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Öğe Audiological and transient evoked otoacoustic emission findings in patients with vitiligo(Sage Publications Ltd, 2010) Aslan, Sundus; Serarslan, Gamze; Teksoz, Emel; Dagli, SafakOBJECTIVE: To investigate hearing loss in patients with vitiligo. STUDY DESIGN: Case-control study. SETTING: University hospital. SUBJECTS AND METHODS: Conventional pure-tone and high-frequency audiometric tests were obtained, and pure-tone average hearing thresholds were calculated for 22 consecutive cases with vitiligo and 22 sex- and age-matched controls. Transient evoked otoacoustic emission testing was also performed. RESULTS: There was sensorineural hearing loss on pure-tone audiogram in 16 (36.4%) ears in patients with vitiligo. The hearing thresholds (in dB) were 16.02 +/- 6.61 versus 12.39 +/- 6.05, 15.68 +/- 6.34 versus 13.18 +/- 3.75, 15.80 +/- 13.93 versus 7.39 +/- 6.95, 25.11 +/- 17.40 versus 15.91 +/- 12.91, 29.89 +/- 18.57 versus 17.84 +/- 12.36, and 45.91 +/- 23.31 versus 33.86 +/- 15.99 in the patient and control groups at 0.25, 1, 4, 8, 10, and 12.5 kHz, respectively, and were statistically significantly different. Reduction of transient evoked otoacoustic emission amplitude was statistically significant at 4 kHz in patients with vitiligo (6.34 +/- 3.98 dB vs 8.63 +/- 5.15 dB, P = 0.023). There was no significant difference in reproducibility, stimulus intensity, stability, and average transient evoked otoacoustic emission amplitudes in patients with vitiligo. CONCLUSION: Hearing thresholds at pure-tone and high-frequency audiometry were higher in patients with vitiligo. Also, significantly lower high-frequency amplitudes were recorded during transient evoked otoacoustic emission testing in the disease group. (c) 2010 American Academy of Otolaryngology Head and Neck Surgery Foundation. All rights reserved.Öğe The effect of anesthetic agents on perioperative bleeding during tonsillectomy: Propofol-based versus desflurane-based anesthesia(Mosby-Elsevier, 2008) Okuyucu, Semsettin; Inanoglu, Kerem; Akkurt, Cagla Ozbakis; Akoglu, Ertap; Dagli, SafakOBJECTIVE: Hemorrhage during tonsillectomy is related to the surgical technique, management of bleeding, and choice of anesthetic agent. This study evaluated the effects of anesthetic agents on hemorrhage during tonsillectomy with standardized surgical techniques and management of bleeding. STUDY DESIGN: Double-blind, randomized controlled trial. SUBJECTS AND METHODS: Sixty patients, aged 3 to 12 years, who were scheduled for elective tonsillectomy were enrolled in the study. Propofol-based anesthesia was administered to the first group; desflurane-based anesthesia, to the second. The amount of blood loss due to hemorrhage was measured. RESULTS: Propofol-based anesthesia significantly decreased bleeding during tonsillectomy. CONCLUSION: Propofol-based anesthesia is a reliable method for use in children who undergo tonsillectomy. (C) 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.Öğe The effect of dacryocystorhinostomy on mucociliary function(Mosby-Elsevier, 2009) Okuyucu, Semsettin; Akoglu, Ertap; Oksuz, Huseyin; Gorur, Hatice; Dagli, SafakOBJECTIVE: External dacryocystorhinostomy is suspected to cause mucociliary dysfunction by affecting ciliary activity and quality of the mucus. We hypothesized that patients who undergo endoscopic dacryocystorhinostomy may also experience mucociliary dysfunction. We evaluated the effects of surgery on mucociliary clearance time in patients who underwent endoscopic dacryocstorhinostomy and external dacryocstorhinostomy. STUDY DESIGN: A prospective controlled study. SUBJECTS AND METHODS: Forty-four patients were studied: 22 had undergone one-sided endoscopic Surgery and 22 had undergone one-sided external surgery for nasolacrimal duct obstruction. Nonoperated sides of the both groups were remained as controls. The saccharin test was used to evaluate the mucociliary clearance time of the both sides. RESULTS: Dacryocystorhinostomy, results in prolonged mucociliary clearance times either endoscopic or external approach is performed (P < 0.001, paired t test). There was no significant difference between the mucociliary clearance times after endoscopic and external dacryocystorhinostomy), (P = 0.22, Student's t test). CONCLUSION: Dacryocystorhinostomy impairs mucociliary function independent of the type of surgery.Öğe Ex Vivo Tracheal Mucociliary Clearance in Rats: Comparisons of Nebulization versus Irrigation with Lactated Ringer and Saline Solutions(Bmc, 2009) Okuyucu, Semsettin; Akoglu, Ertap; Babayigit, Cenk; Akoglu, Sebahat; Dagli, SafakObjective: This study was performed to compare the effects of isotonic saline, hypertonic saline (buffered/nonbuffered), and lactated Ringer irrigation and distilled water nebulization on mucociliary clearance in ex vivo rats. Design: Experimental study. Setting: Tertiary otolaryngology care centre. Methods: Thirty rat tracheas were achieved from 15 rats by dividing the trachea longitudinally into two equal parts. Main Outcome Measures: Mucociliary transport velocity was measured by direct observation of particle placed on the lower end of the trachea after irrigation or nebulization. Results: Significant improvement in mucociliary clearance was found with isotonic saline (p = .002), buffered hypertonic saline (p = .018), lactated Ringer (p = .000), and nebulized distilled water (p = .000) when compared with nonbuffered hypertonic saline. Conclusion: Lactated Ringer solution is better than saline solution at enhancing mucociliary clearance, but nebulized distilled water is superior to the tested irrigation solutions in rat tracheal epithelium.Öğe Formaldehyde technique in dimensional stability of free fascia: An animal study(Taylor & Francis As, 2010) Aslan, Sundus; Savas, Nazan; Ozsoy, Sule Yurdagul; Dagli, SafakConclusion. Despite the fact that this was a study done with fascia other than the temporalis, we found that non-formaldehyde-formed and formaldehyde-formed fascia graft shrunk by a mean value of 26.5%, and 16.7%, respectively, which was statistically significant. This finding might be the explanation for the consistently reported successful outcomes in tympanoplasty carried out with formaldehyde-formed temporalis fascia. However, this study should be validated with autologous human temporalis fascia graft. Objectives. To determine whether there is any difference in the dimensional stability of free fascia grafts when formed with formaldehyde or not. Materials and methods. In a total of 22 rats, free fascias were prepared with 4% buffered formaldehyde solution in 11 and without formaldehyde in the other 11 rats. All fascia grafts of 1 x 1 cm were implanted under the insicion site of the same rat (autograft). All rats were re-operated after 5 days to measure the dimensions of the grafts. The postoperative changes in the dimensions were calculated. Results. By the 5th day, the mean non-formaldehyde-formed graft surface area was 73.51 +/- 13.43 mm(2) and the mean formaldehyde-formed graft surface area was 83.28 +/- 10.50 mm(2) respectively. After 5 days there was a mean decrease in surface area of the non- formaldehyde-formed and formaldehyde-formed grafts of 26.49 +/- 13.43 mm and 16.72 +/- 10.50 mm(2), respectively. It was found that formaldehyde-formed fascia exhibited significantly superior dimensional stability when compared with non-fixed fascia during the 5 days of the early healing phase (p=0.031).Öğe Giant retropharyngeal abscess in an adult as a complication of acute tonsillitis: Case report(Medquest Communications LLC, 2009) Ozbek, Cem; Dagli, Safak; Tuna, E. Evrim Unsal; Ciftci, Onur; Ozdem, CaferRetropharyngeal abscess is an uncommon entity that can have severe and even fatal complications if it is not identified and treated early. Clinical and radiologic findings must be considered together prior to surgical drainage of a suspected retropharyngeal abscess. Airway obstruction may require emergent surgical management with tracheotomy. We describe the case of a 22-year-old man with a massive retropharyngeal abscess that was caused by inadequate treatment of acute tonsillitis. He responded well to surgical drainage and empiric antibiotic therapy.Öğe ISOLATED CYST HYDATID: AN UNUSUAL CAUSE OF A MASS IN THE NAPE OF THE NECK(Nobel Ilac, 2009) Okuyucu, Semsettin; Balcı, Ali; Karazincir, Sinem; Akoglu, Ertap; Gozel, Serhat; Dagli, SafakBecause of the rarity of hydatid cyst in the head and neck area, it may be overlooked by the clinicians. We report a case of primary hydatid cyst in the posterior cervical region without another organ involvement. A 54-year-old woman presented with a large, painless lump in the nape of the neck. A computed tomography scan demonstrated a 5x5x4 cm hypodense mass which is located in the left scalen muscles. An axial magnetic resonance image revealed well-defined high signal intensity mass with low signal intensity rim, which is considered as a characteristic feature for hydatid cyst. She underwent surgery to excise the cyst. Histopathological examination confirmed the diagnosis as a hydatid cyst. If a cystic mass in head and neck area exists, hydatid disease must be kept in mind, especially in endemic areas, to avoid the complications such as acute anaphylaxis or recurrences due to inappropriate management.Öğe Prolene®: a novel, cheap, and effective material in dacryocystorhinostomy(Taylor & Francis As, 2009) Aslan, Sundus; Oksuz, Huseyin; Okuyucu, Semsettin; Akoglu, Ertap; Dagli, SafakConclusion. Prolene (R) is cheap, effective, and readily available in almost all operating theaters. It might be used successfully in endoscopic dacryocystorhinostomy and is promising as an alternative to silicone stent intubations, especially in settings with limited resources. Objective. To evaluate the clinical efficacy and results of stenting with polypropylene (Prolene (R),Ethicon, Inc.) suture material instead of silicone tube in endoscopic dacryocystorhinostomy. Patients and methods. Forty-two endoscopic dacryocystorhinostomy operations were performed in 36 patients (I I men and 25 women; mean age 34.7 +/- 9.5 years, range 16-60 years) between 2007 and 2008. After creating an aperture in the medial wall of the lacrimal sac, 2/0 Prolene was inserted through the canaliculi into the sac. The Prolene was left in the lacrimal sac for 3 months. The patients were followed up for between 6 and 18 months (mean 8.1 +/- 3.6 months). The improvement in the complaint of epiphora was grouped as very good, good, or no change. Results. The improvement in 34 eyes (81%) was reported as very good, whereas improvement was noted as good in 5 eyes (11.9%), and there was no change in 3 eyes (7.1%). We observed granulation tissue formation around the Prolene in two patients.Öğe Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: A randomized controlled study(Elsevier Ireland Ltd, 2006) Akoglu, Ertap; Akkurt, B. Cagla Ozbakis; Inanoglu, Kerem; Okuyucu, Semsettin; Dagli, SafakObjective: To compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children. Methods: Forty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n = 16) received bupivacaine, group 2 (n = 15) received ropivacaine, and a group 3 (control) (n = 15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24 h postoperatively. Results: No difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p > 0.05). The pain scores in both analgesia groups were significantly (p < 0.05) lower 1, 4, 12, 16, and 24 h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p < 0.05) different between the analgesia and control groups. Conclusion: Local ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain. (C) 2005 Elsevier Ireland Ltd. All rights reserved.
