Investigation of Shielding Parameters of Fast Neutrons for Some Chemotherapy Drugs by Different Calculation Methods
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Prof.Dr. İskender AKKURT
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, we investigated the neutron attenuation properties of twelve different chemotherapy drugs utilizing various computational techniques. The computed fast neutron effective removal cross-section (?R, cm-1) results were compared with empirical formulas, Monte Carlo simulation data obtained from MCNP, MRCsC, and Phy-X/PSD computer program results. Additionally, within each calculation method, the half-value layer (HVL) and the mean free path (?) values were determined. Our calculations revealed that, when compared to water and paraffin, Gemcitabine, Etoposide, Vincristine, and Doxorubicin exhibited the highest ?R values, while Oxaliplatin exhibited the lowest ?R value. Understanding and determining the radiation properties of drugs, especially in treatment methods involving radiation, will provide an advantage for both patients and clinical personnel. t © IJCESEN.
Açıklama
Anahtar Kelimeler
Chemotherapy drugs, MRCsC, Neutron shielding, Phy-X/PSD, Removal cross section
Kaynak
International Journal of Computational and Experimental Science and Engineering
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
9
Sayı
4
