Nitrofurantoin ve fosfomisinin idrar yolu enfeksiyonu etkeni olan e. coli izolatalarına invitro etkiliği

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dc.contributor.authorİnci, Mehmet
dc.contributor.authorYula, Erkan
dc.contributor.authorMotor Köksaldı, Vicdan
dc.contributor.authorDavarcı, Mürsel
dc.contributor.authorDuran, Nizami
dc.contributor.authorKılınç, Çetin
dc.contributor.authorİnci, Melek
dc.date.accessioned2019-07-16T15:54:49Z
dc.date.available2019-07-16T15:54:49Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObject: One of the most frequently isolated microorga- nisms urinary tract infections (UTI) is E. coli. In this study, we aimed to determine susceptibility of E. coli strains isolated from patients with UTI against nitrofurantoin, fosfomycin trometamol and some other frequently used antibiotics. Material and Method: Totally 140 E. coli strains were used in the study. Extended-spectrum beta-lactamase (ESBL) test was performed by double-disc synergy test and antibiotic susceptibility was determined by Kirby- Bauer disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) criteria. Results: It was found that 93.6% of the isolates were susceptible to nitrofurantoin whereas 91.4% of the isolates were susceptible to fosfomycin. Among the other antibiotics, susceptibility was highest to cefepime and ceftazidime and lowest to ampicillin. Regarding ESBL production of the isolates, there was no significant difference between hospital and community acquired infections, and fosfomycin and nitrofurantoin resistance. Conclusion: It was concluded that nitrofurantoin and fosfomycin could be preferred in the empiric treatment of UTIen_US
dc.description.abstractObject: One of the most frequently isolated microorga- nisms urinary tract infections (UTI) is E. coli. In this study, we aimed to determine susceptibility of E. coli strains isolated from patients with UTI against nitrofurantoin, fosfomycin trometamol and some other frequently used antibiotics. Material and Method: Totally 140 E. coli strains were used in the study. Extended-spectrum beta-lactamase (ESBL) test was performed by double-disc synergy test and antibiotic susceptibility was determined by Kirby- Bauer disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) criteria. Results: It was found that 93.6% of the isolates were susceptible to nitrofurantoin whereas 91.4% of the isolates were susceptible to fosfomycin. Among the other antibiotics, susceptibility was highest to cefepime and ceftazidime and lowest to ampicillin. Regarding ESBL production of the isolates, there was no significant difference between hospital and community acquired infections, and fosfomycin and nitrofurantoin resistance. Conclusion: It was concluded that nitrofurantoin and fosfomycin could be preferred in the empiric treatment of UTIen_US
dc.identifier.endpage78en_US
dc.identifier.issn1300-2317
dc.identifier.issue2en_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/1896
dc.identifier.volume30en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.relation.ispartofYeni Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenel ve Dahili Tıpen_US
dc.titleNitrofurantoin ve fosfomisinin idrar yolu enfeksiyonu etkeni olan e. coli izolatalarına invitro etkiliğien_US
dc.title.alternativeIn-vitro efficiency of nitrofurantoin and fosfomycin against E. coli isolates in urinary tract infectionsen_US
dc.typeArticleen_US

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