Effects of Oxidative Stress-Related Major Molecular Parameters on Milk Composition in Weaning Period of Damascus Goats [1]

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dc.authoridOzkan, Huseyin/0000-0001-5753-8985
dc.authoridKaya, Ufuk/0000-0002-4805-0993
dc.contributor.authorOzkan, Huseyin
dc.contributor.authorDalkiran, Sevda
dc.contributor.authorKaraaslan, Irem
dc.contributor.authorKaya, Ufuk
dc.contributor.authorCamdeviren, Baran
dc.contributor.authorYuksel, Murat
dc.contributor.authorYakan, Akin
dc.date.accessioned2024-09-18T20:13:29Z
dc.date.available2024-09-18T20:13:29Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe weaning process in goat breeding is applied in various methods depending on the breeding administration. In this study, blood and milk samples have been collected from Damascus goats at the weaning day (postpartum 105th day-weaned day) and a week later (post-weaned day). In addition to determining cortisol and MDA in plasma, COX-2 and NFE2L2 activities have been investigated both mRNA and protein levels from leucocytes and plasma. Compositional parameters of milk have also been analyzed and the possible relations between studied parameters have been investigated. While expression levels of COX-2 and SCC of milk decreased, pH of milk was increased in post-weaned day samples. The MDA, FFDM, protein, lactose and freezing point were decreased in the post-weaned day. Milk fat was negatively correlated with NFE2L2, and milk protein had positively correlated with SCC and FFDM. On the other hand, lactose was positively correlated with FFDM and protein. In addition, most of the compositional parameters positively correlated with a freezing point; they were negatively correlated with electrical conductivity. According to the results obtained from the study, it is thought that the decrease in milk fat in goats may be an indicator of increased oxidative stress in lactating goats due to the increase in NFE2L2 protein, which has a central role in the antioxidant response.en_US
dc.description.sponsorshipScientific Research Council of Hatay Mustafa Kemal University [21.GAP.023]en_US
dc.description.sponsorshipThis work was financially supported by Scientific Research Council of Hatay Mustafa Kemal University with 21.GAP.023 project number.en_US
dc.identifier.doi10.9775/kvfd.2022.27101
dc.identifier.endpage377en_US
dc.identifier.issn1300-6045
dc.identifier.issn1309-2251
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85134561865en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage371en_US
dc.identifier.trdizinid532214en_US
dc.identifier.urihttps://doi.org/10.9775/kvfd.2022.27101
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/532214
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9219
dc.identifier.volume28en_US
dc.identifier.wosWOS:000800606600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOX-2en_US
dc.subjectDamascus goaten_US
dc.subjectGene expressionen_US
dc.subjectNFE2L2en_US
dc.subjectWeaning in goatsen_US
dc.titleEffects of Oxidative Stress-Related Major Molecular Parameters on Milk Composition in Weaning Period of Damascus Goats [1]en_US
dc.typeArticleen_US

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