MR imaging properties of breast cancer molecular subtypes

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Küçük Resim

Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Verduci Publisher

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

OBJECTIVE: In this study, we aim at investigating the magnetic resonance (MR) imaging features of molecular subtypes, according to the BIRADS Atlas. PATIENTS AND METHODS: The preoperative MRI examinations of 104 breast cancer patients were reviewed retrospectively using the 5th Edition Breast Imaging-Reporting and Data System (BI-RADS) Atlas. According to BIRADS. cases were classified as mass or nonmass enhancement. Background parenchymal enhancements of the cases were evaluated. The population was examined for shape. contour, enhancement characteristics of masses. distribution and internal enhancement patterns of nonmass enhancements, background parenchymal enhancement. multifocal/multicentric (MFMS) status, presence of axillary LAP. ADC values, and kinetic aspects. The Kruskal-Wallis and Chisquare tests were used to explore the connection between molecular subtypes and MR data. RESULTS: The link between molecular subtypes and mass/non-mass enhancement was discovered to be statistically significant (p=0.007). The shape (p=0.001) and contour (p=0.001) properties of the masses were observed to differ depending on the molecular subtypes. The Luminal types were usually irregularly shaped with irregular/spiculated contours, whereas the HER-2 (+) and Triple (-) subtypes were mostly oval/round with smooth contours. The subtype with the highest non-mass enhancement rate (70%) was HER2 (+). Axillary lymphadenopathy was most common (64.3%) in the Triple (-) subtype (p=0.033). CONCLUSIONS: According to the BIRADS Atlas, molecular subtypes exhibit a wide range of imaging properties in MR in our study.

Açıklama

Anahtar Kelimeler

BI-RADS, Breast cancer, Magnetic resonance, Molecular subtype, MRI

Kaynak

European Review For Medical and Pharmacological Sciences

WoS Q Değeri

Q2

Scopus Q Değeri

Q2

Cilt

26

Sayı

11

Künye