Evaluation of the Effect of Mortality, Life Expectancy, and Treatment Modalities of Sickle Cell Patients on Mortality

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dc.contributor.authorKaya, Mehmet Nur
dc.contributor.authorIlhan, Gul
dc.date.accessioned2024-09-18T20:27:54Z
dc.date.available2024-09-18T20:27:54Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: We aimed to contribute to the literature by investigating the causes of mortality, average life expectancies, and the clinical features that occur in this process, in relation to sickle cell disease (SCD), and by comparing the results obtained with other similar clinical studies. Materials and Methods: This study was designed as a monocentric, cross-sectional, and retrospective study. The patient files were reviewed in terms of the age, use of hydroxyurea, use of chelators, exchange transfusion history, surgical operation history, the annual frequency of painful crises, the annual hospitalization frequency, and the annual frequency of follow-up visits which the patients have attended, the complications experienced by the patients, and the causes of mortality. Results: Acute chest syndrome was the most prevalent cause of death of the patients included in our study. No significant difference was found between the premature death and late death groups, that is, the groups that we have determined on the basis of the SCD patients ages of death, in terms of use of hydroxyurea, use of iron chelator, and use of exchange transfusion depending on the disease. Conclusion: Based on our findings, acute chest syndrome was the primary cause of death in SCD patients we have studied, followed by pulmonary embolism. Use of hydroxyurea, use of iron chelator, exchange transfusion history, and surgical operation history due to SCD were not found to be significantly effective when the mean age of death reported in the literature was taken as the base value.en_US
dc.identifier.doi10.14744/etd.2020.06337
dc.identifier.endpage277en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue3en_US
dc.identifier.startpage273en_US
dc.identifier.trdizinid490492en_US
dc.identifier.urihttps://doi.org/10.14744/etd.2020.06337
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/490492
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10590
dc.identifier.volume43en_US
dc.identifier.wosWOS:000648828500012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherErciyes Univ Sch Medicineen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHydroxyureaen_US
dc.subjectmortalityen_US
dc.subjectsickle cell diseaseen_US
dc.titleEvaluation of the Effect of Mortality, Life Expectancy, and Treatment Modalities of Sickle Cell Patients on Mortalityen_US
dc.typeArticleen_US

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