The effect of lavandula essential oils on release of niflumic acid from collagen hydrolysates

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dc.authoridPOPA, lacramioara.popa@umfcd.ro/0000-0002-5125-7960
dc.authoridCiprian, Chelaru/0000-0003-1369-3742
dc.authoridRusu, Laura-Cristina/0000-0001-6375-4705
dc.authoridNitipir, Cornelia/0000-0002-5985-3759
dc.authoridPOPA, LACRAMIOARA/0000-0002-3139-9865
dc.authoridKaya, Durmus Alpaslan/0000-0003-3544-9214
dc.authoridGHICA, Mihaela Violeta/0000-0001-6853-9203
dc.contributor.authorGhica, Mihaela Violeta
dc.contributor.authorAlbu, Madalina Georgiana
dc.contributor.authorKaya, Durmus Alpaslan
dc.contributor.authorPopa, Lacramioara
dc.contributor.authorOzturk, Sevket
dc.contributor.authorRusu, Laura-Cristina
dc.contributor.authorDinu-Pirvu, Cristina
dc.date.accessioned2024-09-18T20:11:34Z
dc.date.available2024-09-18T20:11:34Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of this paper is to design and characterize some drug delivery systems (DDS) based on collagen hydrolysates (H), niflumic acid as a non-steroidal anti-inflammatory model drug and two essential oils of Lavandula officinalis L. (LO) and Lavandula stoechas L. subsp. Stoechas (LS), for use in healing cutaneous wounds with post-lesion inflammatory response. The essential oils are characterized by GC-MS. The wettability capacity of collagen hydrolysate powders was assessed by contact angle measurement. Niflumic acid release was investigated using a modified Franz diffusion cell, and the diffusion coefficient, time-lag and drug flux were determined. The kinetic parameters were found to be influenced by different concentrations and types of essential oils. These therapeutical products, based on collagen hydrolysates and synergistic drug associations, could have potential biomedical application in wound healing treatment.en_US
dc.description.sponsorshipSectoral Operational Programme Human Resources Development of the Ministry of European Funds [POSDRU/159/1.5/S/132395, PIII-C2-PCFI]en_US
dc.description.sponsorshipThe work has been funded by the Sectoral Operational Programme Human Resources Development 2007-2013 of the Ministry of European Funds through the Financial Agreement POSDRU/159/1.5/S/132395 and project no PIII-C2-PCFI (2015-2016) DENTALOCT.en_US
dc.identifier.doi10.1007/s11814-015-0284-7
dc.identifier.endpage1330en_US
dc.identifier.issn0256-1115
dc.identifier.issn1975-7220
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84959156107en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1325en_US
dc.identifier.urihttps://doi.org/10.1007/s11814-015-0284-7
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8955
dc.identifier.volume33en_US
dc.identifier.wosWOS:000374266300024en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKorean Institute Chemical Engineersen_US
dc.relation.ispartofKorean Journal of Chemical Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCollagen Hydrolysateen_US
dc.subjectNiflumic Aciden_US
dc.subjectLavandula Essential Oilsen_US
dc.subjectRelease Kineticsen_US
dc.titleThe effect of lavandula essential oils on release of niflumic acid from collagen hydrolysatesen_US
dc.typeArticleen_US

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