Clinical characteristics and treatment outcomes in patients with urticarial vasculitis

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dc.contributor.authorSerarslan, Gamze
dc.contributor.authorOkyay, Ebru
dc.date.accessioned2024-09-18T20:52:47Z
dc.date.available2024-09-18T20:52:47Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOBJECTIVE: Urticarial vasculitis (UV) is an uncommon disease clinically presenting with pruritic urticarial plaques of the skin. The disease is classified as normocomplementic and hypocomplementemic types according to their complement levels. We aimed to evaluate demographic characteristics, laboratory findings, and response to treatment of patients diagnosed as UV in our clinic. METHODS: Between January 2015 and January 2019, the files of the patients were retrospectively reviewed. Demographic data, clinical features, laboratory findings, suspected triggering factors, disease course, treatment modalities, and treatment results of the patients were recorded. RESULTS: A total of 16 patients (nine males [56.25%], seven females [43.75%]) were included in the study.The mean age at diagnosis was 45.2 +/- 10.4 years and the duration of the disease was 72.1 +/- 62 months. Twelve (75%) patients had angioedema and two (12.5%) patients had residual hyperpigmentation. The most common extracutaneous finding was arthralgia (43.7%). No hypocomplementemia was detected in the patients. The most common abnormal laboratory findings were CRP elevation (37.5%) and ANA positivity (n=4/15, 26.7%). Analgesic and antibiotic drugs use were the most common possible triggering factors for the disease (n=9, 56%). Oral antihistamines, oral corticosteroids, azathioprine, colchicine, dapsone, hydroxychloroquine, doxepin, and omalizumab were among the treatments given to the patients. Complete remission was achieved in three patients. CONCLUSION: Compared with other studies, we found that angioedema was more frequent, postinflammatory hyperpigmentation was lower and long-term treatment was needed to control UV attacks. There are a few studies on UV and we think that more and larger patient groups are needed for standardization of treatment.en_US
dc.identifier.doi10.14744/nci.2020.55476
dc.identifier.endpage517en_US
dc.identifier.issn2148-4902
dc.identifier.issue5en_US
dc.identifier.pmid34909591en_US
dc.identifier.startpage513en_US
dc.identifier.trdizinid508454en_US
dc.identifier.urihttps://doi.org/10.14744/nci.2020.55476
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/508454
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11400
dc.identifier.volume8en_US
dc.identifier.wosWOS:000714065600012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofNorthern Clinics of Istanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNormocomplementemicen_US
dc.subjecturticarial vasculitisen_US
dc.subjecttreatmenten_US
dc.titleClinical characteristics and treatment outcomes in patients with urticarial vasculitisen_US
dc.typeArticleen_US

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