Yazar "Ustun, Ihsan" seçeneğine göre listele
Listeleniyor 1 - 20 / 27
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Calcium Homeostasis During Attack and Remission in Patients With Idiopathic Benign Paroxysmal Positional Vertigo(Lippincott Williams & Wilkins, 2016) Kahraman, Serif Samil; Ozcan, Oguzhan; Arli, Cengiz; Ustun, Ihsan; Erduran, Rana; Akoglu, Ertap; Gokce, CumaliObjective:To evaluate changes in calcium metabolism in patients with idiopathic benign paroxysmal positional vertigo (BPPV) on initial presentation and at the follow-up visit.Subjects and Methods:The study comprised a total of 31 patients aged greater than 18 years who presented at the otorhinolaryngology outpatient clinic of our hospital, newly diagnosed as idiopathic BPPV based on the history compatible with BPPV and positive provocative maneuver (either Dix-Hallpike or Roll test). The first blood sample was obtained on the day of initial presentation when the patient was found to have active unilateral BPPV. After 6 months, a blood sample was again drawn in accordance with the procedure. Blood samples were analyzed for data on 25-hydroxyvitamin D (25(OH)-D), total calcium, parathormone and ionized calcium on initial presentation, and at the follow-up visit.Results:The patients comprised 20 (64.5%) women and 11 (35.5%) men with a mean age of 49.78 years (range, 23-75 years). During an attack a higher prevalence of decreased serum Vitamin D is less than 20ng/ml, was determined (93.5% versus 38.7%). There were statistical differences between the Vitamin D values, parathormone, and corrected by pH ionized calcium in both periods (p<0.05).Conclusion:A statistically significant association was determined between Vitamin D and calcium metabolism in patients with idiopathic BPPV. It can be considered that Vitamin D deficiency and decreased ionized Ca level may be a risk for BPPV, not only in patients with osteoporosis but also in all patients. Very low levels of 25(OH)-D seem to be associated with recurrence of BPPV. The recurrences might possibly be prevented with supplementary Vitamin D especially in those with recurrent idiopathic BPPV but further studies would be necessary to determine this.Öğe A Case of Asymptomatic Riedel Thyroiditis with Follicular Adenoma in a Patient with a Multinodular Goiter: An Unusual Association(Bioscientifica Ltd, 2012) Ozgur, Tumay; Gokce, Hasan; Ustun, Ihsan; Yaldiz, Mehmet; Akin, Mehmet Mustafa; Gokce, CumaliBackground: Riedel's thyroiditis (RT) is a rare inflammatory disease that results in fibrosis of the thyroid gland and invasion to the surrounding structures of the neck. Follicular adenoma (FA) of the thyroid is the most common benign neoplasm of the gland. Patient Findings: A 42-year-old woman was referred to the outpatient clinic due to a multinodular goiter and thyroiditis. The patient was euthyroid and thyroid function tests were within normal limits. Thyroid antibodies (thyroid peroxidase antibody and thyroglobulin antibody) were high. Thyroid ultrasonography showed multiple iso-hypoechoic nodules and thyroiditis. Fine-needle aspiration cytology was performed, and it was consistent with 'suspicious for a follicular neoplasm' according to the Bethesda system. Due to the clinical findings, which included weight loss and sweating, and the cytological results indicative of a follicular neoplasm, the patient underwent a total thyroidectomy. The histopathological diagnosis was RT associated with FA. The patient was started on thyroid hormone (thyroxine) replacement therapy after surgery and was evaluated for additional fibrosis related to RT. Conclusions: To our knowledge, this is the first case of RT associated with FA in an asymptomatic patient with a multinodular goiter and high thyroid antibodies reported in the literature. Copyright (C) 2012 European Thyroid Association Published by S. Karger AG, BaselÖğe Determination of Phthalates Migrating from Plastic Containers into Beverages(Springer, 2015) Ustun, Ihsan; Sungur, Sana; Okur, Ramazan; Sumbul, Ahmet Taner; Oktar, Suleyman; Yilmaz, Nigar; Gokce, CumaliThe determination of phthalates in beverages (soda, lemonade, cola, mineral water) sold in Turkish markets was carried out using gas chromatography-mass spectrometry (GC-MS). The mean phthalate concentrations were determined to be between 0.095 and 0.633 mg/L in soda, 0.018 and 1.219 mg/L in lemonade, 0.019 and 1.123 mg/L in cola, and 0.085 and 0.312 mg/L in mineral water. bis(2-Ethylhexyl) phthalate (DEHP) showed the highest level of migration into beverages. Furthermore, the influence of the type of preservative (sodium benzoate, potassium sorbate, sodium benzoate + potassium sorbate) and storage time were determined.Öğe Diabetic Foot Due to Anaphylactic Shock: A Case Report(Kashan Univ Medical Sciences, 2014) Karakus, Ali; Ozkan, Mustafa; Karcioglu, Murat; Ozden, Raif; Ustun, Ihsan; Caliskan, Koca; Gokce, CumaliIntroduction: Diabetic foot is a clinical disorder, which is commonly seen in patients with diabetes mellitus. It is also the major cause of below knee amputation in the world. There are many underlying causes such as neuropathic, ischemic, and infectious causes for diabetic foot. Local or systemic complications may develop after snake bite. Case Presentation: We reported a very rare case, involving a 78-year-old male admitted to the Emergency Department, who developed anaphylactic shock and diabetic foot after the snake bite. Conclusions: Reviewing the literature, this is the second reported case of snake bite associated with diabetic foot.Öğe The effect of blood glucose regulation on the presence of opportunistic Demodex folliculorum mites in patients with type 2 diabetes mellitus(Sage Publications Ltd, 2013) Gokce, Cumali; Aycan-Kaya, Ozlem; Yula, Erkan; Ustun, Ihsan; Yengil, Erhan; Sefil, Fatih; Rizaoglu, HaticeObjectives To measure the rate of Demodex folliculorum mite infestation in patients with type 2 diabetes mellitus and to investigate if it was related to blood glucose control. Methods Patients with type 2 diabetes were classified according to their glycosylated haemoglobin (HbA(1c)) level into two groups: a well controlled blood glucose group (HbA(1c)7%) and a poorly controlled blood glucose group (HbA(1c)>7%). A standardized skin surface biopsy method was used to determine if the patients had D. folliculorum infestation (>5 mites/cm(2) of skin). Results A total of 69 patients (38 female) were enrolled in the study. Seventeen (24.6%) patients had D. folliculorum infestation. There were no significant differences in age, sex or body mass index between patients with and without D. folliculorum infestations. A significantly higher proportion of patients with poor blood glucose control had D. folliculorum infestation compared with patients with well controlled blood glucose. Conclusions These current findings suggest that poor blood glucose regulation increases the susceptibility to D. folliculorum mite infestation in patients with type 2 diabetes.Öğe Effect of Radioactive Iodine Therapy on Lacrimal Gland Functions in Patients With Hyperthyroidism(Lippincott Williams & Wilkins, 2014) Aydogan, Fusun; Tuzcu, Esra Ayhan; Aydogan, Akin; Akkucuk, Seckin; Coskun, Mesut; Ustun, Ihsan; Gokce, CumaliBackground Radioactive iodine (RAI) therapy is preferred in the treatment of hyperthyroidism because of its effectiveness, noninvasiveness, and low costs. I-131 has been detected in extrathyroidal tissues, such as in gastric mucosa, salivary glands, and lacrimal glands. To the best of our knowledge, there is no publication concerning the effects of RAI therapy for hyperthyroidism on tear production. In the present study, we evaluated whether or not the lacrimal glands are affected after RAI therapy when compared with pretreatment period. Methods The Schirmer and tear break-up time (TBUT) tests were used to assess 32 eyes of 16 patients with conditions that were diagnosed as hyperthyroidism before and at 3 and 6 months after RAI treatment. In addition, pretreatment values of patients were compared with that of controls. It was evaluated whether or not a correlation exists between the results and the dose or iodine uptake values. Results There was no significant difference between pretreatment values of Schirmer and TBUT tests obtained in the patient group and those of the control group (P > 0.05). In the patient group, there was a significant difference between the posttreatment and pretreatment values (P < 0.05). There was a positive correlation between uptake values obtained at 24 hours and the values obtained by TBUT and Schirmer tests on both eyes at 3 and 6 months. At 6 months, the uptake value at 24 hours was 28.83 +/- 60 for both eyes in patients with TBUT test values less than 10, whereas it was 39.25 +/- 7.88 for the right eye and 39.00 +/- 6.85 for the left eyes in patients with TBUT test values greater than 10. The difference was statistically significant (P < 0.05). Conclusions In our study, we concluded that the decrease in mucin and aqueous production occurs due to affected lacrimal glands by RAI therapy; however, this effect is not dose dependent.Öğe Evaluation of mean platelet volume in patients with type 2 diabetes mellitus and blood glucose regulation: a marker for atherosclerosis?(E-Century Publishing Corp, 2014) Ulutas, Kemal Turker; Dokuyucu, Recep; Sefil, Fatih; Yengil, Erhan; Sumbul, Ahmet Taner; Rizaoglu, Hatice; Ustun, IhsanObjective: Platelets have an important role in atherosclerosis and arterial thrombosis. Cardiovascular complication prevalence of type 2 diabetes mellitus (type 2 DM) may be associated with glycosylated hemoglobin (HbA(1c)) and mean platelet volume (MPV). The aim of the study was to investigate if platelets were activated in diabetes and its associated vascular complications by measuring the MPV in the diabetics compared to the non-diabetics, and to determine the correlation of MPV with fasting serum glucose (FSG), HbA(1c) and duration of diabetes in the diabetic patients, respectively. Materials and Methods: The study carried out in 65 patients with type 2 DM and 40 non-diabetic subjects. In addition to non-diabetic patients, all diabetic patients were divided into two groups according to their HbA(1c) levels: group A consisted of patients with HbA(1c) levels <= 7% and group B consisted of patients with HbA(1c) levels >7%. Results: MPV was significantly higher in Group B as compared to both non-diabetics and Group A. MPV had a high positive correlation with HbA(1c) and FSG, as with diabetes duration. It is found that MPV was increased in type 2 DM. Conclusion: Our findings suggested an association between MPV and HbA(1c). Therefore, MPV would be a beneficial prognostic marker of cardio-vascular complications in patients with type 2 DM.Öğe Frequency of Erectile Dysfunction in Metabolic Syndrome Patients(Duzce Univ, 2014) Unal, Mustafa; Aydin, Yusuf; Ustun, Ihsan; Berker, Dilek; Erol, Kutlu; Gul, Kamile; Guler, SerdarPurpose: Metabolic syndrome (MS) is the most important clinical situation which predisposes the endotelial dysfunction and atherosclerosis. Nitric oxid (NO) loss is an important finding in the early stages of endothelial dysfunction. NO deficiency results erectile dysfunction (ED) signs and symptoms. We aim in this study to assess the frequency of the ED in MS patients. Method: This study includes 43 MS patients who fullfill NCEP-ATP III criteria and 29 healthy subjects. A signed permission form was taken from all of the participants. Biochemical and hormonal parameters such as fasting bood glucose (FBG), postprandial glucose (PPG), total testosterone (TT), insulin, high sensitive CRP, total cholesterol (TC), triglyceride (Tg), low density lipoprotein (LDL), high density liporotein (HDL) were measured from the blood which was taken after 12 hours fasting period. ED was evaluated by the questionnaire of International Index of Erectile Function-5 (IIEF-5) which was answered by the included subjects. Insulin resistance was calculated by HOMA-IR method by the formula of FBGxinsulin/405. Results: ED was detected in 65% of the MS group and in 13,8% of the control group. ED was divided into subgroups according to the severity. In MS patients; 18,6% had mild ED, 14% had mild-moderate ED, 14% had moderate ED and 14% had severe ED but in control group only 13,8% of them had mild ED. Although HOMA-IR value was 3,56 +/- 3,45 in MS patients with ED, it was 2,23 +/- 1,72 in patients without ED (p= 0,034). In MS patients with and without ED testosterone levels were measured as 4,5 +/- 1 and 6,1 +/- 1,56, respectively (p< 0,001). Conclusion: ED is highly prevelant in patients with MS and MS patients with ED have low testosterone levels and high HOMA-IR levels which shows insulin resistance.Öğe Gynecomastia: a rare complication of isoretinoin?(Taylor & Francis Ltd, 2013) Ustun, Ihsan; Rifaioglu, Emine Nur; Sen, Bilge Bulbul; Inam, Mehmet Ugur; Gokce, CumaliIsotretinoin is a retinoic acid derivative mostly used in the treatment of cystic acne vulgaris. The adverse effects of isotretinoin are well defined being the major limitation factor for its usage. The decrement of testosteron during isoretinoin treatment is defined in literature. We present a case with 20 years old man who developed gynecomastia after treatment with isotretinoin. To the best of our knowledge, this is the third report of the development of gynecomastia after isotretinoin treatment.Öğe Higher Serum Bisphenol A Levels in Diabetic Hemodialysis Patients(Karger, 2016) Turgut, Faruk; Sungur, Sana; Okur, Ramazan; Yaprak, Mustafa; Ozsan, Muge; Ustun, Ihsan; Gokce, CumaliBackground: Bisphenol A (BPA) has been implicated as an 'endocrine disruptor'. We aimed at exploring the association between serum BPA levels and patient characteristics, particularly the presence of diabetes mellitus, and laboratory parameters in hemodialysis patients. Methods: This study included 47 chronic hemodialysis patients. Patient characteristics were recorded. Blood was drawn before and after hemodialysis session. Serum BPA levels were measured by the high-performance-liquid-chromatography and laboratory parameters were measured by using standard methods. Results: In hemodialysis patients, postdialysis serum BPA levels were significantly higher than predialysis after a single hemodialysis session (5.57 +/- 1.2 vs. 4.06 +/- 0.73, p < 0.0001). Predialysis serum BPA levels were significantly higher in patients with diabetes than non-diabetics (4.4 +/- 0.6 vs. 3.9 +/- 0.7, p = 0.025). No association was found between serum BPA levels and patient characteristics, and particularly laboratory parameters. Conclusion: Serum BPA levels were rising significantly after a single dialysis session. Diabetic hemodialysis patients had higher predialysis serum BPA levels. (C) 2016 S. Karger AG, BaselÖğe How lipid-lowering agents work: The good, the bad, and the ugly(Springer New York, 2014) Turgut, Faruk; Ustun, Ihsan; Go, CumaliHyperlipidemia in the general population is strongly associated with atherosclerotic cardiovascular disease. Dyslipidemia is a common finding in patients with chronic kidney disease (CKD) at all stages. Trial results from the general population may not be applicable to all patients with CKD because they have a different lipid profile with increased atherogenic lipid fractions. Lipid-lowering therapies in these patients may have substantial benefit. Statin therapy is recommended in patients with CKD of any stage if they have elevated serum cholesterol levels. Treatment of dyslipidemia in patients with early stage CKD clearly reduces cardiovascular risk; however, available data do not support a strong nephroprotective role for statins in CKD population. In contrast to the predialysis patient population, statins do not seem to have substantial improvement in cardiovascular outcomes in dialysis patients. Although fibrates can be used to treat mixed dyslipidemia, they need to be used carefully in patients with CKD, and limited available data suggest that fibrates may have a place in reducing cardiovascular risk in patients with mild to moderate CKD. © Springer Science+Business Media New York 2014.Öğe Increased Density of Demodex Folliculorum May be Related to Additional Risk Factors Reply(Acad Medical Sciences I R Iran, 2016) Dokuyucu, Recep; Kaya, Ozlem Aycan; Yula, Erkan; Ustun, Ihsan; Bayram, Fahri; Gokce, Cumali[Abstract Not Available]Öğe Insulin resistance in patients with post-adolescent acne(Wiley-Blackwell, 2015) Balta, Ilknur; Ekiz, Ozlem; Ozuguz, Pinar; Ustun, Ihsan; Karaca, Semsettin; Kacar, Seval Dogruk; Eksioglu, MeralBackgroundPost-adolescent acne has been defined as acne in a patient aged >25years. Acne vulgaris first develops at the onset of puberty as a result of hormonal changes. During puberty, there is a transient decline in insulin sensitivity. We hypothesized that insulin resistance might persist after puberty in patients with post-adolescent acne. ObjectivesThis study was conducted in order to investigate the relationship between post-adolescent acne and insulin resistance. MethodsThe study population comprised 35 patients with post-adolescent acne and 35 healthy control subjects. The parameters measured were fasting blood glucose, insulin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). The homeostasis model assessment of insulin resistance (HOMA-IR) index was calculated for each individual. ResultsNo significant differences were observed between patients with post-adolescent acne and control subjects in fasting blood glucose, fasting insulin, AST, ALT, triglyceride and HDL-C levels, and HOMA-IR index. There were also no correlations between these parameters and the severity of acne. ConclusionsThis study suggests that insulin resistance may not play a major role in the pathogenesis of post-adolescent acne. Hormonal changes, genetic susceptibility, stress, the use of cosmetics, drugs, and environmental factors should be considered in the development of post-adolescent acne.Öğe Investigation of serum bisphenol A, vitamin D, and parathyroid hormone levels in patients with obstructive sleep apnea syndrome(Springer, 2014) Erden, Ersin Sukru; Genc, Sebahat; Motor, Sedat; Ustun, Ihsan; Ulutas, Kemal Turker; Bilgic, Hatice Kayim; Oktar, SuleymanObstructive sleep apnea syndrome (OSAS) is a common health problem, and associated with obesity, metabolic syndrome (MetS), and diabetes. Growing evidence shows that 25-hydroxyvitamin-D-3 (25-OH-D) insufficiency and high parathyroid hormone (PTH) levels may be correlated to glucose intolerance, MetS, obesity, and cardiovascular abnormalities similar to OSAS. Bisphenol A (BPA) is an endocrine disruptor agent which exerts a wide variety of metabolic effects. It has estrogenic activity and its exposure may contribute to weight gain, obesity, impaired glucose metabolism, and the development of diabetes, also similar to OSAS. The aim of this study is to investigate the relationships between OSAS and serum BPA, 25-OH-D, and PTH levels. This study enrolled 128 subjects, with all of the OSAS patients having been diagnosed by polysomnography. The 128 subjects were divided into three groups: a control (n = 43), a moderate OSAS (n = 23) (AHI = 15-30), and a severe OSAS groups (n = 62) (AHI > 30). The serum BPA, 25-OH-D, and PTH levels for each subject were analyzed. 25-OH-D was lower in both OSAS groups, and PTH was higher in the OSAS groups than in the control subjects. The BPA levels were higher in the severe OSAS group than the moderate OSAS and control. There was a positive correlation between the BPA and body mass index, and a negative correlation between the 25-OH-D and BPA levels in all of the individuals. OSAS is related to high BPA and PTH levels, and low vitamin D levels. There is a positive association between BPA levels and OSAS, and the severity of OSAS. These results suggest that the BPA levels may have a role in the pathogenesis of OSAS.Öğe Investigation of vitamin D levels in patients with inactive hepatitis B virus carrier(Acta Medica Mediterranea, 2014) Motor, Sedat; Koksaldi-Motor, Vicdan; Dokuyucu, Recep; Ustun, Ihsan; Evirgen, Omer; Yilmaz, Nigar; Onlen, YusufObjective: The purpose of the present study was to investigate vitamin D levels in inactive hepatitis B virus carriers. Materials and methods: A total of 81 patients with inactive hepatitis B virus carrier state were enrolled at the study. Serum calcium (Ca++), phosphorus (PO4), total protein, albumin, parathormone (PTH) and 25-hydroxy vitamin D (25OHD) were determined. Serum vitamin D concentration was classified as lacking when it was less than 50 nmol/l (20 ng/ml), insufficient when it was 52.5-72.5 nmol/l (21-29 ng/ml), and sufficient when it was more than 75 nmol/l (30-100 ng/ml). Results: The mean 25OHD level was found to be 131.7±50.0 nmol/l. Deficiency and insufficiency was seen in one (1.2 %) and nine (11.1 %) inactive hepatitis B virus carriers, respectively. All the patients have normal serum PTH and albumin levels. Total Ca++ and PO4 were low in ten and eight patients, respectively (p<0.05). Conclusion: Vitamin D may cause the stimulation of antiviral immune response and a preventive effect on necroinflammation and liver fibrosis. Therefore, it may affect course of HBV infection. The new studies with larger sample are needed to research the role of vitamin D in the course of chronic HBV infection, liver failure, cirrhosis, and hepatocellular carcinoma.Öğe INVESTIGATION OF VITAMIN D LEVELS IN PATIENTS WITH INACTIVE HEPATITIS B VIRUS CARRIER(Carbone Editore, 2014) Motor, Sedat; Koksaldi-Motor, Vicdan; Dokuyucu, Recep; Ustun, Ihsan; Evirgen, Omer; Yilmaz, Nigar; Onlen, YusufObjective: The purpose of the present study was to investigate vitamin D levels in inactive hepatitis B virus carriers. Materials and methods: A total of 81 patients with inactive hepatitis B virus carrier state were enrolled at the study. Serum calcium (Ca++), phosphorus (PO4), total protein, albumin, parathormone (PTH) and 25-hydroxy vitamin D (25OHD) were determined. Serum vitamin D concentration was classified as lacking when it was less than 50 nmolll (20 ng/ml), insufficient when it was 52.5-72.5 nmol/l (21-29 ng/ml), and sufficient when it was more than 75 nmol/l (30-100 ng/ml). Results: The mean 25OHD level was found to be 131.7 +/- 50.0 nmol/l. Deficiency and insufficiency was seen in one (1.2 %) and nine (11.1 %) inactive hepatitis B virus carriers, respectively. All the patients have normal serum PTH and albumin levels. Total Ca++ and PO4 were low in ten and eight patients, respectively (p<0.05). Conclusion: Vitamin D may cause the stimulation of antiviral immune response and a preventive effect on necroinflammation and liver fibrosis. Therefore, it may affect course of HBV infection. The new studies with larger sample are needed to research the role of vitamin D in the course of chronic HBV infection, liver failure, cirrhosis, and hepatocellular carcinoma.Öğe Mean platelet volume is influenced by many inflammatory and cardiovascular disorders and cardiovascular risk factors(Springer, 2013) Tuzcu, Esra Ayhan; Arica, Secil; Ilhan, Nilufer; Daglioglu, Mutlu; Coskun, Mesut; Ilhan, Ozgur; Ustun, Ihsan[Abstract Not Available]Öğe Mean platelet volume measurement protocol should be standardized for diabetic retinopathy(Springer, 2013) Tuzcu, Esra Ayhan; Arica, Secil; Ilhan, Nilufer; Daglioglu, Mutlu; Coskun, Mesut; Ilhan, Ozgur; Ustun, Ihsan[Abstract Not Available]Öğe Migrated phthalate levels into edible oils(Taylor & Francis Ltd, 2015) Sungur, Sana; Okur, Ramazan; Turgut, Faruk Hilmi; Ustun, Ihsan; Gokce, CumaliThe determination of phthalates in edible oils (virgin olive oil, olive oil, canola oil, hazelnut oil, sunflower oil, corn oil) sold in Turkish markets was carried out using gas chromatography-mass spectrometry. Mean phthalate concentrations were between 0.102 and 3.863mgL(-1) in virgin olive oil; 0.172 and 6.486mgL(-1) in olive oil; 0.501 and 3.651mgL(-1) in hazelnut oil; 0.457 and 3.415mgL(-1) in canola oil; 2.227 and 6.673mgL(-1) in sunflower oil; and 1.585 and 6.248mgL(-1) in corn oil. Furthermore, the influence of the types of oil and container to the phthalate migration was investigated. The highest phthalate levels were measured in sunflower oil. The lowest phthalate levels were determined in virgin olive oil and hazelnut oil. The highest phthalate levels were determined in oil samples contained in polyethylene terephthalate.Öğe Pituitary apoplexy due to thyroxine therapy in a patient with congenital hypothyroidism(2013) Tutanc, Murat; Altas, Murat; Yengil, Erhan; Ustun, Ihsan; Dolapcioglu, Kenan S.; Balci, Ali; Sefil, FatihA 24-year-old woman was admitted with general weakness, umbilical swelling, developmental delay, speech disorder, constipation, gait problem. Her findings were umbilical hernia, xerosis, dry hair, and short stature. After thyroxine treatment, she also had headache, vomiting, and palpitation, lack of appetite, and sleep disturbance. Pituitary magnetic resonance imaging revealed a heterogeneous mass at the central part of the gland on coronal section and it was interpreted as pituitary apoplexy. In the current case, the patient with congenital hypothyroidism (CH) developed pituitary apoplexy (PA) after thyroxine therapy. Therefore, it is suggested that the complaints were related to PA rather than adrenal insufficiency. Here we describe a case report evaluating PA in a patient with thyrotrophic pituitary adenoma due to CH. To the best of our knowledge, this is the first case in terms of PA associated with CH after thyroxine therapy in the literature.
