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    Öğe
    8-OHdG and hOGG1 levels are as an oxidative DNA damage markers in acne vulgaris treated with isotretinoin
    (Wiley-Blackwell, 2016) Ecevit, H.; Izmirli, M.; Gogebakan, B.; Rifaioglu, E.; Sonmez, D.; Sen, B. Bulbul; Sen, T.
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Does severity of psoriasis increase coronary artery calcification?
    (Wiley-Blackwell, 2013) Sen, B. Bulbul; Rifaioglu, E. N.; Ekiz, O.; Buyukkaya, E.; Sen, N.
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Increased epicardial fat tissue is a marker of subclinical atherosclerosis in patients with psoriasis
    (Wiley-Blackwell, 2013) Sen, B. Bulbul; Atci, N.; Rifaioglu, E. N.; Ekiz, O.; Kartal, I.; Buyukkaya, E.; Kurt, M.
    BackgroundCarotid intima-media thickness (CIMT) is a potential indicator of subclinical atherosclerosis in patients with psoriasis. Epicardial fat thickness (EFT) is proposed as a new cardiometabolic risk factor. ObjectiveTo evaluate the association between EFT and CIMT in patients with psoriasis. MethodsThis was a cross-sectional and observational study; 65 patients with psoriasis and 50 age- and sex- matched control subjects were included. Data about echocardiographic EFT, CIMT, anthropometric measurements and metabolic profile were obtained. ResultsThe EFT and CIMT were significantly increased (7305 vs. 6505mm, P<001; 074011 vs. 060007mm, P<001, respectively) in patients with psoriasis compared with the controls. EFT was significantly correlated with CIMT (r=069, P<001). In a multiple linear regression model in which EFT was independently associated with psoriasis (=045, P<001), age (=033, P=001), CIMT (=050, P<001), body mass index (=025, P=001), high-sensitivity C-reactive protein (=032, P<001) and duration of disease (=034, P=003). ConclusionsWe demonstrated that EFT and CIMT are increased in patients with psoriasis, and that echocardiographic EFT is closely correlated with CIMT in patients with psoriasis. The echocardiographic assessment of EFT may have the potential to be a simple marker of subclinical atherosclerosis and increased cardiovascular risk in patients with psoriasis.