Üropatojen escherichia coli suşlarının üriner sistem infeksiyonlarının tedavisinde sık kullanılan antibakteriyel ajanlara duyarlılıkları
Loading...
Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Access Rights
info:eu-repo/semantics/openAccess
Abstract
Bu çalışmada Van İpekyolu Devlet Hastanesinde üriner sistem infeksiyon etkenlerinin dağılımı ve en sık izole edilen etken olan Escherichia coli suşlarının antibiyotik duyarlılığının belirlenmesi amaçlanmıştır. Hastane polikliniklerine Ağustos 2008-Haziran 2009 tarihleri arasında başvuran ve üriner sistem infeksiyonu tanısı alan hastaların idrar kültürleri incelenmiştir. Sık izole edilen mikroorganizmalar sırasıyla; Escherichia coli (% 49), Klebsiella (% 13), streptokok (% 9) ve Enterobacter (% 8)’dir. E.coli suşlarının nitrofurantoine % 97, gentamisine % 73, seftriaksona % 67, sefuroksime % 65, siprofloksasin ve ofloksasine % 62, trimetoprim-sülfametoksazole % 39, amoksisilin-klavulanik asite % 35 oranında duyarlı olduğu gözlenmiştir. Sonuç olarak E.coli ile gelişen komplikasyonsuz alt üriner sistem infeksiyonlarının ampirik tedavisinde nitrofurantoinin kullanılabileceği düşünülmüştür. *25.ANKEM Antibiyotik ve Kemoterapi Kongresi’nde sunulmuştur.
In this study, it is aimed to determine the distribution of etiological agents in urinary tract infections in Van Ipek Yolu State Hospital and to determine antibiotic susceptibility of Escherichia coli strains. The urine samples of patients with urinary tract infection admitted to outpatient clinics between August 2008-June 2009 were cultured. The most frequently isolated microorganisms were E.coli (49 %), Klebsiella (13 %), Streptococcus (9 %), Enterobacter (8 %). The results of in vitro antibacterial suspectibiliy testing of E.coli strains to different antibiotics were as below; 97 % of strains were found to be susceptible to nitrofurantoin, 73 % to gentamicin, 67 % to ceftriaxone, 65 % to cefuroxime, 62 % to ciprofloxacin and ofloxacin, 39 % to trimethoprim-sulfamethoxazole and 35 % to amoxicillin-clavulanic acid. It is concluded that in empirical treatment of uncomplicated lower urinary tract infections due to E.coli nitrofurantoin may be used.
In this study, it is aimed to determine the distribution of etiological agents in urinary tract infections in Van Ipek Yolu State Hospital and to determine antibiotic susceptibility of Escherichia coli strains. The urine samples of patients with urinary tract infection admitted to outpatient clinics between August 2008-June 2009 were cultured. The most frequently isolated microorganisms were E.coli (49 %), Klebsiella (13 %), Streptococcus (9 %), Enterobacter (8 %). The results of in vitro antibacterial suspectibiliy testing of E.coli strains to different antibiotics were as below; 97 % of strains were found to be susceptible to nitrofurantoin, 73 % to gentamicin, 67 % to ceftriaxone, 65 % to cefuroxime, 62 % to ciprofloxacin and ofloxacin, 39 % to trimethoprim-sulfamethoxazole and 35 % to amoxicillin-clavulanic acid. It is concluded that in empirical treatment of uncomplicated lower urinary tract infections due to E.coli nitrofurantoin may be used.
Description
Keywords
Farmakoloji ve Eczacılık
Journal or Series
ANKEM Dergisi
WoS Q Value
Scopus Q Value
Volume
24
Issue
4
