.2 ml kg(-1) day(-1)) is added to drinking water of rats in bogma raki group (n = 12) for 4 weeks. Walnut group rats (n = 12) are fed with standard rat food and walnut without limitation (10 g kg(-1) day(-1)). Bogma raki + walnut group rats (n = 12) are fed with standard rat food and walnut and bogma raki is added to drinking water. The cochleas were dissected and removed en bloc and examined by electron microscopy. Perineuronal oedema around neurons of spiral ganglion and hairy cells of organ of Corti were present in the bogma raki group, walnut group and bogma raki + walnut group under electron microscopic examination. Comparing these three groups, there were no differences in the ultrastructural pathological changes. In the ultrastructural examination of the myelinated axons forming cochlear nerve, no ultrastructural pathology was detected in all the groups.Öğe The endothelial nitric oxide synthase (eNOS) polymorphism in otitis media with effusion (OME)(Elsevier Masson, Corporation Office, 2017) Ates, M.; Cevik, C.; Dokuyucu, Recep; Berber, O.; Colak, S.; Izmirli, M.Objectives: Otitis media with effusion (OME) is the most common disease after viral infections of upper respiratory tract (URTI) in children. Studies indicate the important role of nitric oxide (NO) in the etiology of hearing loss. However, there is no study that focuses on the role of nitric oxide synthase (eNOS) polymorphisms in the cases with OME. The aim of the present study is to evaluate the eNOS polymorphisms in the pediatric patients with OME. Materials and methods: Eighty-nine patients who are diagnosed with otitis media with effusion and 85 healthy subjects who are compatible in terms of age and gender were included in the study. All patients in the study were subjected to complete ear, nose, throat (ENT) and audiological examinations. DNA analysis was performed with polymerase chain reaction (PCR) technique from the blood samples. The PCR product was cut by restriction fragment length polymorphism (RFLP) with BanII enzyme and checked by agarose gel electrophoresis. Results: As a result of genetic analysis, there is no significant difference between patients and the controls in terms of eNOS Glu298Asp polymorphism (G/G, G/T, T/T). When these groups were compared in terms of allele distributions, a significant relationship was found between the patients and the controls (P = 0.037). Conclusion: To the best of our knowledge, G allele was identified as predisposing to the development of OME and this is the first report indicates the correlation between the eNOS G894T polymorphism and OME in Turkey. (C) 2016 Elsevier Masson SAS. All rights reserved.Öğe Investigation of demodex species frequency in patients with a persistent itchy ear canal treated with a local steroid(Cambridge Univ Press, 2014) Cevik, C.; Kaya, O. Aycan; Akbay, E.; Yula, E.; Yengil, Erhan; Gulmez, M. I.; Akoglu, E.Objective: To investigate the frequency of demodex species in the external acoustic meatus in patients with an itchy ear canal. Methods: Patients were assigned to one of three groups. Group one consisted of 54 patients with an itchy ear canal who were using a local agent, while group two was composed of 51 patients with an itchy ear canal who were not using a local agent. Group three consisted of 50 healthy individuals without an itchy ear canal. Results: Demodex species test results were positive in nine (5.8 per cent) of the cases. Six of these positive cases were in group one, two in group two and one in group three. The frequency of demodex species in the external acoustic meatus was similar between those patients with an itchy ear canal who did not use a local agent and the healthy individuals (p = 0.571), but it was significantly higher in those using a local steroid compared with those not using a local agent (p = 0.046). Conclusion: Although demodex species was not significantly higher in patients with an itchy ear canal compared with the control group, use of a local steroid increased the parasite frequency in the external ear canal of affected patients.Öğe Myiasis based on squamous cell carcinoma of the external auditory canal(Galenos Yayincilik, 2011) Cevik, C.; Akbay, E.; Arli, C.; Gulmez, M. I.Myiasis is an infestation that occurs by flies larvae. Usually it appears in the dead animals residues and garbage but rarely seen at intact skin or necrotic areas. myiasis cases appears uncommon in our country. In this study we aimed to Show patient with myiasis based on squamous cell carcinoma of the auricula who did not considered surgery interference and any therapy.Öğe New Mediterranean Biodiversity Records (December 2011)(Natl Centre Marine Research, 2011) Eleftheriou, A.; Anagnostopoulou-Visilia, E.; Anastasopoulou, E.; Ates, S. A.; Bachari, N. El I.; Cavas, L.; Cevik, C.The present work reports on recent biodiversity records of Mediterranean native species such as Olindias phosphorica in the Turkish Aegean Sea and extended distribution of eleven alien species in the Mediterranean. These are: Bursatella leachi (Mollusca, Gastropoda: Algeria); Callinectes sapidus (Crustacea, Decapoda: Greek Ionian Sea); Caprella scaura (Crustacea, Amphipoda: Mar Piccolo of Taranto); Fistularia commersonii (Fish: Saronikos Gulf, Aegean Sea); Sphoeroides pachygaster (Fish: South Turkey); Musculista perfragilis (Mollusca, Bivalvia: South Turkey); Sepioteuthis lessoniana (Mollusca, Cephalopoda: central eastern coast of Tunisia); Flabellina rubrolineata (Mollusca, opisthobranchia: central Aegean, Greece); Hesionura serrata (Polychaeta: Apulian coast); Stephanolepis diaspros (Fish: Saronikos Gulf, Aegean Sea); and Parvocalanus crassirostris (Crustacea, Copepoda: Lesvos Island, Greek Aegean Sea).Öğe Topical steroid induced chronic eczematous external otitis with consisting of external ear cavity: A case report(Galenos Yayincilik, 2012) Arli, C.; Cevik, C.; Akbay, E.; Acikalin, A.Chronic eczematous external otitis is often seen in older women, and constant itching outer ear. The inlet part of the external auditory canal red, scaly, dry, and often there is no serumen the remaining parts of the canal. Eighty-year-old male patient with chronic eczematous external otitis due to topical clobetasol propionate were using for nearly 20 years. In the patient's examination, the left auricle is slightly faded and from the external ear canal cartilage instead of bone union was observed ranging from a cavity. Tympanic membrane was normal but pointed out that a slight atrophy of the bone parts of the external ear canal. In this article we will discuss with patients the side effects of long term use of topical steroids.