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Öğe Atypical presentation of congenital lymphedema(Professional Medical Publications, 2011) Silfeler, Ibrahim; Genens, Mikayir; Sumengen, Dilek; Guler, Salih; Acar, YesimLymphedema, lymphatic fluid is due to an abnormal accumulation in the body in a regional body edema. Congenital lymphedema represents all forms that are clinically evident at birth and accounts for 10-25% of all primary lymphedema cases. The patient was born from consanguineous parents as the first child after two abortion and history of a child death at 14 month of age. On examination the patient had pitting edema at all extremities and abdomen. Lymphangiosintigraphy was performed and no lymph nodes were seen so hereditary primary lymphedema diagnosis was confirmed. Primarily, often caused by a congenital anomaly or dysfunction. As a secondary, acquired disorder is caused by lymphatic flow. Congenital lymphedema, occurs in the first weeks of life. After resolution of the edema the patient was malnourished and had feeding problems. In English literature, congenital lymphedema case with organomegaly, ascites and pitting generalized edema is rarely defined. We report this case because of its unique presentation.Öğe A Case of Chemical Ventriculitis Due to Intraventricular Colistin Treatment(Derman Medical Publ, 2014) Dorum, Bayram Ali; Bal, Tayibe; Ozer, Utku; Aygun, Fatma Deniz; Silfeler, IbrahimNosocomial infections of central nervous system have high mortality, if they are due to Acinetobacter spp., the rate can be as high as 70%. Intraventricular treatment of ventriculitis, caused by Acinetobacter baumannii can be considered as current treatment choice, because of this high mortality. Here in, we report a case of ventriculitis, caused by A. baumannii related to ventriculoperitoneal shunt. We used to treat both with intravenous meropenem, colistin, rifampicin and intraventricular colistin and gentamcin because of persistent ventriculitis after removel of the shunt and multi drug resistant blood flow infection of A. baumannii. The culture of cerebrospinal fluid (CSF) became sterile with intraventricular treatment, but pleocytosis, fever and low glucose level of CSF persisted and chemical ventriculitis was considered to become. We continued the treatment with decreasing the dosage and increasing the interval of drug and were successful both in treatment of the infectious and chemical ventriculitis. The aim of this article is to report the successful treatment of ventriculitis caused by A. baumannii with intraventricular colistin in the fail of intravenous treatment, despite of reversible chemical ventriculitis.Öğe [The case of Henoch-Schönlein Purpura associated with Blastocystis hominis].(2013) Tutanç, Murat; Silfeler, Ibrahim; Ozgür, Tümay; Motor, Vicdan Köksaldi; Kurto?lu, Ahmet IbrahimBlastocystis hominis (B. hominis) is a parasite that often causes gastrointestinal symptoms in patients with immune deficiency and has a controversial pathogenicity in healthy people, although some symptoms are reported outside of the gastrointestinal system in healthy persons. Henoch-Schönlein Purpura (HSP) vasculitis is an acute autoimmune disease characterised by IgA storage of small vessels that is believed to include infectious factors in its aetiology. A 30-month follow-up with a boy diagnosed with HSP being treated with steroid therapy showed that he had recurrent symptoms within two days, and B. hominis was detected in the faecal analysis. His symptoms including rash, abdominal pain, and arthritis improved after treatment with steroid and co-trimaksazol. This paper is the first to present a case of HSP associated with B. hominis.Öğe Closed lip schizencephaly: A case report(Dr Behcet Uz Cocuk Hastaliklari Ve Cerrahisi, 2012) Arica, Vefik; Karakus, Ali; Silfeler, Ibrahim; Arica, Secil Gunher; Altas, Murat; Tutanc, Murat; Basarslan, FatmagulSchizencephaly, has been defined as an almost symmetrical bilateral cleft along the cerebral hemisphere. Clinical findings in patients with schizencephaly depends on the type of clefts (on of off type) and the amount of malformed parenchyma. Incidence of schizencephaly is unclear, while a population-based study performed in the United States reported its incidence as 1.54: 100000. These types of cortical developmental malformations had variable clinical signs depending on the function of the affected area which range widely from mental-motor retardation and epilepsy to focal neurological disorders. We also presented a very rare case with bilateral cleft palate aged 4 years who was referred with recurrent afebrile convulsive episodes and diagnosed as schizencephaly, subependimal heterotopia and temporal lobe epilepsy by cranial MRIÖğe Comparison of Levels in Preterm and Term Neonates Mean Platelet VolumePreterm(Derman Medical Publ, 2013) Silfeler, Ibrahim; Dorum, Bayram Ali; Silfeler, Dilek Benk; Arica, SecilGunherAim: One of the determinants of the functions of platelets and average platelet volume. In our study, preterm newborns with Mean Platelet Volume levels and term newborns with MPV levels are compared. Material and Method: The results of hemogram of a total of 138 newborns (80 preterm and 58 term), which were born in Hospital and have no problem with any other metabolic hematological were evaluated retrospectively. MPV values were compared by statistical analysis. Results: When the MPV values of Term newborns and preterm newborns were compared, The difference was highly statistically significant. Discussion: While the MPV of the sick preterm newborns were assessed, it should not be forgotten that the MPV level of healthy premature babies were higher the MPV level of term newborns. This difference is probably due to the increase in the production of young platelets.Öğe A comparison of misoprostol, controlled-release dinoprostone vaginal insert and oxytocin for cervical ripening(Springer Heidelberg, 2011) Silfeler, Dilek B.; Tandogan, Bulent; Ayvaci, Habibe; Silfeler, Ibrahim; Yenidede, Ilter; Dayicioglu, VedatWe compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming. A total of 218 patients were enrolled to receive between one and three treatments according to physicians' options. The end points were: (1) vaginal delivery or Bishop score a parts per thousand yen8 at the end of 12 h, (2) vaginal delivery by 12 h or difference a parts per thousand yen4 between the initial and 12th hour Bishop scores. Statistical analyses were performed with ANOVA, Krustal Wallis, Scheffe, chi A(2), Fisher, Advanced chi A(2), and Kolmogorov-Smirnov tests. Tukey's HSD was used as a post hoc test. Misoprostol showed statistical significance for the rate of vaginal delivery < 12 h, a parts per thousand yen8 Bishop score at the end of 12 h, and cervical change of a parts per thousand yen4 Bishop scores within 12 h (p = 0.013). Comparison between cases Bishop score < 4 showed that misoprostol is more effective than dinoprostone and oxytocin. Considering Bishop score = 0 cases we calculated no statistical significance.Öğe Determination of hearing levels in patients with Familial Mediterranean Fever(2013) Cevik, Cengiz; Silfeler, Ibrahim; Arica, Vefik; Yengil, Erhan; Akbay, Ercan; Sarac, Tuba; Basarslan, FatmagulObjective: Familial Mediterranean Fever is the most common congenital, periodic fever condition that affects over 100,000 people worldwide. In the literature, there is limited number of studies about hearing levels in children with Familial Mediterranean Fever. In the present study, we aimed to investigate hearing levels and cochlear functions by using Distortion product Otoacoustic Emission and High Frequency Audiometry (250-20,000. Hz) in pediatric patients with Familial Mediterranean Fever. Methods: The study included 62 children with Familial Mediterranean Fever and 27 healthy children with similar age and gender. After otoscopic examination, both groups underwent audiological evaluation including High Frequency Audiometry (250-20,000. Hz) and Distortion product Otoacoustic Emissions. The results obtained were assessed among groups. In addition, these results were compared regarding colchicine use, age at the onset of disease and duration of the diseases in the Familial Mediterranean Fever group. Results: Of the Familial Mediterranean Fever patients, 93.5% were on colchicine therapy and mean duration of colchicine use was 19.9 ± 13.9 months. The mean age at diagnosis was 6.57 ± 2.86 years (min-max: 2-14) and mean duration of disease was 23 ± 17 months (min-max: 6-84). Pure tone audiometry values, and hearing levels between 9000 and 20,000. Hz were similar and within normal range in both groups. The Distortion product Otoacoustic Emissions responses at the frequencies of 1020, 2040, 3000, 4080 and 5040. Hz were similar for both groups. Conclusion: To the best of our knowledge, this is the first study evaluating hearing levels at the frequencies of 18. kHz and 20. kHz in children with Familial Mediterranean Fever in the literature. In children with Familial Mediterranean Fever, Pure tone audiometry values, hearing values obtained at all frequencies from 250 to 20,000. Hz, and Distortion product Otoacoustic Emissions levels were within normal range. Furthermore, hearing levels were found to be similar to those in healthy children. © 2013 Elsevier Ireland Ltd.Öğe Development of acute dystonia in three brothers due to metoclopramide(Isfahan Univ Med Sciences, 2012) Silfeler, Ibrahim; Arica, Vefik; Arica, Secil; Dogan, MuratOne of the agents that cause dystonic reactions is metoclopramide. In this study, we presented three individuals of the same family who were admitted to our hospital while receiving the treatment of metoclopramide because of developing acute dystonic reaction. Appropriate doses of metoclopramide therapy had begun to all brothers with a diagnosis of gastroenteritis. After receiving the first dose of medication, acute dystonia was observed within half an hour in these brothers who used metoclopramide. Thus, if there is a patient who developed acute dystonia in the same family due to metoclopramide, avoiding from use of metoclopramide will be beneficial for other members of the family.Öğe EBV-induced fulminant hepatic failure treated with liver transplantation(Professional Medical Publications, 2010) Silfeler, Ibrahim; Kurnaz, Hilal; Acar, Yesim; Dorum, Bayram Ali; Arica, Vefik; Pekun, FugenViral hepatitis is the leading cause of fulminant hepatitis. Infectious mononucleosis caused by primary infection of EBV is a self-limiting lymphoproliferative disease, and shows concomitant clinical features such as pyrexia, cervical lymphadenopathy, liver dysfunction and hepatosplenomegaly. Even though approximately more than 90 percent of all humans are infected with EBV it rarely causes hepatitis and even if it does it is usually benign and it rarely causes hepatic failure in which the outcome has a high mortality rate. We report a case of fulminant hepatic failure in an immunocompetent 3.5 years old girt caused by primary EBV infection that was treated by orthotropic liver transplantation. This observation emphasizes that EBV must be known as a possible cause of fulminant hepatitis and that liver transplantation is probably the unique therapeutic option to avoid a usually fatal course.Öğe Evaluation of hemoglobinopathy screening results of a six year period in Turkey(Drunpp-Sarajevo, 2012) Arica, Secil Gunher; Turhan, Ebru; Ozer, Cahit; Arica, Vefik; Silfeler, Dilek Benk; Silfeler, Ibrahim; Altun, Ayse BetulBackground and Objectives: Hemoglobinopathies are autosomal recessive inherited diseases more commonly seen in Mediterranean countries. Hereditary blood diseases including Bthalassemia and sickle cell anemia are important health problems. In our study we aimed to analyze the results of the premarital hemoglobinopathy screening test for a 6 years period in Hatay region. Material and Methods: The study sample comprised the couples attending to the Mother and Child Health Care Center in Hatay for premarital hemoglobinopathy screening from 2004 to 2009. Hemoglobin chain analyses of 87.830 couples were evaluated. Results: 175.660 people were screened at total. The prevalence of beta thalassemia trait, sickle cell anemia trait, sickle cell anemia, beta thalassemia major, beta-thalassemia intermedia, alphathalassemia, alpha-thalassemia trait was found as 13.921 (7,9%), 6.074 (3,4%), 631 (0.35%), 132 (0.07%), 118 (0.06%), 9 (0.005%), 150 (0.08%) respectively. 72 newborns with betathalassemia were diagnosed as a result of the marriage of the carrier couples in 6 years. Conclusions: Hatay is a high risk region for beta-thalassemia and sickle cell anemia trait. In countries with high prevalence of hemoglobinopathies, a premarital screening program and counseling is needed to decrease the prevalence.Öğe Fukuyama congenital muscular dystrophy(Professional Medical Publications, 2012) Silfeler, Ibrahim; Arica, Vefik; Davran, Ramazan; Tutanc, Murat; Basarslan, FatmagulMuscular dystrophy is an inherited group of disorders that affects skeletal and many other systems. It is transferred to the next generations with autosomal recessive trait. Congenital muscular dystrophy is a rare disorder characterized by findings emerging from birth. There are 12 different forms of mutation according to defects. Fukuyama syndrome is a rare form of congenital muscular dystrophies in our country. There is FKTN gene mutation. Because it is a rare disease in Turkey, we find this case to be worthy of presentation. After the delivery, patients with recurrent convulsion and hypotonia were admitted to pediatric emergency department. Patients were diagnosed as Fukuyama congenital muscular dystrophy after evaluation based on clinical findings, imaging techniques and gene analysis. Congenital muscular dystrophy should be considered, whereas it is a group of disease in which hypotonia and recurrent convulsions are seen in early infancy period.Öğe Higher frequency of methicillin resistant bacteria in children with familial mediterranean fever(Pakistan Medical Assoc, 2015) Yengil, Erhan; Cevik, Cengiz; Silfeler, Ibrahim; Yula, Erkan; Kurtoglu, Ibrahim Ahmet; Arica, Vefik; Ozer, CahitObjective: To investigate resistant microorganisms in nasal mucosa of children with Familial Mediterranean Fever. Methods: The study was conducted from March to May 2013 at Mustafa Kemal University, Turkey, and comprised children with Familial Mediterranean Fever and healthy controls. All subjects had no history of antibiotic or local and/or systemic steroid use within the preceding 2 weeks. Nasal swab samples were obtained from all the subjects. Strain identification was done by using standard methods. SPSS 13 was used for statistical analysis. Results: Of the 151 subjects in the study, 73(48.34%) were cases and 78(51.65%) were controls. Among the cases, there were 26(35.6%) girls, while among the controls, there were 40(51.3%) girls (p=0.052). The mean age of the cases was 7.78+/-3.34 years (range: 3-15 years), while it was 8.15+/-2.71 years (range: 3-16) among the controls (p=0.208). Methicillin-resistant coagulase-negative staphylococcus and methicillin-resistant staphylococcus aureus were isolated in both the groups. The growth rate of resistant bacteria was 63% (n=46) in the cases, in the controls (p=0.003; odds ratio [OR]: 2.7; 95% confidence interval [CI]: 1.4-5.2). Among the controls, history of hospitalisation increased the risk for the presence of resistant bacteria by 7.7 fold (OR: 7.7; 95%CI: 1.4 - 40.4). Conclusion: Higher rates of resistant bacteria showed that they were at risk of comorbidities related to antibiotic resistance.Öğe The incidence of preeclampsia in intra-Cytoplasmic Sperm injection pregnancies(Professional Medical Publications, 2014) Ulkumen, BurcuArtunc; Silfeler, DilekBenk; Sofuoglu, Kenan; Silfeler, Ibrahim; Dayicioglu, VedatObjective: We aimed to evaluate the association between infertility etiology in Intra-Cytoplasmic Spe rmInjection (ICSI) pregnancies and preeclampsia; besides, we aimed to discuss the effect of the paternalfactor in the pathogenesis of preeclampsia. Hypothesis:We hypothesized that preeclampsia is more common in ICSI pregnancies with male factor. It is known that maternal exposure to paternal sperm cells over a time period has a protective effect against preeclampsia. Male partners with azospermia have no sperm cells in their seminal fluid, whose female partners will not be able to develop some protective immunity against preeclampsia. We hypothesized that the infertile couples with male factor (partner with azoospermia and also oligospermia) would be an ideal model to test the partner-specific protective immunity against preeclampsia, as the women had no chance to develop adequate protective immunity via the partner’s sperm exposure. Methods: This Single-center, retrospective study included 508 infertile couples admitted to our IVF center between January 2001 and March 2008. The data regarding the maternal age, etiology of the infertility, the pregnancy rates, abortus ratio and viable pregnancy rates was collected from the case files. Antenatal complications such as preeclampsia, placenta previa, abruptio placenta, premature rupture of membranes, premature labor, oligohydramnios, gestational diabetes, postmaturity, postpartum complications and neonatal outcomes were evaluated via the file records and phone interviewing. The study population was divided into two main groups according to the etiology of infertility. 301 of the study population (group 1) was infertile due to male factor and 207 of the study population (group 2) was female factor and unexplained infertility cases.Group 1 patients were divided further into two subgroups: group 1a included 56 cases in which TESE (testicular sperm extraction) was used to obtain the sperm cells as the male factor was severe and as there was no sperm cells in seminal fluid. Group 1 b consists of 245oligospermic cases who obtained sperm cells via conventional methods. Results: The mean ages of women in Group one and two were 30.22±5.06 and 31.58±4.36 years respectively (p=0.001). 129 cases (42,8%) from group one and 106 cases (51,2%) from Group two ended in first trimester and early second trimester (<24 gestational weeks) pregnancy loss. In group one, only 172 cases of 301 pregnancies passed over 24 weeks of gestational age, whereas in group two, 101 cases of 207 patients passed over 24 gestational weeks. There was no significant difference between two groups regarding chemical pregnancies and early pregnancy loss (p=0.314). There was no significant difference between the groups regarding placenta previa, gestational diabetes, oligo hydramnios and intrauterine growth retardation. One one pregnancy was 1.5 times more vulnerable for preeclampsia. Conclusion: Pregnancies with azoospermic and oligospermic partners had an increased risk for developing preeclampsia. © 2014, Professional Medical Publications. All Rights Reserved.Öğe The incidence of preeclampsia in Intra-Cytoplasmic Sperm Injection pregnancies(Professional Medical Publications, 2014) Ulkumen, Burcu Artunc; Silfeler, Dilek Benk; Sofuoglu, Kenan; Silfeler, Ibrahim; Dayicioglu, VedatObjective: We aimed to evaluate the association between infertility etiology in Intra-Cytoplasmic Sperm Injection (ICSI) pregnancies and preeclampsia; besides, we aimed to discuss the effect of the paternal factor in the pathogenesis of preeclampsia. Hypothesis: We hypothesized that preeclampsia is more common in ICSI pregnancies with male factor. It is known that maternal exposure to paternal sperm cells over a time period has a protective effect against preeclampsia. Male partners with azospermia have no sperm cells in their seminal fluid, whose female partners will not be able to develop some protective immunity against preeclampsia. We hypothesized that the infertile couples with male factor (partner with azoospermia and also oligospermia) would be an ideal model to test the partner-specific protective immunity against preeclampsia, as the women had no chance to develop adequate protective immunity via the partner's sperm exposure. Methods: This Single-center, retrospective study included 508 infertile couples admitted to our IVF center between January 2001 and March 2008. The data regarding the maternal age, etiology of the infertility, the pregnancy rates, abortus ratio and viable pregnancy rates was collected from the case files. Antenatal complications such as preeclampsia, placenta previa, abruptio placenta, premature rupture of membranes, premature labor, oligohydramnios, gestational diabetes, postmaturity, postpartum complications and neonatal outcomes were evaluated via the file records and phone interviewing. The study population was divided into two main groups according to the etiology of infertility. 301 of the study population (group 1) was infertile due to male factor and 207 of the study population (group 2) was female factor and unexplained infertility cases. Group 1 patients were divided further into two subgroups: group 1a included 56 cases in which TESE (testicular sperm extraction) was used to obtain the sperm cells as the male factor was severe and as there was no sperm cells in seminal fluid. Group 1 b consists of 245oligospermic cases who obtained sperm cells via conventional methods. Results: The mean ages of women in Group one and two were 30.22 +/- 5.06 and 31.58 +/- 4.36 years respectively (p=0.001). 129 cases (42,8%) from group one and 106 cases (51,2%) from Group two ended in first trimester and early second trimester (<24 gestational weeks) pregnancy loss. In group one, only 172 cases of 301 pregnancies passed over 24 weeks of gestational age, whereas in group two, 101 cases of 207 patients passed over 24 gestational weeks. There was no significant difference between two groups regarding chemical pregnancies and early pregnancy loss (p= 0.314). There was no significant difference between the groups regarding placenta previa, gestational diabetes, oligo hydramnios and intrauterine growth retardation. One one pregnancy was 1.5 times more vulnerable for preeclampsia. Conclusion: Pregnancies with azoospermic and oligospermic partners had an increased risk for developing preeclampsia.Öğe Neurobrucellosis as a rare complication of brucellosis: three pediatric case reports(Aves, 2012) Arica, Vefik; Silfeler, Ibrahim; Altas, Murat; Tutanc, Murat; Arica, Secil Gunher; Evirgen, Omer; Davran, RamazanBrucellosis is a major worldwide zoonosis. The disease is endemic in developing countries, particularly in the Mediterranean basin. Brucellosis is frequently seen in Eastern and South-Eastern Anatolia regions in Turkey. Around 18 000 new cases are reported annually in Turkey. Any organ or system of the body can be involved. Brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, sweating, weakness, and headache. Involvement of the central nervous system is rare in brucellosis. Brucella is continuing to be an important health problem especially who live in the countryside. The clinicians usually rule out neurobrucellosis in the differential diagnosis of brucellosis. The three neurobrucellosis cases presented in this paper referred with various non-specific symptoms. Only the first patient was found to have hydrocephalus on CT imaging, while the CT images of the other patients were normal. The second case had a history of consumption of fresh herby cheese, however the other cases had no such history. These three patients were found to have recovered without sequela during their long term follow up. The aim of this presentation is to draw attention to the importance of neurobrucellosis especially in endemic regions including our country. (Turk Arch Ped 2012; 47: 218-21)Öğe Protective Effect of Ellagic Acid on Paraquat-induced Kidney Hazards in Rats(Iranian Soc Nephrolgy, 2017) Silfeler, Ibrahim; Alp, Harun; Dorum, Bayram Ali; Nacar, Emel; Arslan, Selda; Uygur, VeliIntroduction. Paraquat is a commonly used highly toxic herbicide. Despite many studies on detoxification of paraquat, an efficient and safe antidote has not been introduced for toxic cases in human being. The aim of this study was to investigate the effect of ellagic acid (EA) on paraquat-induced kidney hazards in rats. Materials and Methods. Sixty rats were randomly assigned as controls and 5 treatment groups (n = 10 each) receiving EA only, paraquat at doses of 15 mg/kg and 45 mg/kg, and paraquat at the same doses plus EA. Paraquat was intraperitoneally injected and the EA was orally given. Kidney tissues were stained with hematoxylin-eosin for histopathologic investigation. Results. Pathologic scoring showed that paraquat at the higher dose was associated with higher scores than the in the controls, EA group, and the high-dose paraquat group with EA treatment (P < .001 for all comparisons). It was noted that paraquat caused a serious damage in the kidney and the EA treatment significantly reduced the extent of the damage. Conclusions. This study showed the protective effects of EA against paraquat-induced nephrotoxicity histologically. Ellagic acid provided significant improvement in glomerular and tubular structure.Öğe Protective effects of caffeic acid phenethyl ester on dose-dependent intoxication of rats with paraquat(Sage Publications Inc, 2015) Silfeler, Ibrahim; Alp, Harun; Ozgur, Tumay; Evlioglu, Osman; Celik, Murat; Er, Metin; Yilmaz, GulsahPurpose: Paraquat (PQ; 1,1'dimethyl-bipyridilium 4,4'-dichloride), which is used extensively throughout the world, is highly toxic to humans. We aimed to investigate the protective effects of different doses of caffeic acid phenethyl ester (CAPE) on PQ-intoxicated rats. Materials and methods: A total of 80 rats were divided into the following eight groups, comprising 10 rats in each group: group 1: control; group 2: administered with CAPE (10 mu mol/kg); group 3: administered with 15 mg/kg PQ (PQ 15 group); group 4: administered with 30 mg/kg PQ (PQ30 group); group 5: administered with 45 mg/kg PQ (PQ45 group); group 6: administered with 15 mg/kg PQ CAPE; group 7: administered with 30 mg/kg PQ + CAPE and group 8: administered with 45 mg/kg PQ + CAPE. Both PQ and CAPE were injected intraperitoneally. Pancreatic tissue was examined with both haematoxylin and eosin and immunochemical staining. Results: The ratio of the immunohistochemical staining area to the total pancreatic area of the beta cells revealed that statistically significant differences were observed only between the PQ and PQ + CAPE groups (p < 0.05). Discussion: The evaluation of the data suggests that CAPE can be used to prevent acute effects of PQ intoxication.Öğe A rare complication of acute otitis media: A 6-month old infant with peripheral facial paralysis(Dr Behcet Uz Cocuk Hastaliklari Ve Cerrahisi, 2013) Cevik, Cengiz; Tutanc, Murat; Silfeler, Ibrahim; Akbay, Ercan; Alakus, UmmuOtitis media is the second most common infectious disease of childhood, which is defined as clinical presentation that occurs due to inflammation of middle ear. It has been reported that Streptococcus pneumonia, Hemophilus influenzea and Moraxella catarrhalis are the causative agents accounted for acute otitis media (AOM). It is most commonly seen between 6 and 24 months of age. Although AOM is a commonly encountered disease in children, peripheral facial paralysis (PFP) is an uncommon complication of AOM. Most common cause of PFP is Bell's paralysis in children. A child, who had a history of AOM following upper tract infection and presented with PFP (Grade III according to Hause-Brackman classification) on the 3rd day of infection, was admitted to hospital and IV antibiotic therapy was given. One-week steroid therapy was initiated during follow-up period. At the end of 2nd month, PFP was completely recovered by medical treatment. In the present study, we aimed to call attention to a rare complication of AOM, facial paralysis, in this 6-month-old girl.Öğe Reference Values of Serum Cystatin-C for Full-Term and Preterm Neonates in Istanbul(All India Inst Medical Sciences, 2012) Dorum, Sevil; Silfeler, Ibrahim; Dorum, Bayram Ali; Silfeler, Dilek B.; Canbak, Yekta; Say, AysuTo determine the level and distribution of Cystatin C values in full-term and preterm healthy neonates for the purpose of diagnosis and follow-up of renal diseases of the neonates. Eighty-eight newborn infants, including 55 preterm and 33 term born in the authors' hospital having no urinary tract pathology, symptoms or signs during prenatal and postnatal follow-up, were studied . There were 25 neonates born between gestational wk of 28 and 32 (Group 1), 30 neonates born between gestational wk of 33-36 (Group 2) and 33 neonates born after gestational wk of 37 (Group 3). Average cystatin C values were determined to be 1.41 mg/l, 1.22 mg/l and 1.21 mg/l for Group 1, Group 2 and Group 3, respectively. Evalution of cystatin C can be effective for follow-up of renal pathologies, because it is not affected by gender, body weight and muscle mass and has a constant production rate.Öğe The relationship between anemia and accommodative esotropia in children(Isfahan Univ Med Sciences, 2013) Turgut, Fethiye Gulden; Yalcin, Elvan; Silfeler, Ibrahim; Balci, OzlemBackground: Refraction problems, motor disorders, sensorial disorders, physical and psychic traumas of eye may be responsible for development of strabismus. Anemia may cause sensory-neural disorders in children. We investigated the relationship between anemia and accommodative esotropia in children. Materials and Methods: Sixty-four patients with accommodative esotropia were evaluated. This group was identified as patient group (group 1). Eighty-three pediatric patients, who were not esotropia and only had refraction problems, were identified as control group (group 2). The difference between the groups was statistically analyzed evaluating patients for anemia. Results: 33 of 64 patients with accommodative esotropia in group 1 were male, as 43 of 83 patients with refractive error in group 2 were male. The mean age of patients in group 1 and 2 were 6 +/- 3.92 and 6.37 +/- 2.74 (P > 0.05) respectively. There was significant difference between two groups, when mean hemoglobin value of those was compared (P < 0.05). Conclusion: Hb level may affects the accommodative esotropia.