Clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in dogs with infectious tracheobronchitis

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dc.contributor.authorHaydardedeoğlu, Ali Evren
dc.contributor.authorÇolakoğlu, Ekrem Çağatay
dc.contributor.authorAlihosseini, Hadi
dc.contributor.authorKaya, Ufuk
dc.date.accessioned2024-09-19T16:23:37Z
dc.date.available2024-09-19T16:23:37Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractCanine infectious tracheobronchitis (ITB) is a highly contagious disease of dogs expressed with remarkable respiratory signs. Therapy with antibiotics in canine ITB still remains questionable. The purpose of this study was to compare the clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in the treatment of canine ITB. Client-owned dogs with canine ITB signs (n=60) were enrolled in this prospective, controlled, and randomized blinded clinical trial. A computer-generated list randomization was employed to assign the dogs equally into the Group CLA: clarithromycin (25 mg/kg, PO), the Group AMX: amoxicillin and clavulanic acid (25 mg/kg, PO), the Group ENR: enrofloxacin (2.5 mg/kg, PO), and the Group DOX: doxycycline (5 mg/kg, PO). The administration of CLA alleviated the cough sign earlier than DOX. The recovery time of oculonasal discharge in group CLA were also earlier compared to the other groups. The tracheal sensitivity also disappeared earlier in the Groups CLA and AMX. In conclusion although there is no always statistically significance between groups, clarithromycin appears to be superior to other antibiotics suggesting that it can be the first antibiotic choice to alleviate the ITB signs in dogs.en_US
dc.identifier.doi10.31797/vetbio.1336336
dc.identifier.endpage215en_US
dc.identifier.issn2548-1150
dc.identifier.issue3en_US
dc.identifier.startpage210en_US
dc.identifier.trdizinid1216307en_US
dc.identifier.urihttps://doi.org/10.31797/vetbio.1336336
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1216307
dc.identifier.urihttps://hdl.handle.net/20.500.12483/16009
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of advances in vetbio science and techniquesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntibioticsen_US
dc.subjectdogen_US
dc.subjectinfectionen_US
dc.subjecttracheobronchitisen_US
dc.titleClinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in dogs with infectious tracheobronchitisen_US
dc.typeArticleen_US

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