Anal sac carcinoma in a dog
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Tarih
2005
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu olguda 12 yaşlı, dişi, melez bir köpeğin anüsünün ventro-lateralinden sol arka bacak derisi altına doğru yayılan anal kese adenokarsinomunun klinik ve patomorfolojik bulguları açıklandı. Tümör, 20x15x10 cm boyutlarında, 1110 gr ağırlığında, nodüler bir yapıdaydı. Kesit yüzünde, kistik yapılar vardı. Mikroskobik olarak tümör; solid alanlar halinde dizilim gösteren, oval ya da yuvarlak şekilli, hiperkromatik çekirdekli, eozinofılik sitoplazmalı neoplastik hücrelerden ibaretti. Bazı alanlarda rozet formasyonları dikkati çekti. İmmunoperoksidaz yöntemiyle incelemede PCNA pozitif hücreler saptandı.
In this report, anal cell carcinoma located from ventro-laterally of anus, spreading out to subcutis of hind left leg was described with clinical and pathomorphological findings in a 12-year-old female mongrel-dog. The mass was of 20x15x10 cm in diameter, 1110 g in weight and it was showing nodular structure. Cut section of the mass was cystic. Microscopically; oval or round shaped neoplastic cells with hyperchromatic nuclei and eosinophilic cytoplasm had formed solid sheets. In some areas, the cells surrounded a small amount of eosinophilic secr.etion and constituted rosette formations. PCNA positive neoplastic cells were seen by immunoperoxidase method.
In this report, anal cell carcinoma located from ventro-laterally of anus, spreading out to subcutis of hind left leg was described with clinical and pathomorphological findings in a 12-year-old female mongrel-dog. The mass was of 20x15x10 cm in diameter, 1110 g in weight and it was showing nodular structure. Cut section of the mass was cystic. Microscopically; oval or round shaped neoplastic cells with hyperchromatic nuclei and eosinophilic cytoplasm had formed solid sheets. In some areas, the cells surrounded a small amount of eosinophilic secr.etion and constituted rosette formations. PCNA positive neoplastic cells were seen by immunoperoxidase method.
Açıklama
Anahtar Kelimeler
Veterinerlik
Kaynak
Ankara Üniversitesi Veteriner Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
52
Sayı
3