EFFICACY OF CAPSAICIN ON CELL ADHESION AND INVASION OF ORAL PATHOGENS

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dc.authorscopusid57205663708
dc.authorscopusid35612683100
dc.contributor.authorTek, Erhan
dc.contributor.authorDuran, Nizami
dc.date.accessioned2024-09-19T15:41:17Z
dc.date.available2024-09-19T15:41:17Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description9th International Conference on Advanced Materials and Systems, ICAMS 2022 -- 26 October 2022 through 28 October 2022 -- Bucharest -- 292469en_US
dc.description.abstractStreptococcus pyogenes, Streptococcus mutans, and Candida albicans are important human pathogens and their infections in the mouth, mouth, and throat are important. Prophylaxis against oral and respiratory tract infections is of great importance in terms of both reducing the use of antibiotics and lowering the infection frequency. This study investigated the antimicrobial activity of Capsaicin against S. mutans, C. albicans, and S. pyogenes. Non-cytotoxic concentration of Capsaicin was determined in the Vero cell line by the MTT method. Efficacy studies were performed within these determined non-cytotoxic concentrations. The efficacy of single and different combinations of these three biological components on cell adhesion and invasion. The non-toxic concentration of capsaicin on Vero cells was <1.35 ?g/ml. Capsaicin exhibited significant antimicrobial activity against S. pyogenes, S. mutans, and C. albicans. Moreover, capsaicin was statistically significantly effective against host cell adhesion and invasion against S. mutans, S. pyogenes and C. albicans compared to the control group. The results showed that capsaicin is a highly potent antibacterial agent against S. pyogenes, and S. mutans, as well as an important prophylactic agent for fungal infections. As a result, we think that capsaicin is a useful molecule for the provision and maintenance of both respiratory diseases and oral health. © 2022 Toate drepturile asupra acestei edi?ii sunt rezervate editorilor.en_US
dc.identifier.doi10.24264/icams-2022.III.19
dc.identifier.endpage374en_US
dc.identifier.issn2068-0783
dc.identifier.scopus2-s2.0-85153474966en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage369en_US
dc.identifier.urihttps://doi.org/10.24264/icams-2022.III.19
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14149
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInst. Nat. Cercetare-Dezvoltare Text. Pielarieen_US
dc.relation.ispartofICAMS Proceedings of the International Conference on Advanced Materials and Systemsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC. albicansen_US
dc.subjectlozengeen_US
dc.subjectproliaxiaen_US
dc.subjectS. aureusen_US
dc.subjectS. pyogenesen_US
dc.subjectthroat infectionen_US
dc.titleEFFICACY OF CAPSAICIN ON CELL ADHESION AND INVASION OF ORAL PATHOGENSen_US
dc.typeConference Objecten_US

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