Apoptotic effects of artificial feed supplemented with Thymus vulgaris on Oncorhynchus mykiss against Yersinia ruckeri

dc.authoridKucukgul, Azime/0000-0002-0515-6667
dc.contributor.authorKucukgul, Altug
dc.contributor.authorKucukgul, Azime
dc.date.accessioned2024-09-18T20:02:35Z
dc.date.available2024-09-18T20:02:35Z
dc.date.issued2017
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractChemical composition of the essential oil was analyzed by GC-MS, and found to contain the phenol (40.95 %) as major component. Results showed that Y. ruckeri (3 x 10(7)cfit fish(-1)) infection caused the characteristic symptoms on rainbow trout (petechial hemorrhages on the surface of body and liver). Y. ruckeriinducedinhibitions of Cas-3, Cas-8, p53 and HSP-70. After the administration of thyme essential oil (10 mg kg(-1) diet) to infected fish tissues, Cas-3, Cas-8, p53 and HSP-70 mRNAs were up-regulated by 9.31, 9.18, 9.58, and 6,1 fold change, respectively. According to the results of the study, the inhibitions seen all analyzed genes were due to Y. ruckeri infection. However, they were entirely increased by thyme treatment. Thus, targeting proapoptotic proteases by agents such as T. vulgaris could improve therapeutic options for infectious disease in fish.en_US
dc.identifier.endpage1174en_US
dc.identifier.issn0379-5136
dc.identifier.issn0975-1033
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85020117704en_US
dc.identifier.scopusquality#BAŞV!en_US
dc.identifier.startpage1170en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7880
dc.identifier.volume46en_US
dc.identifier.wosWOS:000406894600012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNatl Inst Science Communication-Niscairen_US
dc.relation.ispartofIndian Journal of Geo-Marine Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApoptotic genesen_US
dc.subjectOncorhynchus myldssen_US
dc.subjectThymus vulgarisen_US
dc.subjectYersinia ruckerien_US
dc.titleApoptotic effects of artificial feed supplemented with Thymus vulgaris on Oncorhynchus mykiss against Yersinia ruckerien_US
dc.typeArticleen_US

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