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    Effect of 1-deamino 8-D-arginine vasopressin spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis
    (Elsevier Ireland Ltd, 2006) Akoglu, Ertap; Goeruer, Sadik; Atik, Esin; Okuyucu, Semsettin; Sanguen, Oezlem
    Objective: To determine any possible adverse effect of 1-deamino 8-D-arginine vasopressin (DDAVP) spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis. Methods: Twenty-two children aged 6-16 enrolled in the study. Epithelial surface cells samples were taken from the nasal mucosa and mucociliary clearance time was calculated before and 1 and 6 months after administration of DDAVP spray. Results: No qualitative changes in the epithelial surface cells and mucociliary clearance time were observed at 1 and 6 months after therapy. Conclusion: Based on the findings of the present study, DDAVP spray can be used for 6 months in children without apparent risk of damage to the epithelial surface cells and mucociliary clearance time. (C) 2006 Elsevier Ireland Ltd. Atl. rights reserved.
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    Prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease
    (Turkish Soc Radiology, 2008) Balcı, Ali; Karazincir, Sinem; Sanguen, Oezlem; Gali, Edip; Daplan, Turgay; Cingiz, Cihangir; Egilmez, Ertugrul
    PURPOSE The aim of this study was to evaluate the type and prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease. MATERIALS AND METHODS A total of 102 patients with sickle cell disease at the Center of Hemoglobinopathy of the Antakya State Hospital were screened for intra-abdominal abnormalities by abdominal ultrasonography (US). Eighty-four patients were homozygous or sickle-cell disease (S/S), and 18 patients were compound heterozygotes for sickle cell-beta thalassemia (S/beta(thal)). At the time of examination, 15.7% (16/102) of patients had undergone gone splenectomy, and 18.6% (19/102) of patients had undergone cholecystectomy. RESULTS The most frequent US findings (expressed as percentages of all patients) were hepatomegaly (71.6%), renal enlargement (30.4%), autosplenectomy (33.3%), cholelithiasis (30.4%) and splenomegaly (17.4%). A bright liver was identified in 6 patients (5.9%), an echogenic pancreas in 4 patients (3.9%), and pancreatic punctate echogenic foci were identified in 5 patients (4.9%). Medullary or diffusely increased renal echogenicity was observed in 16 patients (15.7%). Sonographic findings typical of renal papillary necrosis were observed in one patient with S/S. Periportal lymphadenopathy was detected in 10 (11.9%) of 84 patients of the S/S group, and 2 (11.1%) of 18 patients of S/beta(thal) group. CONCLUSION Abdominal ultrasonographic imaging of patients with sickle cell disease revealed a high prevalence of abdominal abnormalities, especially in solid organs.