Cutaneous involvement in multiple myeloma : a case report
Yükleniyor...
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Multipl myelom (MM) kemik iliğinden köken alan ve m onoklonal immunglobulin üreten plazma hücreleri ile kara kterize hematolojik bir malinignitedir. MM’li hastalarda deri tutulumu çok nadir görülmektedir. Yetmiş üç yaşında, IgG lambda MM tanısı olan hasta deri lezyonları nedeniyle Dahiliye bölümü tarafından bölümümüze konsülte edildi. Yapılan dermatolojik muayenede üst ekstremitelerde, gövde ön ve arka yüzd e dağınık yerleşimli, çapları 2 -5 cm arasında değişen, eritemli viyolase renkte toplam 10 adet tümöral lezyon izlendi. Lezyonlardan alınan biyopsinin histopatolojik incelemesinde lambda monoklonaliteli diffüz atipik plazma hücre infiltrasyonu saptanması ne d eniyle hastanın lezyonları MM deri tutulumu olarak değe rlendirildi.
Multiple myeloma (MM) is a hematological malignity that originates from the bone marrow and is characterized by plasma cells that produce monoclonal immunoglobulin. Cutaneous involvement is very rare in patients with MM. A 73 -year-old, male patient, who has a diagnosis of IgG lam bda MM, was referred to our clinic from the Department of Internal Medicine due to his skin lesions. The dermatolog ical examination revealed a total of 10 erythematous viol aceous-tumoral lesions with a diameter varying between 2 -5 cm, on upper extremities, the front and back of the body. The lesions of the patient were considered as cutaneous involvement of MM because histopathological examination of ski n biopsy is showed diffuse atypical plasma cell infiltration with lambda monoclonality.
Multiple myeloma (MM) is a hematological malignity that originates from the bone marrow and is characterized by plasma cells that produce monoclonal immunoglobulin. Cutaneous involvement is very rare in patients with MM. A 73 -year-old, male patient, who has a diagnosis of IgG lam bda MM, was referred to our clinic from the Department of Internal Medicine due to his skin lesions. The dermatolog ical examination revealed a total of 10 erythematous viol aceous-tumoral lesions with a diameter varying between 2 -5 cm, on upper extremities, the front and back of the body. The lesions of the patient were considered as cutaneous involvement of MM because histopathological examination of ski n biopsy is showed diffuse atypical plasma cell infiltration with lambda monoclonality.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Abant Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
3
