Thrombotic thrombocytopenic purpura in a patient with brucella infection is highly responsive to combined plasma infusion and antimicrobial therapy

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dc.contributor.authorErdem, Fuat
dc.contributor.authorKiki, Ilhami
dc.contributor.authorGuendogdu, Mehmet
dc.contributor.authorKaya, Hasan
dc.date.accessioned2024-09-18T20:59:25Z
dc.date.available2024-09-18T20:59:25Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion. Case Presentation and Intervention: A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5 degrees C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment. Conclusion: This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP. Copyright (C) 2007 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000102159
dc.identifier.endpage326en_US
dc.identifier.issn1011-7571
dc.identifier.issue4en_US
dc.identifier.pmid17541302en_US
dc.identifier.scopus2-s2.0-34249826349en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.1159/000102159
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12561
dc.identifier.volume16en_US
dc.identifier.wosWOS:000247028400014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectthrombotic thrombocytopenic purpuraen_US
dc.subjectbrucellosisen_US
dc.subjectantimicrobial treatmenten_US
dc.titleThrombotic thrombocytopenic purpura in a patient with brucella infection is highly responsive to combined plasma infusion and antimicrobial therapyen_US
dc.typeArticleen_US

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