Türkiye’nin Güneydoğusunda çocukluk çağı brusellozu : retrospektif analiz
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Tarih
2013
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada dört yıllık süreçte brusellozis tanısıyla yatırılarak takip ve teda- vi edilen hastaların demografik ve klinik özelliklerinin değerlendirilmesi amaçlandı. Yöntemler: Retrospektif olarak yapılan bu çalışmaya 2003-2007 yılları arasında Dicle Üniversitesi Çocuk İnfeksiyon Hastalıkları Servisine brusellozis tanısı ile yatırılan 34 olgu alındı. Hastaların demografik özellikleri, klinik yakınmaları, fizik muayene ve laboratuvar bulguları değerlendirildi. Standart tüp aglütinasyon testi, Rose Bengal testi ve klinik bulgular tanı kriteri olarak kullanıldı. Bulgular: Hastaların 12 (%35)’si kız, 22 (%65)’si erkekti. Hastaların ortalama yaşı 9,2±3,4 yıl idi. 21 (%61,7) hasta kırsal alandan başvurmuştu. İki hasta dışında tüm hastalar, çiğ süt ve süt ürünleri tüketmişti. Hastaların yakınma ve bulguların arasın- da ateş (30, %88,2) ve kas-iskelet sistem yakınmaları (26, %76,4) ön plandaydı. Laboratuvar incelemelerinde hematolojik tutulum belirgindi. Tedavide sekiz yaşın- dan küçük çocuklara trimetoprim-sulfametoksazol+rifampisin, sekiz yaşından büyük- lere doksisiklin+rifampisin 6 hafta boyunca uygulandı. Dört hastada relaps görüldü. Sonuç: Brusellozisin başvuru nedenleri arasında kas iskelet sistem yakınmaları ve ateş ilk sıradadır. Hematolojik sistem bulguları olan hastada brusellozis ayırıcı tanı- lar arasında olmalıdır. Tedavinin başarılı olması ve relaps oluşmaması için kombine tedaviler yeterli süre verilmelidir.
Objective: To evaluate the clinical and laboratory findings, treatment modalities and outcomes of children with brucellosis in a four-year period Methods: This retrospective study included 34 children who were admitted to Dicle University Pediatric Infectious Diseases Service with brucellosis between 2003-2007. Demographic features, clinical symptoms, physical examination and laboratory fin- dings of patients were evaluated. The standard tube agglutination test, Rose Bengal test and clinical findings were used as diagnostic criteria for brucellosis. Results: In the study, twelve patients (35%) were female and 22 (65%) were male. The mean age was 9.2±3.4 years. Twenty-one patients (61.7%) were from rural areas of Turkey. All of the children except two patients have reported to consume unprocessed milk and dairy products. The most frequent complaints and clinical findings were fever (88.2%) and musculo-skeletal system symptoms (76.4%). Hematological invol- vement was significantly apparent in laboratory results. Trimethoprim- sulfamethoxazole+rifampicin were administered to children smaller than 8 years and doxycycline+rifampicin to children older than 8 years during 6 weeks for treatment. Four patients were relapsed. Conclusion: Musculoskeletal system complaints and fever are the most common symptoms in brucellosis. Brucellosis should be considered in the differential diagnosis of patients with hematological signs. Combined treatments should be administered within a sufficient period to provide successful treatment and prevent relapse.
Objective: To evaluate the clinical and laboratory findings, treatment modalities and outcomes of children with brucellosis in a four-year period Methods: This retrospective study included 34 children who were admitted to Dicle University Pediatric Infectious Diseases Service with brucellosis between 2003-2007. Demographic features, clinical symptoms, physical examination and laboratory fin- dings of patients were evaluated. The standard tube agglutination test, Rose Bengal test and clinical findings were used as diagnostic criteria for brucellosis. Results: In the study, twelve patients (35%) were female and 22 (65%) were male. The mean age was 9.2±3.4 years. Twenty-one patients (61.7%) were from rural areas of Turkey. All of the children except two patients have reported to consume unprocessed milk and dairy products. The most frequent complaints and clinical findings were fever (88.2%) and musculo-skeletal system symptoms (76.4%). Hematological invol- vement was significantly apparent in laboratory results. Trimethoprim- sulfamethoxazole+rifampicin were administered to children smaller than 8 years and doxycycline+rifampicin to children older than 8 years during 6 weeks for treatment. Four patients were relapsed. Conclusion: Musculoskeletal system complaints and fever are the most common symptoms in brucellosis. Brucellosis should be considered in the differential diagnosis of patients with hematological signs. Combined treatments should be administered within a sufficient period to provide successful treatment and prevent relapse.
Açıklama
Anahtar Kelimeler
Pediatri
Kaynak
İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
1
