Thrombotic thrombocytopenic purpura in a patient with brucella infection is highly responsive to combined plasma infusion and antimicrobial therapy
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Dosyalar
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Karger
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion. Case Presentation and Intervention: A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5 degrees C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment. Conclusion: This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP. Copyright (C) 2007 S. Karger AG, Basel.
Açıklama
Anahtar Kelimeler
thrombotic thrombocytopenic purpura, brucellosis, antimicrobial treatment
Kaynak
Medical Principles and Practice
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
16
Sayı
4