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    Cervical vertebral osteophyte as a rare cause of dysphagia: a report of three cases
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2015) Yetim, Tulin Durgun; Karabacak, Yasemin Bilgin; Bayarogulan, Hanifi; Sengul, Aysen Taslak; Ustun, Nilgun
    Diffuse idiopathic skeletal hyperostosis (ankylosing hyperostosis, Forestier's disease, spondylitis ossificans ligamentosa) is a chronic disease characterized by the widespread spinal osteofit formation due to enchondral ossification of paravertebral ligament and muscles. Treatment is primarily based on dietary changes and anti-inflammatory therapy in diffuse idiopathic skeletal hyperostosis patients suffering from dysphagia. Surgery should be considered in patients with a severe clinical status. In this article, we report three patients and discuss the diagnosis and treatment in the light of literature.
  • Küçük Resim
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    Comparative results of surgical treatment of bullous lung diseases complicated with pneumothorax and the use of polytetrafluoroethylene graft support
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2013) Sengul, Aysen Taslak; Yetim, Tulin Durgun; Buyukkarabacak, Yasemin Bilgin; Basoglu, Ahmet; Gundogdu, Birol
    Background: This study aims to investigate the efficacy of polytetrafluoroethylene (PTFE) graft use in decreasing complications of bullous lung diseases. Methods: Between January 2004 and December 2012, 22 patients with bullous lung disease complicated with spontaneous pneumothorax were included. The patients were divided into two groups. Ten patients in group 1 had heterogeneous emphysematous disease and the 12 patients in group 2 had homogenous emphysematous disease. Both groups underwent muscle-saving thoracotomy. Wedge resection was performed by using stapler. The resection line was supported with an expandable PTFE graft in six patients in group 1 and in five patients in group 2. Treatment results and complications were compared between the groups. Results: Subtype of emphysema was the most important criterion which determined the result of the treatment. Although the use of PTFE graft support had no effect on complications in both emphysema subtypes, it shortened the duration of the chest tube withdrawal and the length of hospital stay. Conclusion: We concluded that the most important criterion which determined the treatment outcome was subtype of emphysema and this led to reduced intubation time and length of hospital stay, although use of PTFE support in both emphysema types had no effect on complications.
  • Küçük Resim
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    Effects of platelet-rich plasma on cartilage regeneration after costal cartilage resection: a stereological and histopathological study
    (Acta Medical Belgica, 2017) Sengul, Aysen Taslak; Buyukkkarabacak, Yasemin Bilgin; Altunkaynak, Berrin Zuhal; Yetim, Tulin Durgun; Altun, Gamze Yayla; Sengul, Bilal; Basoglu, Ahmet
    Background: In cases of congenital chest wall deformities, it is important to maintain the flexibility of the chest wall after rib cartilage resection. In this study, we aimed to determine the regeneration capability of cartilage and the effects of platelet-rich plasma (PRP) on the regeneration process. Methods: A total of 16 four-week-old New Zealand rabbits were used in this study. In the 4th-5th right costal cartilages, the perichondrial sheaths were dissected and costal cartilages were excised. Then, the perichondrial sheaths were closed with absorbable material in the sham group (n = 8), and this was done after replacing PRP in the PRP group (n = 8). The left costal cartilages of the animals were used as controls. The volumes of the costal cartilages and their perichondrial sheaths were estimated using Cavalieri's principle. In addition, the mean numerical densities of the chondroblasts and chondrocytes per square millimetre were estimated using unbiased counting frames. Results: In the PRP and sham groups, the volumes of the cartilages and perichondrial sheaths were higher than those of the control group (p<0.05). The numerical densities of the chondroblasts and chondrocytes increased more in the PRP group than in the sham group (p<0.05). Conclusions: Applying PRP after resection may provide better healing and faster regeneration of cartilage.