The Complete Success in Refractory Mooren's Ulcer Treated with Infliximab

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dc.authoridcakmak, ayse idil/0000-0003-4377-7314
dc.authoridYildirim, Nilgun/0000-0001-6266-4951
dc.contributor.authorCakmak, Ayse Idil
dc.contributor.authorAkova, Yonca
dc.contributor.authorYildirim, Nilgun
dc.date.accessioned2024-09-18T20:02:32Z
dc.date.available2024-09-18T20:02:32Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose To describe the management and outcome of two extremely rare and painful cases of Mooren's ulcer, an idiopathic peripheral autoimmune-associated ulcerative corneal disease. Methods Case report with literature review on the management of ocular inflammation in Mooren's ulcer. Results A 47-year-old female and a 76-year-old female presented with progressive bilateral Mooren's ulcer that were refractory to conventional immunosuppressive therapy. Following treatment with infliximab, an anti-tumor necrosis factor alpha, a significant improvement in disease progression was observed, with no corneal thinning or perforation at follow-ups. Conclusion This case report highlights how infliximab can be effective in cases with Mooren's ulcer refractory to conventional therapies.en_US
dc.identifier.doi10.1080/09273948.2022.2091615
dc.identifier.endpage688en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue4en_US
dc.identifier.pmid35830240en_US
dc.identifier.scopus2-s2.0-85134032514en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage682en_US
dc.identifier.urihttps://doi.org/10.1080/09273948.2022.2091615
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7841
dc.identifier.volume31en_US
dc.identifier.wosWOS:000824358100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology and Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnti-tumor necrosis factor alphaen_US
dc.subjectimmunosuppresionen_US
dc.subjectinfliximaben_US
dc.subjectMooren's ulceren_US
dc.subjectperipheral ulcerative keratititsen_US
dc.titleThe Complete Success in Refractory Mooren's Ulcer Treated with Infliximaben_US
dc.typeArticleen_US

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