The Complete Success in Refractory Mooren's Ulcer Treated with Infliximab
Yükleniyor...
Dosyalar
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose To describe the management and outcome of two extremely rare and painful cases of Mooren's ulcer, an idiopathic peripheral autoimmune-associated ulcerative corneal disease. Methods Case report with literature review on the management of ocular inflammation in Mooren's ulcer. Results A 47-year-old female and a 76-year-old female presented with progressive bilateral Mooren's ulcer that were refractory to conventional immunosuppressive therapy. Following treatment with infliximab, an anti-tumor necrosis factor alpha, a significant improvement in disease progression was observed, with no corneal thinning or perforation at follow-ups. Conclusion This case report highlights how infliximab can be effective in cases with Mooren's ulcer refractory to conventional therapies.
Açıklama
Anahtar Kelimeler
Anti-tumor necrosis factor alpha, immunosuppresion, infliximab, Mooren's ulcer, peripheral ulcerative keratitits
Kaynak
Ocular Immunology and Inflammation
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
31
Sayı
4
