Could early septal involvement in the remodeling process be related to the advance hypertensive heart disease?
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Quantitative imaging analyses showed an earlier septal wall involvement in hypertension. We planned to determine the effect of hypertension on regionalmyocardial performance index (MPI) in a hypertensive patient population. Methods: We evaluated 119 hypertensive patients who were divided into gr. I:57 patients without left ventricular hypertrophy (LVH), (53.1 +/- 10 years), and gr.II:62 patients with LVH (55.1 +/- 9 years) using conventional and tissue doppler imaging. They were compared with gr. III, a sex-age-matched normal control group (37 subjects, 53.0 +/- 10 years). Results: We detected basal septal and basal lateral contraction time (CT), isovolumetric CT and relaxation time (IVRT) and MPI. EF was 68 +/- 5 % in gr. I, 69 +/- 5 % in gr. II, 69 +/- 4 % in gr. III. LV mass index was 122 +/- 11 g/m2 in gr. I, 148 +/- 13 g/m2 in gr. II and 118 +/- 13 g/m2 in gr. III. Concentric LVH was detected in gr. II (relative wall thickness=0.49 +/- 0.8). LV septal and lateral MPI were abnormal in both hypertensive groups (p < 0.0001). Septal MPI was correlated moderately with septal wall thickness (r = 0.447, p < 0.001). Conclusions: LV diastolic dysfunction becomes more severe in septal wall than lateral wall in hypertensive LVH. Septal myocardial performance is more dominantly affected by hypertension possibly due to earlier septal involvement in disease course. Septal MPI is correlated moderately with septal wall thickness. (C) 2015 Published by Elsevier Ireland Ltd.
Açıklama
Anahtar Kelimeler
Regional myocardial performance, Regional myocardial remodeling, Hypertensive heart disease
Kaynak
Ijc Heart & Vasculature
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
7
