Epicardial fat thickness is associated with oxidative stress index in cardiac syndrome X

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dc.authorid0000-0002-5065-3283en_US
dc.contributor.authorÖzbiçer, Süleyman
dc.contributor.authorKalkan, Gülhan
dc.contributor.authorGür, Mustafa
dc.contributor.authorTopuz, Mustafa
dc.contributor.authorKaypaklı, Onur
dc.contributor.authorKoç, Mevlüt
dc.contributor.authorErel, Özcan
dc.date.accessioned2021-12-14T12:17:18Z
dc.date.available2021-12-14T12:17:18Z
dc.date.issued2020en_US
dc.departmentTayfur Ata Sökmen Tıp Fakültesien_US
dc.description.abstractAbstractAim: We aimed to investigate the relationship between oxidative parameters- total oxidant status (TOS), total antioxidant capacity (TAC), and oxidative stress index (OSI)- and EFT in patients with CSX. Without clinically significant coronary artery disease, cardiac syndrome X (CSX) is characterized by cardiac ischemia, and chest pain. However, there is some evidence about increased oxidative stress in CSX patients; the relationship between oxidative stress parameters and epicardial fat thickness (EFT) is not well established in this population.Material and Methods: : One hundred and twenty-two patients with normal coronary arteries (73 female, 49 males, mean age 56.71 ± 10.69 years) were enrolled in the study. The study population was divided into two groups according to their OSI. Oxidative stress index below the median was defined as the OSI low group and equal or higher than the median was defined as the OSI high group.Results: EFT was higher in the high OSI group than the low OSI group (6 (3.9 – 8.9) vs. 5.4 (0.56 – 7.2), p= 0.032). In bivariate correlation analysis EFT was positively correlated with OSI and TOS (r=0.242, p=0.036 and r=0.234, p=0.025 respectively). In binary logistic regression analysis, EFT was found to be an independent predictor of OSI.Conclusion: : In our study, EFT was independently associated with OSI in CSX patients. This finding suggests that EFT may be a marker of increased oxidative stress in CSX.en_US
dc.identifier.citationOZBİCER S,KALKAN G,GUR M,TOPUZ M,KAYPAKLİ O,KOÇ M,EREL O (2020). Epicardial fat thickness is associated with oxidative stress index in cardiac syndrome X. Annals of Medical Research, 27(4), 1228 - 1233. Doi: 10.5455/annalsmedres.2019.11.769en_US
dc.identifier.doi10.5455/annalsmedres.2019.11.769en_US
dc.identifier.endpage1233en_US
dc.identifier.issn2636-7688
dc.identifier.issue4en_US
dc.identifier.startpage1228en_US
dc.identifier.trdizinid362479en_US
dc.identifier.urihttps://dx.doi.org/10.5455/annalsmedres.2019.11.769
dc.identifier.urihttps://hdl.handle.net/20.500.12483/3353
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherİnönü Üniversitesien_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Başka Kurum Yazarıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidantsen_US
dc.subjectMicrovascular dysfunctionen_US
dc.subjectOxidative stressen_US
dc.titleEpicardial fat thickness is associated with oxidative stress index in cardiac syndrome Xen_US
dc.typeArticleen_US

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