Is Isolated Autoantibody Seropositivity a Risk Factor in the Development of Diabetic Nephropathy in Type 1 Diabetic Children?

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dc.contributor.authorTaktak, Aysel
dc.contributor.authorKara, Mehtap Akbalik
dc.contributor.authorCicek, Neslihan
dc.contributor.authorAlparslan, Caner
dc.contributor.authorUnal, Edip
dc.contributor.authorAgin, Mehmet
dc.contributor.authorOzbek, Mehmet Nuri
dc.date.accessioned2024-09-18T20:02:46Z
dc.date.available2024-09-18T20:02:46Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: Diabetic nephropathy is one of the most important complications in diabetes mellitus. We aimed to examine the influence of organ-specific antibody seropositivity in diabetic nephropathy. Methods: Patients with type 1 diabetes and no evidence of celiac disease, thyroid dysfunction, and other kidney diseases and with an annual average HbA1c level <10%, body mass index <25 kg/m(2), and normal blood pressure were enrolled. Results: Eighty patients (39 boys and 41 girls) were evaluated. Twenty patients with moderately increased albuminuria (diabetic nephropathy group) and 60 patients without albuminuria (control group) showed no statistical difference in age, gender, diabetes duration, age at diagnosis, kidney function tests, and mean blood pressure measurements. Compared to control group, the mean anti-thyroglobulin level and anti-thyroxin peroxidase level were statistically higher in the diabetic nephropathy group, P =.004 and P =.045, respectively. However, the thyroid function tests were normal in either group. Conclusion: Determination of the impact of autoantibody seropositivity on the risk of diabetic nephropathy in type 1 diabetic children could be a non-traditional marker in the risk assessment of diabetic nephropathy.en_US
dc.identifier.doi10.5152/turkjnephrol.2023.2289378
dc.identifier.endpage254en_US
dc.identifier.issn2667-4440
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85166949362en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage249en_US
dc.identifier.trdizinid1188763en_US
dc.identifier.urihttps://doi.org/10.5152/turkjnephrol.2023.2289378
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1188763
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8019
dc.identifier.volume32en_US
dc.identifier.wosWOS:001034452400012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Journal of Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmune diseasesen_US
dc.subjectchildrenen_US
dc.subjectnephropathyen_US
dc.subjectType 1 diabetes mellitusen_US
dc.titleIs Isolated Autoantibody Seropositivity a Risk Factor in the Development of Diabetic Nephropathy in Type 1 Diabetic Children?en_US
dc.typeArticleen_US

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