Pneumonic varicella in patient with inactive hepatitis B : A case report
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Tarih
2012
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Nadir rastlanılmasına rağmen varicella zoster virus (VZV) ilişkili pnömoni, virüsün sıklıkla yetişkinleri etkileyen en ciddi komplikasyonudur ve yüksek mortaliteyle seyreder. Bu çalışmada Hepatit B virüs taşıyıcısı 29 yaşında bir erkek hastada VZV pnömonisi tanımlanmaktadır. Hasta beş gündür devam eden halsizlik, boğaz ağrısı, ateş, öksürük ve hafif dispne şikayetleri ile başvurdu. Ayrıca ekzantematöz veziküler döküntüleri vardı. Döküntüler saçlı deriyi de kapsayacak şekilde tüm vücuda yayılmıştı. Fakat hastanın ateşi yoktu ve vital bulgular normaldi. Deri muayenesi ile tüm vücutta papüloveziküllü yaygın polimorfik döküntü ve kabuklu lezyonlar görüldü. Serolojik bulgular, VZV IgM pozitif, VZV IgG pozitif ve HBsAg pozitif idi. Göğüs radyografisinde bilateral pnömonik infiltrasyonlar görüldü. Hastaya valasiklovir ve klaritromisin verildi. Deri lezyonları on gün sonra kayboldu ve hasta tam olarak iyileşti. Sonuç olarak yetişkin hastalarda nadiren oluşan VZV pnömonisinin erken tanısı ve antivirallerle etkin tedavisi ciddi komplikasyonların gelişmesini önleyebilir.
Although rarely observed, varicella zoster virus (VZV)-related pneumonia is the most serious complication of the virus, which commonly affects adults and causes high mortality rates. In this study, we describe a case of VZV pneumonia in a 29-year-old male who is an inactive Hepatitis B virus carrier. The patient presented with a 5-day history of fatigue, sore throat, fever, cough and mild dyspnea. He also had an exanthematous vesicular rash. The rash had spread all over his body surface including the hairy skin. But he was not febrile and vital signs were normal. The skin examination exhibited a diffuse polymorphic rash with papules/vesicles, pustules and crusty lesions over the whole body. Serological findings were as follows: VZV IgM positive, VZV IgG positive and HBsAg positive. His chest X-ray showed bilateral pneumonic infiltrations. The patient was prescribed valacyclovir and clarithromycin. The skin lesions disappeared after ten days and the patient made a full recovery. We conclude that an early diagnosis of VZV pneumonia, which rarely occurs in adult patients and its effective treatment with antivirals may prevent the development of serious complications.
Although rarely observed, varicella zoster virus (VZV)-related pneumonia is the most serious complication of the virus, which commonly affects adults and causes high mortality rates. In this study, we describe a case of VZV pneumonia in a 29-year-old male who is an inactive Hepatitis B virus carrier. The patient presented with a 5-day history of fatigue, sore throat, fever, cough and mild dyspnea. He also had an exanthematous vesicular rash. The rash had spread all over his body surface including the hairy skin. But he was not febrile and vital signs were normal. The skin examination exhibited a diffuse polymorphic rash with papules/vesicles, pustules and crusty lesions over the whole body. Serological findings were as follows: VZV IgM positive, VZV IgG positive and HBsAg positive. His chest X-ray showed bilateral pneumonic infiltrations. The patient was prescribed valacyclovir and clarithromycin. The skin lesions disappeared after ten days and the patient made a full recovery. We conclude that an early diagnosis of VZV pneumonia, which rarely occurs in adult patients and its effective treatment with antivirals may prevent the development of serious complications.
Açıklama
Anahtar Kelimeler
Mikrobiyoloji, Enfeksiyon Hastalıkları
Kaynak
Journal of Microbiology and Infectious Diseases
WoS Q Değeri
Scopus Q Değeri
Cilt
2
Sayı
2
