Adneksiyal kitle saptanan hastalarda malignite riskinin preoperatif araştırılması
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Dosyalar
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Hatay Mustafa Kemal Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Adneksiyal kitle saptanan hastalarda malignite riskinin preoperatif araştırılması ve yöntemlerin etkinliklerinin karşılaştırılması Materyal ve metod: MKÜ Tıp Fakültesi Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniginde adneksiyal kitle nedeni ile opere edilen 135 olgu çalışmaya dahil edilmiştir. Çalısmada kullanılan parametreler; bimanuel pelvik muayene, tumör belirteçleri, ultrasonografi, renkli doppler ultrasonografi, trombosit sayısı idi. Preoperatif dönemde değerlendirmeye alınan bu parametreler histopatoloji sonuçları ile karşılaştırıldı. Bulgular: Çalışmaya alınan olguların parametreleri değerlendirildiğinde; Pelvik muayenenin sensitivitesi % 52,9, spesifisitesi % 78, PPV % 25,7 ve NPV: % 92 bulundu. CA 125'in sensitivitesi % 88,2, spesifisitesi % 72,9, PPV % 31,9, NPV % 97,7 bulundu. Ultrasonografinin sensitivitesi % 70,6, spesifisitesi % 97,5, PPV % 80, NPV % 95,8 bulundu. Renkli doppler ultrasonografinin sensitivitesi % 70,6, spesifisitesi % 88,1, PPV % 46,1, NPV % 95,4 bulundu. Trombosit sayımının sensitivitesi % 76,5, spesifisitesi % 61,9, PPV % 22,4, NPV % 94,8 bulundu. Sonuç: Kullandığımız parametrelerin hiçbiri adneksiyal kitlelerin malign-benign ayrımında tek başlarına kullanılabilecek etkinliğe sahip değildir. Anahtar sözcükler: Adneksiyal kitle, Benign malign ayrımı, Preoperatif Tanı
Objective: To evaluate the malignity risk of adnexal masses preoperatively and to compare effectiveness of diagnostic methods Material and method: 135 cases operated for adnexal mass in Obstetrics and Gynecology Clinic of MKU Medicine Faculty Education and Research Hospital, Hatay, Turkey. Bimanual pelvic examination, tumour markers, ultrasonography, color doppler ultrasonography, and platelet count were evaluated parameters in the study. These parameters evaluated in preoperative period and then compared with postoperative histopathology results. Findings: When parameters of cases included in the study were evaluated, for pelvic examinition, sensitivity was 52,9 %, spesificity was 78 %, positive predictive value was 25,7 %, negative predictive value was 92%. For CA-125, sensitivity was 88,2 %, specificity was 72,9 %, positive predictive value was 31,9 %, negative predictive value was 97,7%. For ultrasonography, sensitivity was 70,6 %, specificity was 97,5 %, positive predictive value was 80 %, negative predictive value was 95,8 % . For color doppler ultrasonography, sensitivity was 70,6 %, specificity was 88,1 %, positive predictive value was 46,1 %, negative predictive value was 95,4 %. For platelet counts, sensitivity was 76,5%, specificity was 61,9 %, positive predictive value was 22,4 %, negative predictive value was 94,8 %. Conclusion: None of the parameters we used, have enough effectivity alone for differentiating malign-benign adnexal mass. Key words: Adnexial mass, Malign benign discrimination, Preoperative diagnosis
Objective: To evaluate the malignity risk of adnexal masses preoperatively and to compare effectiveness of diagnostic methods Material and method: 135 cases operated for adnexal mass in Obstetrics and Gynecology Clinic of MKU Medicine Faculty Education and Research Hospital, Hatay, Turkey. Bimanual pelvic examination, tumour markers, ultrasonography, color doppler ultrasonography, and platelet count were evaluated parameters in the study. These parameters evaluated in preoperative period and then compared with postoperative histopathology results. Findings: When parameters of cases included in the study were evaluated, for pelvic examinition, sensitivity was 52,9 %, spesificity was 78 %, positive predictive value was 25,7 %, negative predictive value was 92%. For CA-125, sensitivity was 88,2 %, specificity was 72,9 %, positive predictive value was 31,9 %, negative predictive value was 97,7%. For ultrasonography, sensitivity was 70,6 %, specificity was 97,5 %, positive predictive value was 80 %, negative predictive value was 95,8 % . For color doppler ultrasonography, sensitivity was 70,6 %, specificity was 88,1 %, positive predictive value was 46,1 %, negative predictive value was 95,4 %. For platelet counts, sensitivity was 76,5%, specificity was 61,9 %, positive predictive value was 22,4 %, negative predictive value was 94,8 %. Conclusion: None of the parameters we used, have enough effectivity alone for differentiating malign-benign adnexal mass. Key words: Adnexial mass, Malign benign discrimination, Preoperative diagnosis
Açıklama
Anahtar Kelimeler
Kadın Hastalıkları ve Doğum, Obstetrics and Gynecology
