Apoptotic effects of artificial feed supplemented with Thymus vulgaris on Oncorhynchus mykiss against Yersinia ruckeri
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Dosyalar
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
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Yayıncı
Natl Inst Science Communication-Niscair
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Chemical composition of the essential oil was analyzed by GC-MS, and found to contain the phenol (40.95 %) as major component. Results showed that Y. ruckeri (3 x 10(7)cfit fish(-1)) infection caused the characteristic symptoms on rainbow trout (petechial hemorrhages on the surface of body and liver). Y. ruckeriinducedinhibitions of Cas-3, Cas-8, p53 and HSP-70. After the administration of thyme essential oil (10 mg kg(-1) diet) to infected fish tissues, Cas-3, Cas-8, p53 and HSP-70 mRNAs were up-regulated by 9.31, 9.18, 9.58, and 6,1 fold change, respectively. According to the results of the study, the inhibitions seen all analyzed genes were due to Y. ruckeri infection. However, they were entirely increased by thyme treatment. Thus, targeting proapoptotic proteases by agents such as T. vulgaris could improve therapeutic options for infectious disease in fish.
Açıklama
Anahtar Kelimeler
Apoptotic genes, Oncorhynchus myldss, Thymus vulgaris, Yersinia ruckeri
Kaynak
Indian Journal of Geo-Marine Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
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Cilt
46
Sayı
6
