İnfektif endokarditin klinik sonuçları üzerine hematolojik ve biyokimyasal parametrelerin etkisi
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Tarih
2011
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info:eu-repo/semantics/openAccess
Özet
Amaç: Çalışmamızda İnfektif endokarditli (İE) hastalarda hematolojik parametrelerdeki değişiklikleri ve bu değişikliklerin komplikasyon ve mortalite oranları ile ilişkisini araştırmayı amaçladık. Gereç ve yöntem: Dicle Üniversitesi, Atatürk Üniversitesi ve Harran Üniversitesi Tıp Fakültelerinin kardiyoloji bölümlerinde İE tanısı ile Haziran 2007 den Haziran 2011 tarihleri arasında yatırılan 44 hasta retrospektif olarak değerlendirildi. İE tanısında Duke kriterleri esas alındı. Hematolojik ve biyokimyasal parametreler kaydedildi. Bulgular: Yaşayan hastalar ile karşılaştırıldığında, İE bağlı ölen hastalarda ortalama yaş, beyaz küre sayısı, nötrofil sayısı, ortalama trombosit hacmi ve komplikasyon oranı daha yüksek bulundu (sırasıyla, p <0.004, p <0.05, p <0.03, p <0.05, p <0.01, p <0.004). Ancak trombosit sayısı daha düşüktü (p <0.05). Bununla birlikte komplikasyon gelişen hastalar ile komplikasyon gelişmeyen hastalar karşılaştırıldığında laboratuar bulguları açısından gruplar arasında fark yoktu (p>0.05). Sonuç: İnfektif endokarditde yaş, ortalama trombosit hacmi ve komplikasyon varlığı mortalite için risk faktörleri olarak kullanılabilir. Ayrıca kan kültüründe S.aureus üremesi yüksek komplikasyon oranları ile ilişkilidir.
Objectives: This study was designed to examine haematological changes in infective endocarditis (IE) and the association between laboratory findings and mortality or complications including events in IE. Materials and methods: Forty-four patients who were hospitalized with a diagnosis of IE at the Department of Cardiology, Dicle University, Ataturk University and Harran University, from June 2007 to June 2011, were retrospectively evaluated. The diagnosis of IE was made clinically and was confi rmed with Duke&#8217;s criteria. The haematological and biochemical parameters were recorded. Results: Age, white blood cell count, neutrophil count, neutrophil lymphocyte ratio, mean platelet volume and complication rate (p <0.004, p <0.05, p <0.03, p <0.05, p <0.01, p <0.004, respectively) were elevated in patients who died due to infective endocarditis compared with patients who survived. However, platelet count were lower in patients died (p <0.05). Additionally, patients who developed complications were no difference laboratory findings compared with patients without complications. Conclusion: Age, MPV and presence of complications can be used as risk factors for mortality in IE. In addition, S.aureus is associated with complications.
Objectives: This study was designed to examine haematological changes in infective endocarditis (IE) and the association between laboratory findings and mortality or complications including events in IE. Materials and methods: Forty-four patients who were hospitalized with a diagnosis of IE at the Department of Cardiology, Dicle University, Ataturk University and Harran University, from June 2007 to June 2011, were retrospectively evaluated. The diagnosis of IE was made clinically and was confi rmed with Duke&#8217;s criteria. The haematological and biochemical parameters were recorded. Results: Age, white blood cell count, neutrophil count, neutrophil lymphocyte ratio, mean platelet volume and complication rate (p <0.004, p <0.05, p <0.03, p <0.05, p <0.01, p <0.004, respectively) were elevated in patients who died due to infective endocarditis compared with patients who survived. However, platelet count were lower in patients died (p <0.05). Additionally, patients who developed complications were no difference laboratory findings compared with patients without complications. Conclusion: Age, MPV and presence of complications can be used as risk factors for mortality in IE. In addition, S.aureus is associated with complications.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Dicle Tıp Dergisi
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Cilt
38
Sayı
4
