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Öğe Electrolyte Abnormalities in Patients with Type 2 Diabetes Mellitus(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2017) Ozsan, Muge; Yaprak, Mustafa; Ozcan, Oguzhan; Kiriktir, Esra; Turgut, FarukOBJECTIVE: The aim of the was is to evaluate electrolyte changes and the relationship between electrolytes and glucose regulation in type 2 diabetic patients. MATERIAL and METHODS: Data of diabetic patients aged 30-90 years who came to the Endocrinology and Metabolism and the Nephrology outpatient clinics between 01.02.2015 and 30.12.2015 for any reason were reviewed. Patients with type 1 diabetes mellitus, using diuretics, renin-angiotensin-aldosterone system blockers or combination of these drugs, or calcium, magnesium, vitamin D supplementation, patients with vomiting and diarrhea, serious heart failure, cirrhosis, active malignancy, estimated glomerular filtration rate <= 60 mL/min 1.73 m(2), and those diagnosed with diabetic ketoacidosis are excluded from the study. RESULTS: According to the inclusion and exclusion criteria, 323 type 2 diabetic patients consisting of 161 women and 162 men were evaluated. Hypomagnesemia was the major electrolyte problem in our study group with a prevalence of 20.2%. A negative correlation was observed between serum glucose and sodium (p<0.05; r=-0.28). There was no correlation between glucose and other electrolytes (potassium, calcium, phosphorus and magnesium). CONCLUSION: Electrolyte imbalances are frequently seen in diabetic patients because of physiopathologic changes and therapeutic drugs as well as comorbidities. Evaluation of electrolytes during the follow up period of these patients, and in the case of any electrolyte abnormalities their appropriate management is important for decreasing both mortality and morbidity.Öğe The High Number of Hemodialysis Patients in Hatay Province and Possible Causes(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2016) Turgut, Faruk; Yaprak, Mustafa; Ozsan, Muge; Guler, Gokhan; Bardakci, MehmetOBJECTIVE: We aimed to compare the number of the patients receiving hemodialysis therapy and the causes of underlying renal disease in Hatay and Turkey, and to discuss the possible causes. MATERIAL and METHODS: The number of the patients on chronic hemodialysis, and the causes of underlying renal disease were recorded from hemodialysis centers in Hatay. The Ministry of Health of Turkey Dialysis Information Management System data and Turkish Society of Nephrology Registry data were used to obtain data of the patients on chronic hemodialysis in Turkey in general and in the neighboring provinces. RESULTS: It was observed that the number of hemodialysis patients per million population was quite high compared to the neighboring provinces. By the year 2014, the number of patients receiving hemodialysis was 1.487 with a prevalence of 978 and an incidence of 156 per million population. Both the prevalence and incidence were quite high in our region compared with the general numbers for Turkey. When we looked at the causes of underlying renal disease in hemodialysis patients in Hatay province, the most common cause was diabetes at 46.2% and hypertension was the second most common cause at 27.1%. CONCLUSION: The prevalence of end-stage renal disease and diabetic kidney disease was found to be quite high compared to the general numbers for Turkey and the results showed that diabetes is an important health problem for the region.Öğe Higher Serum Bisphenol A Levels in Diabetic Hemodialysis Patients(Karger, 2016) Turgut, Faruk; Sungur, Sana; Okur, Ramazan; Yaprak, Mustafa; Ozsan, Muge; Ustun, Ihsan; Gokce, CumaliBackground: Bisphenol A (BPA) has been implicated as an 'endocrine disruptor'. We aimed at exploring the association between serum BPA levels and patient characteristics, particularly the presence of diabetes mellitus, and laboratory parameters in hemodialysis patients. Methods: This study included 47 chronic hemodialysis patients. Patient characteristics were recorded. Blood was drawn before and after hemodialysis session. Serum BPA levels were measured by the high-performance-liquid-chromatography and laboratory parameters were measured by using standard methods. Results: In hemodialysis patients, postdialysis serum BPA levels were significantly higher than predialysis after a single hemodialysis session (5.57 +/- 1.2 vs. 4.06 +/- 0.73, p < 0.0001). Predialysis serum BPA levels were significantly higher in patients with diabetes than non-diabetics (4.4 +/- 0.6 vs. 3.9 +/- 0.7, p = 0.025). No association was found between serum BPA levels and patient characteristics, and particularly laboratory parameters. Conclusion: Serum BPA levels were rising significantly after a single dialysis session. Diabetic hemodialysis patients had higher predialysis serum BPA levels. (C) 2016 S. Karger AG, BaselÖğe The Incidence of Demodex folliculorum in the Combination of Allergic Rhinitis and Diabetes Mellitus(Iranian Scientific Society Medical Entomology, 2019) Arli, Cengiz; Ozsan, Muge; Gurkan, Eren; Kaya, Ozlem Aycan; Kokacya, SumeyyaBackground: Demodex mites are permanent ectoparasites of human pilosebaceous unit. They mainly infect skin of the face and scalp. Many studies have shown hi er density of the ectoparasites in diseased inflammatory skin than in normal skin. The aim of this study was to determine the frequency of Demodexfolliculorum (DE) in treatment-resistant patients with the combination of allergic rhinitis (AR) and diabetes mellitus (DM). Method: This study was conducted in 2014-2017. It included 92 patients aged 18-70 years who presented at the Ear, Nose and Throat (ENT) and Endocrinology Polyclinics of Mustafa Kemal University Medical Faculty Hospital, Turkey. An age and gender matched control group was formed of 30 healthy individuals. To determine the presence of DF, a few eyelashes were taken from eyelids in both groups. Then samples were examined under a light microscope. Results: DF positivity was determined in 44 (47.8%) of the 92 patients and in 1 (3.3%) of the 30 control group subjects. In the patient group, DF positivity was evaluated as present in 14 (43.7%) of the DM patients, in 12 (40%) of the AR patients and in 18 (60%) of the AR+DM patients. Statistically significant DF incidence was found in all three patient groups compared to the control group (P=0.001). The incidence in AR + DM group was not different from other patient groups. Conclusion: DM, AR, advanced age and obesity had prepared the environment for Demodex infestations. This issue should be considered especially in treatment of patients with AR+DM.Öğe The incidence of Demodex folliculorum in the combination of allergic rhinitis and diabetes mellitus(Tehran University of Medical Sciences (TUMS), 2019) Arlı, Cengiz; Ozsan, Muge; Gurkan, Eren; Aycan Kaya, Ozlem; Ko-Kacya, SumeyyaBackground: Demodex mites are permanent ectoparasites of human pilosebaceous unit. They mainly infect skin of the face and scalp. Many studies have shown higher density of the ectoparasites in diseased inflammatory skin than in normal skin. The aim of this study was to determine the frequency of Demodex folliculorum (DF) in treatment-resistant patients with the combination of allergic rhinitis (AR) and diabetes mellitus (DM). Method: This study was conducted in 2014-2017. It included 92 patients aged 18-70 years who presented at the Ear, Nose and Throat (ENT) and Endocrinology Polyclinics of Mustafa Kemal University Medical Faculty Hospital, Turkey. An age and gender matched control group was formed of 30 healthy individuals. To determine the presence of DF, a few eyelashes were taken from eyelids in both groups. Then samples were examined under a light microscope. Results: DF positivity was determined in 44 (47.8%) of the 92 patients and in 1 (3.3%) of the 30 control group subjects. In the patient group, DF positivity was evaluated as present in 14 (43.7%) of the DM patients, in 12 (40%) of the AR patients and in 18 (60%) of the AR+DM patients. Statistically significant DF incidence was found in all three patient groups compared to the control group (P=0.001). The incidence in AR + DM group was not different from other patient groups. Conclusion: DM, AR, advanced age and obesity had prepared the environment for Demodex infestations. This issue should be considered especially in treatment of patients with AR+DM. © 2019, Tehran University of Medical Sciences (TUMS). All rights reserved.Öğe The Use of Herbal Supplements of Diyabetic Patients Attending the University Hospital in Hatay, Endocrine Polyclinic(Duzce Univ, 2017) Pinar, Neslihan; Topaloglu, Meyli; Ozsan, Muge; Ozer, Cahit; Alp, HarunObjective:Today, people are increasingly interested in complementary and alternative medicine (TAT) practices. These are the most preferred herbal products by patients. Herbal products are also widely used in diyabetes patients. The use of herbal products in diyabetic patients can lead to morbidity and mortality. The present study aimed to investigate the use of herbal supplements in diyabetic patients as well as the methods of administration and the side effects of the products. Methods:The cross-descriptive study was carried out from May to June 2016 and enrolled 150 patients aged over 18 years who applied to Mustafa Kemal University Medical Hospital Endocrinology Outpatients. Results:Of the 150 participants, 60.7% (n:91) were male while 39.3% (n:59) were female and 22% (n:33) of them reported herbal supplement use. The most preferred supplements were, cinnamon 5.3% (n:8), lemon 4.7% (n:7), pomegranate syrup 3.3% (n:5), green tea 2.7% (n:4), 2.0% almond (n:3), 1.3% (n:2) yarrow, sage and olive leaves. None of them declared a consultation about these CAM with their doctor. Also none of them declared a side effect. Conclusion:Herbal supplements are used by a great majority of diyabetic patients, but none of them were using herbal supplements by physician advice. The use of herbal supplements without physician control may lead to undesirable outcomes for diyabetic patients.
