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Öğe BENEFITS OF MICROBIAL FERTILIZERS APPLIED AT DIFFERENT GROWTH STAGES ON OIL CONTENT AND QUALITY PROPERTIES OF PEANUT(Soc Field Crop Sci, 2023) Sahin, Cenk Burak; Yilmaz, MustafaMicrobial fertilizer helps the plants grow healthy and stay strong due to including fertilizer and beneficial microorganisms. The purpose of the study was to determine the effects of microbial fertilizers applied in different growth stages on oil content, fatty acid composition and oil quality of peanut (Arachis hypogaea L.). The study was conducted in Osmaniye/Turkey in 2019 and 2020 according to RCBD arranged in split-plots design with 3 replications. The highest oil contents were observed in 150 cc da-1 (53.07%) and beginning bloom + full bloom (53.95%) treatments in studied years. For total unsaturated fatty acid compositions, the highest values were obtained in full bloom (79.49%) and 100 cc da-1 (79.99%) treatments. The highest O/L ratio were observed in full bloom and 100 cc da-1 treatments as 1.72 and 1.68, respectively according to mean of 2-year values. Similar results were seen in IV, and these treatments came forefront with the values 93.83 and 94.52, respectively. As a results of the study, it was concluded that (i) microbial fertilizers had the positive effects on oil content and quality parameters of peanut, (ii) the treatment 100 cc da-1 applied in full bloom may be the optimum selection.Öğe Calorie restriction modulates hippocampal NMDA receptors in diet-induced obese rats(Taylor & Francis Ltd, 2011) Yilmaz, Nigar; Vural, Huseyin; Yilmaz, Mustafa; Sutcu, Recep; Sirmali, Rana; Hicyilmaz, Hicran; Delibas, NamikCalorie restriction (CR) has attracted increased interest since CR enhances lifespan and alters age-related decline in hippocampal-dependent cognitive functions. Obesity is associated with poor neurocognitive outcome including impaired hippocampal synaptic plasticity and cognitive abilities such as learning and memory. N-Methyl-D-aspartate receptors (NMDARs) are linked to hippocampal-dependent learning and memory, which may be stabilized by CR. In the present study, we aimed to establish the effects of CR on NMDARs in CA1 region of hippocampus in obese and non-obese rats. In addition, malondialdehyde (MDA) levels were determined as a marker for lipid peroxidation (LPO) in hippocampus. Four groups were constituted as control group (C, n = 9), obese group (OB, n = 10), obese calorie-restricted group (OCR, n = 9), and non-obese calorie-restricted group (NCR, n = 10). OCR and NCR were fed with a 60% CR diet for 10 weeks. After 10 weeks of CR, the MDA levels significantly decreased in the calorie-restricted groups. Obesity caused significant decreases in NR2A and NR2B subunit expressions in the hippocampus. The hippocampal NR2A and NR2B levels significantly increased in the OCR group compared with the OB group (P < 0.05). In contrast, the hippocampal NR2A and NR2B levels significantly decreased in the NCR group compared with the C group (P < 0.05). Oxidative stress can be prevented by CR, and these data may provide a molecular and cellular mechanism by which CR may regulate NMDAR-mediated response against obesity-induced changes in the hippocampus.Öğe Comparison of Quality and Yield Components of Peanut Market Types Using PCA(Kahramanmaras Sutcu Imam Univ Rektorlugu, 2023) Sahin, Cenk Burak; Yilmaz, Mustafa; Yildiz, Resat; Isler, NecmiThe aim of this study was to compare of agronomic and quality parameters of peanut varieties (Arachis hypogea L.) grown as main crop in Mediterranean Region of Turkiye. Principal component analysis (PCA) was used for evaluating the results of varieties. Field experiments were conducted over during the main crop seasons of the years 2018 and 2019. The experiment was designed as randomized complete block design (RCBD) with three replications. Runner (Georgia Green), Spanish (Florispan) and Virginia market types (Sultan, Brantley, BATEM-Cihangir, BATEM-5025, Arioglu-2003, Halisbey, NC-7, Flower-22, Wilson, NC-V-11, Com, Osmaniye-2005, Gazipasa) peanut varieties were used as plant materials. According to PCA two-year average, PC1, PC2 and PC3 explained about 80% in joined years. Georgia Green could be recommended to achieve high efficiency shelling percentage (73.96%) and pod yield (497.24 kg da-1), and Arioglu-2003 could be the optimum selection on the first quality pod ratio (80.28%) and protein content (28.76%).Öğe DETERMINATION OF OIL QUALITY AND FATTY ACID COMPOSITIONS OF SOME PEANUT (Arachis hypogaea L.) GENOTYPES GROWN IN MEDITERRANEAN REGION(Soc Field Crop Sci, 2022) Sahin, Cenk Burak; Yilmaz, Mustafa; Isler, NecmiThis study was conducted to determine the performance of fifteen peanut lines from India and four peanut varieties (NC-7, Halisbey, Sultan and BATEM-5025) registered in Turkey. The present study was carried out in Osmaniye, which is under Mediterranean climate conditions as main crop season in 2020 and 2021. The experimental design was randomized complete block design (RCBD) with three replications. The highest oil content of peanut was observed in ICGV 10193 (52.16%+/- 0.34), followed by ICGV 10179 (51.58%+/- 0.35) and ICGV 16013 (51.47%+/- 0.35). However, Oleic Acid / Linoleic Acid (OIL) ratio and iodine value are both indicators of peanut shelf life and oil stability. ICGV 15074 and ICGV 16013 came to forefront with high 0/L ratio (9.46 +/- 1.46, 5.44 +/- 0.61) and low iodine value (72.68 +/- 0.60, 76.41 +/- 0.69), respectively. As a result of the study, it was concluded that some Indian peanut lines, mentioned above, can be proper to include breeding program due to their higher oil and oleic acid contents.Öğe Determination of Oil Quality Factors and Fatty Acid Compositions of Some Peanut Varieties(Univ Namik Kemal, 2023) Yilmaz, Mustafa; Sahin, Cenk Burak; Yildiz, Resat; Isler, NecmiThe aim of this study was to determine the oil properties and fatty acid compositions of peanut cultivars (Arachis hypogaea L.) grown as the main crop in the Eastern Mediterranean transition zone of Turkey. The field experiment was conducted at the Oil Seed Research Institute experiment area in the main crop seasons of 2018 and 2019. The experiment was designed according to the randomized complete block design (RCBD) with three replications. Oil ratio, saturated fatty acids (palmitic acid, stearic acid), unsaturated fatty acids (oleic acid, linoleic acid), iodine value, and oleic/linoleic acid ratios were investigated in the experiment. Runner (Georgia Green), Spanish (Florispan), and Virginia market types (Sultan, Brantley, BATEM-Cihangir, BATEM-5025, Arioglu-2003, Halisbey, NC-7, Flower-22, Wilson, NC-V- 11, Com, Osmaniye-2005, Gazipasa) varieties were used as plant materials. As a result of this study, NC-V- 11 (52.23%) cultivar with the highest oil content was determined, followed by Florispan (52.16%), Brantley (52.10%), and Gerogia Green (51.54%). The lowest oil content was obtained from BATEM-Cihangir (44.57%) variety. Brantley variety was found to have the least palmitic acid ratio with 8.04%, while Florispan variety was found the highest with 12.24%. In terms of stearic acid ratios, the lowest value (1.38%) was determined in Com variety, while the highest value (2.91%) was found in Brantley variety. Brantley variety was found to have the highest oleic acid content (71.83%), which is one of the unsaturated fatty acids. Florispan variety had the lowest oleic acid content (43.70%). While Brantley variety had the lowest linoleic acid ratio (9.78%), it was determined that Com variety had the highest linoleic acid ratio (35.77%). The iodine value varied between 78.71-100.71, the lowest value was in Brantley and the highest value was in Com. The oleic acid/linoleic acid ratio was determined to vary between 1.22 and 7.35, the lowest value was in Florispan and the highest value was in Brantley. As a result of the research, it was determined that the variety with the highest oleic acid ratio in the Eastern Mediterranean Transition Zone was Brantley. Peanuts with high oleic acid content are preferred by producers and consumers because they have good quality and extend the shelf life of products producing with them.Öğe Diazinon-induced brain toxicity and protection by vitamins E plus C(Sage Publications Inc, 2012) Yilmaz, Nigar; Yilmaz, Mustafa; Altuntas, IrfanDiazinon (DI) is a widely used pesticide in agriculture, resulting in environmental deleterious effects on neural systems. The current study was performed to investigate the effects of treatment with vitamins E plus C on brain toxicity, which is possibly induced by DI. Twenty-one male rats were divided into three groups (n = 7/group) as follows: (1) control group (C); (2) DI-treated group (DI); (3) DI + vitamins E plus C-treated group (DI + Vit). In order to examine lipid peroxidation and antioxidant status in rats, the level of malondialdehyde (MDA), activities of two free radical scavanging enzymes superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) have been studied in brain of rat. The results showed that treatment with DI induced significant (p < 0.05) increases in the level of serum MDA in rat brain. The vitamins E plus C combination reduced lipid peroxidation in rat brain. The activity of SOD level was significantly higher in DI + Vit group, compared to the control group. GSH-Px, SOD and CAT values were not significantly different in the DI group than in control. Oxidative stress contributes to DI-induced brain toxicity. Our results suggested that vitamins E plus C combination may have a protective effect on DI-induced brain toxicity.Öğe EFFECT OF PLANT REGULATORS ON OIL RATIO AND FATTY ACID COMPOSITION OF PEANUT (Arachis hypogaea L.)(Soc Field Crop Sci, 2023) Yilmaz, Mustafa; Sahin, Cenk BurakPlant growth regulators are organic substances that are synthesized naturally within the plant, and controlled the physiological events, can be transported from where they are formed to other parts of the plants, and can show their effects even at very low concentrations. In this study, it was aimed to determine the effect of different doses of plant growth regulators in different growth stages on oil content and fatty acid compositions of peanut (Arachis hypogaea L.). A total of twelve different treatments were preferred with different chemicals such as gibberallic acid (GA3), mepiquat-chloride (MC), and seaweed (SW) in different growth stages (beginning bloom (BB), full bloom (FB) and beginning bloom + full bloom (BB+FB)). The highest oil content was obtained in MCFB200 (55.46%) treatment, while the lowest was obtained in GA3BB20 (45.44%) treatment. Oleic acid ratio varied from 50.33% to 59.25%, and all treatments were higher than that of the control group. The highest and lowest linoleic acid ratios were observed in SWBBFB100 (26.72%) and GA3FB10 (19.52%) treatments, respectively. MCFB200 and GA3FB10 treatments could be recommended for the highest oil ratio and the highest oleic acid ratio, respectively.Öğe Effects of Venlafaxine and Escitalopram Treatments on NMDA Receptors in the Rat Depression Model(Springer, 2011) Yilmaz, Nigar; Demirdas, Arif; Yilmaz, Mustafa; Sutcu, Recep; Kirbas, Aynur; Cure, Medine Cumhur; Eren, IbrahimDepression may relate to neurocognitive impairment that results from alteration of N-methyl-d-aspartate receptor (NMDAR) levels. Venlafaxine and escitalopram are two drugs commonly used to treat depression. The drugs may affect expression of NMDARs, which mediate learning and memory formation. The aim of the study was to examine whether the effects of venlafaxine and escitalopram treatments are associated with NMDARs in a rat model of depression. Forty male Wistar albino rats were randomly divided into four groups (n = 10) as follows: control group, chronic mild stress group (CMS), venlafaxine (20 mg/kg body weight per day) + CMS, and escitalopram (10 mg/kg body weight per day) + CMS. After induction of depression, a decrease in the concentration of NR2B was observed; venlafaxine treatment prevented the reduction of NR2B expression. Escitalopram treatment did not effect the reduced levels of NR2B resulting from depression. There was no significant difference in NR2A concentration among groups. The present data support the notion that venlafaxine plays a role in maintaining NR2B receptor in experimental depression. It may be possible that treatment with escitalopram has no effect on NMDARs in experimental depression.Öğe Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department(Scientific Publishers of India, 2016) Yaman, Fatih Nazmi; Civelek, Birol; Yavuz, Bunyamin; Yilmaz, Mustafa; Atescelik, Metin; Sahan, Mustafa; Goktekin, Mehmet CagriObjective: To evaluate the relationship between CHA2DS2-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA2DS2- VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA2DS2-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA2DS2-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA2DS2-VASc score being ? 2. The mean age of patients was 68 ± 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA2DS2-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA2DS2-VASc and these markers in high-risk patients with CHA2DS2-VASc score ? 2. © 2016, Scientific Publishers of India. All rights reserved.Öğe Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department.(Allied Acad, 2016) Yaman, Fatih Nazmi; Civelek, Birol; Yavuz, Bunyamin; Yilmaz, Mustafa; Atescelik, Metin; Sahan, Mustafa; Goktekin, Mehmet CagriObjective: To evaluate the relationship between CHA(2)DS(2)-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA(2)DS(2)-VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA(2)DS(2)-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA(2)DS(2)-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA(2)DS(2)-VASc score being >= 2. The mean age of patients was 68 +/- 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA(2)DS(2)-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA(2)DS(2)-VASc and these markers in high-risk patients with CHA(2)DS(2)-VASc score >= 2.Öğe One-Sided Weakness Admitted with Hypokalemic Periodic Paralysis(Derman Medical Publ, 2014) Yaman, Fatih Nazmi; Sahan, Mustafa; Yilmaz, MustafaHypokalemic periodic paralysis (HPP) is a genetic disorder that characterized by recurrent attacks of skeletal muscle weakness with associated hypokalemia which is precipitated by hypotermia, stress, infection, carbonhydrate load, glucose infusion, metabolic alkalosis, general anesthesia, steroids and licorice root. 52-year-old male patient while working in a cold enviroment, began to complain of weakness in the arms and legs. The patient was brought to the emergency department due to the continuation of weakness complaints in the left arm and leg. The neurological examination had 5/5 strength in the upper-right and lowerright extremities, 3/5 strength in the upper-left and lower-left extremities. Serum electrolytes: Potassium: 2.7 mEq/L, 1.9 mEq/L control. There was no evidence of bleeding and infarction in Computerized Brain Tomography and Brain MR. After intravenous infusion of potassium, at the third hour the patient's neurological symptoms resolved completely, patient was mobilized. In this case we present one-sided weakness admitted to the emergency department, the diagnosis of patient with HPP. We aimed to emphasize that this diagnosis should be keeping in mind that among the causes paralysis and delayed diagnose and treatment may be mortal in HPP.Öğe Yield components of peanut as affected by microbial fertilizers and growth stages(Taylor & Francis Inc, 2024) Sahin, Cenk Burak; Yilmaz, MustafaMicrobial fertilizer (MF) provides nutrition to the soil while also improving its structure. Moreover, plants are grown healthy with the help of MF, including beneficial microorganisms and fertilizer. In this study, it was aimed to determine the effects of MFs applied in different growth stages on yield and yield components of peanut (Arachis hypogaea L.). The study was conducted in Osmaniye, Eastern Mediterranean, Turkiye, in 2019 and 2020 according to a split-plot design with three replications. Growth stages of peanut (beginning bloom, full bloom, beginning bloom + full bloom) were placed in main plots and MF doses (0, 50, 100, and 150 cc ha-1) were placed in sub-plots. Consequently, the highest pod yield was observed in 100 and 150 cc ha-1 with the values of 603.67 kg da-1 in 2019 and 590.09 kg da-1 in 2020. For growth stages, full bloom treatments (605.34 kg da-1 in 2019 and 610.81 kg da-1 in 2020) came to the forefront in both years. The treatments of the beginning bloom (23.56% in 2019 and 23.77% in 2020) and 100 cc ha-1 (23.64% in 2019 and 23.88% in 2020) reached the maximum protein content in the studied years. Finally, the present study indicated that MFs had positive effects on yield components of peanut, especially with treatment150 cc ha-1 which increased pod yield and protein content at full bloom stage.
