Yazar "Yuksekdanaci, Seda" seçeneğine göre listele

Listeleniyor 1 - 1 / 1
  • Küçük Resim
    Öğe
    Asymmetric Henry reactions catalyzed by metal complexes of chiral oxazoline based ligands
    (Pergamon-Elsevier Science Ltd, 2013) Aydin, A. Ebru; Yuksekdanaci, Seda
    Chiral oxazolines have been synthesized from norephedrine and pyrrole nitrile or benzoyl chloride and applied to the catalytic asymmetric Henry reactions of p-nitro aldehydes with nitromethane to provide beta-hydroxy nitroalkanols in high conversion (up to 92%). The reaction was then optimized in terms of the metal, solvent, temperature, and amount of chiral ligand. The corresponding catalyst with Cu(OTf)(2) and isopropanol as the solvent gave the best enantioselectivities (up to 84% ee) of the corresponding beta-nitroalkanol for p-nitrobenzaldehyde. (C) 2012 Elsevier Ltd. All rights reserved.