Yenidoğanin geçici taki̇pnesi ve konjenital pnömonili olgularda nlo'nun tanisal ve prognosti̇k etkisini̇n i̇ncelenmesi
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Tarih
2022
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Hatay Mustafa Kemal Üniversitesi
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info:eu-repo/semantics/openAccess
Özet
Amaç: Neonatal pnömoni ve YGT yenidoğan yoğun bakım ünitelerine yatışın en sık solunumsal nedenleri arasındadır. Ayırıcı tanısı güç olan bu iki hastalığın erken tanı ve tedavisi için ulaşılması kolay, ucuz ve basit olan; tam kan sayımından elde edilen NLO'nun bu hasta gruplarında tanısal ve prognostik etkisini incelemeyi amaçladık. Yöntem: Çalışmaya Mayıs 2021-Haziran 2022 tarihleri arasında Hatay Mustafa Kemal Üniversitesi Hastanesi Yenidoğan Yoğun bakım ünitesinde YGT veya neonatal pnömoni tanısı ile takip edilen 120 hasta ve 120 sağlıklı yenidoğan bebek olmak üzere toplam 240 yenidoğan dahil edildi. Çalışma prospektif olarak planlandı. Hastaların NLO oranları ile hastanede yatış süresi, antibiyotik kullanım durumu, antibiyotik kullanım süresi, doğum haftası, doğum kilosu, cinsiyeti ve laboratuvar bulguları incelendi. Bulgular: Bizim çalışmamızda NLO oranının hasta grupta 0.84 (0.62), kontrol grubunda 1.31 (0.74) olduğu tespit edildi (p<0.001). Bu oranın hasta grubunda kontrol grubuna göre daha düşük olduğu saptandı. Her iki hasta grubunda ise NLO açısından anlamlı fark olmadığı görüldü. NLO değeri düşük hastaların daha uzun süre oksijen desteği aldığı ve daha uzun süre yattığı gösterildi. NLO değerinin düşüklüğü ile yatış süresinin ve oksijen destek süresinin uzaması arasında ilişki olduğu gösterildi. Sonuç: Yenidoğan yoğun bakım ünitesinde YGT veya neonatal pnömoni tanısı ile takip edilen hastalarda NLO'nun erken tanı ve tedavide faydalı olabileceği, hastalığın prognozu hakkında fikir verebileceği kanısındayız.
Aim: Neonatal pneumonia and TTN are among the most common respiratory causes of hospitalization in neonatal intensive care units. Easy to access, cheap and simple for the early diagnosis and treatment of these two diseases, which are difficult to differentiate; we aimed to examine the diagnostic and prognostic effect of NLR obtained from complete blood count in these patient groups. Methods: A total of 240 newborns,120 healthy newborns and 120 patients who were followed up with the diagnosis of YGT or neonatal pneumonia in the Neonatal Intensive Care Unit of Hatay Mustafa Kemal University Training and Research Hospital between May 2021 and June 2022 were included in the study. The study was planned prospectively. NLR rates of the patients, duration of hospitalization, antibiotic use, duration of antibiotic use, week of birth, b,rth weight, gender and laboratory findings were analyzed. Results: In our study, the NLR rate was found to be 0.84 (0.62) in the patient group, 1.31 (0.74) in the control group, and it was found to be lower in the patient group than in the control group (p<0.001). In the patient group, there was no significant difference in terms of NLR. It has been shown that patients with low NLR values received longer oxygen support and were hospitalized for longer. It has been shown that there is a relationship between low NLR value and prolonged hospitalization and oxygen support time. Conclusion: We believe that NLR may be useful in early diagnosis and treatment in patients followed up in the neonatal intensive care unit with the diagnosis of TTN or neonatal pneumonia, and may provide an idea about the prognosis of the disease.
Aim: Neonatal pneumonia and TTN are among the most common respiratory causes of hospitalization in neonatal intensive care units. Easy to access, cheap and simple for the early diagnosis and treatment of these two diseases, which are difficult to differentiate; we aimed to examine the diagnostic and prognostic effect of NLR obtained from complete blood count in these patient groups. Methods: A total of 240 newborns,120 healthy newborns and 120 patients who were followed up with the diagnosis of YGT or neonatal pneumonia in the Neonatal Intensive Care Unit of Hatay Mustafa Kemal University Training and Research Hospital between May 2021 and June 2022 were included in the study. The study was planned prospectively. NLR rates of the patients, duration of hospitalization, antibiotic use, duration of antibiotic use, week of birth, b,rth weight, gender and laboratory findings were analyzed. Results: In our study, the NLR rate was found to be 0.84 (0.62) in the patient group, 1.31 (0.74) in the control group, and it was found to be lower in the patient group than in the control group (p<0.001). In the patient group, there was no significant difference in terms of NLR. It has been shown that patients with low NLR values received longer oxygen support and were hospitalized for longer. It has been shown that there is a relationship between low NLR value and prolonged hospitalization and oxygen support time. Conclusion: We believe that NLR may be useful in early diagnosis and treatment in patients followed up in the neonatal intensive care unit with the diagnosis of TTN or neonatal pneumonia, and may provide an idea about the prognosis of the disease.
Açıklama
Anahtar Kelimeler
Çocuk Sağlığı ve Hastalıkları, Child Health and Diseases, Yenidoğanın Geçici Takipnesi, Neonatal pnömoni, Nötrofil Lenfosit Oranı, Transient Tachypnea of Newborn, Neonatal pneumonia, Neutrophil Lymphocyte Ratio
