Transrektal prostat biyopsisi sonrası akut bakteriyel prostatit sıklığı ve risk faktörleri
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Date
2013
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info:eu-repo/semantics/openAccess
Abstract
Amaç: Bu çalışmada amaç, transrektal prostat biyopsisi sonrası meydana gelen akut bakteriyel prostatit (ABP) sıklığını ve risk faktörlerini araştırmaktır. Yöntem: Mustafa Kemal Üniversitesi Tıp Fakültesi Hastanesi Üroloji Bölümü’nde Şubat 2010-Nisan 2012 tarihleri arasında ultrasononografi eşliğinde transrektal prostat biyopsi yapılan 335 hasta retrospektif olarak incelendi. Hastaların yaşı, özgeçmişindeki kronik hastalıklar, prostat hacmi, biyopsideki kor sayısı, biyopsi endikasyonları, kaçıncı kez biyopsi yapıldığı, ABP gelişenlerin idrar ve kan kültürü sonuçları kaydedildi. Bulgular: Biyopsi sonrası ABP sıklığı %2.4 olarak bulundu. ABP gelişen 8 olgunun 6’sında (%75) idrar ve/veya kan kültüründe levofloksasine dirençli Escherichia coli ürediği ve bunların 3’ünün (%50) geniş spektrumlu beta-laktamaz ürettiği belirlendi. İzolatlar sefalosporinlere ve aminoglikozitlere duyarlı olarak bulundu. ABP gelişen hastalarda anlamlı olarak daha yüksek oranda tekrar biyopsi yapıldığı belirlendi. Sonuç: Transrektal prostat biyopsisi profilaksisinde florokinolonlar birçok olguda etkin antibiyotiklerdir. Birden fazla biyopsi uygulaması ABP gelişimini arttırabilir. ABP gelişen olgularda florokinolonlara yüksek oranda direnç görülebileceğinden, sefalosporinler ve aminoglikozitlerle tedavi daha etkin olabilir.
Aim: It is aimed to investigate frequency and risk factors of acute bacterial prostatitis (ABP) after transrectal prostate biopsy. Method: Three hundred and thirty five patients, who underwent ultrasound-guided transrectal prostate biopsy at Urology Department of Mustafa Kemal University, Medicine School, between February 2010- April 2012, were retrospectively evaluated. Age, history of chronic diseases, prostate volume, number of core in biopsy, indications of biopsy, number of previous biopsies and results of urine and blood culture test in patients with ABP were recorded. Findings: Frequency of ABP was found as 2.4% after biopsy. It was found that there was levofloxacin- resistant Escherichia coli growth in urine and/or blood culture tests in 6 (75%) of the 8 cases in which ABP was developed after biopsy. It was detected that, of these, 3 (50%) produced broad spectrum beta- lactamases. Isolates were found to be susceptible to cephalosporins and aminoglycosides. It was found that number of repeated biopsies was significantly higher in patients with ABP. Conclusion: In many cases, fluoroquinolones are effective antibiotics in the prophylaxis of transrectal biopsy. Repeated biopsies may increase development of ABP. Cephalosporins and aminoglycosides may be more effective in the treatment, as higher rates of resistance to fluoroquinolones may be encountered in patients with ABP.
Aim: It is aimed to investigate frequency and risk factors of acute bacterial prostatitis (ABP) after transrectal prostate biopsy. Method: Three hundred and thirty five patients, who underwent ultrasound-guided transrectal prostate biopsy at Urology Department of Mustafa Kemal University, Medicine School, between February 2010- April 2012, were retrospectively evaluated. Age, history of chronic diseases, prostate volume, number of core in biopsy, indications of biopsy, number of previous biopsies and results of urine and blood culture test in patients with ABP were recorded. Findings: Frequency of ABP was found as 2.4% after biopsy. It was found that there was levofloxacin- resistant Escherichia coli growth in urine and/or blood culture tests in 6 (75%) of the 8 cases in which ABP was developed after biopsy. It was detected that, of these, 3 (50%) produced broad spectrum beta- lactamases. Isolates were found to be susceptible to cephalosporins and aminoglycosides. It was found that number of repeated biopsies was significantly higher in patients with ABP. Conclusion: In many cases, fluoroquinolones are effective antibiotics in the prophylaxis of transrectal biopsy. Repeated biopsies may increase development of ABP. Cephalosporins and aminoglycosides may be more effective in the treatment, as higher rates of resistance to fluoroquinolones may be encountered in patients with ABP.
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Van Tıp Dergisi
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Volume
20
Issue
2
