Is the risk of isolated coronary artery bypass graft surgery in women aged above 75 years higher compared to men ?
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Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada izole koroner arter baypas greft (KABG) cerrahisi yapılan 75 yaş üzeri kadın ve erkek hastalardaki muhtemel farklılıklar araştırıldı ve risk faktörleri belirlendi.Çalışmaplanı:Ocak 2004 - Ocak 2012 tarihleri arasında kardiyopulmoner baypas ile izole koroner baypas greft (KABG) cerrahisi uygulanmış olan toplam 174 hasta (121 erkek, 53 kadın; ort. yaş 77.1 yıl; dağılım 75-97 yıl) retrospektif olarak incelendi. Hastalar cinsiyetlerine göre iki gruba ayrıldı: Grup 1 erkek hastalardan, grup 2 ise kadın hastalardan oluşuyordu. Her iki grubun ameliyat öncesi risk faktörleri, ameliyat sırası ve sonrası verileri ve erken dönem mortalite oranları karşılaştırıldı.Bul gu lar: Diyabetes mellitus insidansı ve EuroSCORE değerleri kadınlarda daha yüksek iken, sigara içme oranı erkeklerde daha yüksek idi (sırasıyla p=0.012; p<0.01; p<0.01). Hasta başına düşen greft sayısı ve mediastinal drenaj hacmi erkeklerde daha yüksek iken, yoğun bakımda kalış süresi kadınlarda daha uzundu (sırasıyla, p=0.039; p=0.041; p<0.01). Sol internal mammaryan arter greft kullanımı, inotropik ilaç gereksinimi, intraaortik balon pompası desteği, nörolojik komplikasyonlar, atriyal fibrilasyon insidansı ve hastanede kalış süresi iki grupta da benzerdi. Grupların mortalite oranları arasında anlamlı bir fark bulunmadı [grup 1, 1.7% (n=2); grup 2, 3.8% (n=2)].So nuç: Yetmiş beş yaş üzeri kadın hastalarda, aynı yaş grubu erkeklere kıyasla, diyabetes mellitus insidansı, EuroSCORE değeri ve yoğun bakım ünitesinde kalış süresi daha yüksek olmasına rağmen, KABG cerrahisi benzer mortalite oranları ile yapılabilmektedir.
Background: This study aims to investigate the possible differences of male and female patients aged above 75 years undergoing isolated coronary artery bypass graft surgery (CABG) and to define the risk factors. Methods: Between January 2004 and January 2012, a total of 174 isolated on-pump CABG patients (121 males, 53 females; mean age 77.1 years; range 75 to 97 years) using cardiopulmonary bypass were retrospectively analyzed. The patients were divided into two groups according to their sex: Group 1 consisted of male patients, while group 2 consisted of female patients. Preoperative risk factors, intraoperative and postoperative data and early mortality rates of both groups were compared. Results: The incidence of diabetes mellitus and EuroSCORE values were higher in females, while smoking rates were higher in males (p=0.012; p<0.01; p<0.01, respectively). The number of graft per patient and mediastinal drainage volume were higher in males, whereas the length of intensive care unit stay was longer in females (p=0.039; p=0.041; p<0.01, respectively). The left internal mammary artery graft utilization, need for inotropic support, intra-aortic balloon pump support, neurological complications, the incidence of atrial fibrillation and length of hospital stay were similar in both groups. There was no significant difference in the mortality rates between the groups [group 1, 1.7% (n=2); group 2, 3.8% (n=2)]. Conclusion: Although women aged above 75 years may have a higher incidence of diabetes mellitus, EuroSCORE values and length of intensive care unit stay compared to age-matched men, CABG operations can be done with similar mortality rates.
Background: This study aims to investigate the possible differences of male and female patients aged above 75 years undergoing isolated coronary artery bypass graft surgery (CABG) and to define the risk factors. Methods: Between January 2004 and January 2012, a total of 174 isolated on-pump CABG patients (121 males, 53 females; mean age 77.1 years; range 75 to 97 years) using cardiopulmonary bypass were retrospectively analyzed. The patients were divided into two groups according to their sex: Group 1 consisted of male patients, while group 2 consisted of female patients. Preoperative risk factors, intraoperative and postoperative data and early mortality rates of both groups were compared. Results: The incidence of diabetes mellitus and EuroSCORE values were higher in females, while smoking rates were higher in males (p=0.012; p<0.01; p<0.01, respectively). The number of graft per patient and mediastinal drainage volume were higher in males, whereas the length of intensive care unit stay was longer in females (p=0.039; p=0.041; p<0.01, respectively). The left internal mammary artery graft utilization, need for inotropic support, intra-aortic balloon pump support, neurological complications, the incidence of atrial fibrillation and length of hospital stay were similar in both groups. There was no significant difference in the mortality rates between the groups [group 1, 1.7% (n=2); group 2, 3.8% (n=2)]. Conclusion: Although women aged above 75 years may have a higher incidence of diabetes mellitus, EuroSCORE values and length of intensive care unit stay compared to age-matched men, CABG operations can be done with similar mortality rates.
Açıklama
Anahtar Kelimeler
Cerrahi, Kalp ve Kalp Damar Sistemi
Kaynak
Türk Göğüs Kalp Damar Cerrahisi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
22
Sayı
2
