EFFICACY OF CAPSAICIN ON CELL ADHESION AND INVASION OF ORAL PATHOGENS
Yükleniyor...
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Inst. Nat. Cercetare-Dezvoltare Text. Pielarie
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Streptococcus pyogenes, Streptococcus mutans, and Candida albicans are important human pathogens and their infections in the mouth, mouth, and throat are important. Prophylaxis against oral and respiratory tract infections is of great importance in terms of both reducing the use of antibiotics and lowering the infection frequency. This study investigated the antimicrobial activity of Capsaicin against S. mutans, C. albicans, and S. pyogenes. Non-cytotoxic concentration of Capsaicin was determined in the Vero cell line by the MTT method. Efficacy studies were performed within these determined non-cytotoxic concentrations. The efficacy of single and different combinations of these three biological components on cell adhesion and invasion. The non-toxic concentration of capsaicin on Vero cells was <1.35 ?g/ml. Capsaicin exhibited significant antimicrobial activity against S. pyogenes, S. mutans, and C. albicans. Moreover, capsaicin was statistically significantly effective against host cell adhesion and invasion against S. mutans, S. pyogenes and C. albicans compared to the control group. The results showed that capsaicin is a highly potent antibacterial agent against S. pyogenes, and S. mutans, as well as an important prophylactic agent for fungal infections. As a result, we think that capsaicin is a useful molecule for the provision and maintenance of both respiratory diseases and oral health. © 2022 Toate drepturile asupra acestei edi?ii sunt rezervate editorilor.
Açıklama
9th International Conference on Advanced Materials and Systems, ICAMS 2022 -- 26 October 2022 through 28 October 2022 -- Bucharest -- 292469
Anahtar Kelimeler
C. albicans, lozenge, proliaxia, S. aureus, S. pyogenes, throat infection
Kaynak
ICAMS Proceedings of the International Conference on Advanced Materials and Systems
WoS Q Değeri
Scopus Q Değeri
N/A
