Preeklampsı̇ olgularının hemogram sonuçlarındakı̇ ı̇nflamasyon belı̇rteçlerı̇nı̇n (nötrofı̇l
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Tarih
2021
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Hatay Mustafa Kemal Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Çalışmamızda gebeliğinde preeklampsi tanısı alan hastaların hemogram sonuçlarında inflamasyon markerlarından nötrofil/lenfosit oranı (NLR), platelet/lenfosit oranı (PLR) ve monosit/lenfosit oranı (MLR) nın değerlendirilmesi ve hafif-ağır preeklampsi gelişme ihtimali olan gebeleri, normal gebelerle karşılaştırarak hafif-ağır preeklampsiyi öngörebilmedeki yerinin belirlenmesi amaçlanmıştır. Yöntem: 148 ağır preeklampsi, 160 hafif preeklampsi olmak üzere toplam 308 preeklampsi ve 308 sağlıklı normotansif gebe olgusunun demografik verileri ve laboratuar testleri retrospektif olarak incelendi. Gruplar NLR, PLR ve MLR açısından incelendi. Bulgular: Gruplar arasında yaş bakımından fark bulunmadı. Preeklampsi grubunda parite, gestasyonel yaş, doğum kilosu ve APGAR skorları kontrol grubuna kıyasla düşüktü (p<0,001). NLR preeklampsi grubunda kontrol grubuna kıyasla istatistiksel anlamlı derecede yüksek bulundu (p<0,001). PLR' de anlamlı derecede düşük olarak bulundu (p<0,001). MLR de gruplar arasında anlamlı fark saptanmadı. Sonuç: NLR ve PLR preeklampsi varlığının gösterilmesinde bir parametre olarak kullanılabilir. MLR için istatistiksel anlamlı sonuç saptanmadı. Anahtar Kelime: gebelik, preeklampsi, nötrofil, lenfosit, monosit, inflamasyon
Objective: In our study, we evaluated the neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR) and monocyte / lymphocyte ratio (MLR) among the inflammation markers in the hemogram results of patients diagnosed with preeclampsia in pregnancy, and compared the pregnant women with the possibility of developing mild-severe preeclampsia It is aimed to determine its place in predicting mild-severe preeclampsia. Method: The demographic data and laboratory tests of 308 preeclampsia and 308 healthy normotensive pregnant cases, 148 severe preeclampsia, 160 mild preeclampsia, were evaluated retrospectively. Groups were examined in terms of NLR, PLR and MLR. Results: There was no difference for age between the groups. In the preeclampsia group, parity, gestational age, birth weight and APGAR scores were lower than the control group (p<0.001). The NLR was found to be significantly higher (p<0.001) and PLR was significantly lower in the preeclampsia group compared to the control group (p<0.001). There was no significant difference between the groups in MLR. Conclusion: NLR and PLR can be used as a parameter to show the presence of preeclampsia. There was no statistically significant result for MLR.
Objective: In our study, we evaluated the neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR) and monocyte / lymphocyte ratio (MLR) among the inflammation markers in the hemogram results of patients diagnosed with preeclampsia in pregnancy, and compared the pregnant women with the possibility of developing mild-severe preeclampsia It is aimed to determine its place in predicting mild-severe preeclampsia. Method: The demographic data and laboratory tests of 308 preeclampsia and 308 healthy normotensive pregnant cases, 148 severe preeclampsia, 160 mild preeclampsia, were evaluated retrospectively. Groups were examined in terms of NLR, PLR and MLR. Results: There was no difference for age between the groups. In the preeclampsia group, parity, gestational age, birth weight and APGAR scores were lower than the control group (p<0.001). The NLR was found to be significantly higher (p<0.001) and PLR was significantly lower in the preeclampsia group compared to the control group (p<0.001). There was no significant difference between the groups in MLR. Conclusion: NLR and PLR can be used as a parameter to show the presence of preeclampsia. There was no statistically significant result for MLR.
Açıklama
Anahtar Kelimeler
Kadın Hastalıkları ve Doğum, Obstetrics and Gynecology, pregnancy, preeklampsia, neutropfil, lymphocyte, monocytes, inflamation
