MR imaging properties of breast cancer molecular subtypes

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dc.contributor.authorSEYFETTIN, A.
dc.contributor.authorDEDE, I.
dc.contributor.authorHAKVERDI, S.
dc.contributor.authorASIG, B. D. U. Z. E. L.
dc.contributor.authorTEMIZ, M.
dc.contributor.authorKARAZINCIR, S.
dc.date.accessioned2024-09-18T20:04:24Z
dc.date.available2024-09-18T20:04:24Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOBJECTIVE: In this study, we aim at investigating the magnetic resonance (MR) imaging features of molecular subtypes, according to the BIRADS Atlas. PATIENTS AND METHODS: The preoperative MRI examinations of 104 breast cancer patients were reviewed retrospectively using the 5th Edition Breast Imaging-Reporting and Data System (BI-RADS) Atlas. According to BIRADS. cases were classified as mass or nonmass enhancement. Background parenchymal enhancements of the cases were evaluated. The population was examined for shape. contour, enhancement characteristics of masses. distribution and internal enhancement patterns of nonmass enhancements, background parenchymal enhancement. multifocal/multicentric (MFMS) status, presence of axillary LAP. ADC values, and kinetic aspects. The Kruskal-Wallis and Chisquare tests were used to explore the connection between molecular subtypes and MR data. RESULTS: The link between molecular subtypes and mass/non-mass enhancement was discovered to be statistically significant (p=0.007). The shape (p=0.001) and contour (p=0.001) properties of the masses were observed to differ depending on the molecular subtypes. The Luminal types were usually irregularly shaped with irregular/spiculated contours, whereas the HER-2 (+) and Triple (-) subtypes were mostly oval/round with smooth contours. The subtype with the highest non-mass enhancement rate (70%) was HER2 (+). Axillary lymphadenopathy was most common (64.3%) in the Triple (-) subtype (p=0.033). CONCLUSIONS: According to the BIRADS Atlas, molecular subtypes exhibit a wide range of imaging properties in MR in our study.en_US
dc.identifier.endpage3848en_US
dc.identifier.issn1128-3602
dc.identifier.issue11en_US
dc.identifier.pmid35731053en_US
dc.identifier.scopus2-s2.0-85133101110en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3840en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8146
dc.identifier.volume26en_US
dc.identifier.wosWOS:000820248700008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBI-RADSen_US
dc.subjectBreast canceren_US
dc.subjectMagnetic resonanceen_US
dc.subjectMolecular subtypeen_US
dc.subjectMRIen_US
dc.titleMR imaging properties of breast cancer molecular subtypesen_US
dc.typeReview Articleen_US

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