Mustafa Kemal üniversitesi tıp fakültesi yoğun bakım ünitesi’nde 2011 yılında sağlık hizmeti ile ilişkili infeksiyonların değerlendirilmesi
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2012
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info:eu-repo/semantics/openAccess
Özet
Bu çalışmada, hastanemiz yoğun bakım ünitesinde 2011 yılında gelişen sağlık hizmeti ile ilişkili infeksiyonların değerlendirilmesi amaçlanmıştır. Yoğun bakım ünitesinde hastaya dayalı, aktif, prospektif sürveyans yapılmıştır. Hastane infeksiyonu tanısında Hastalık Kontrol ve Önleme Merkezi (CDC) tanı kriterleri kullanılmıştır. İzole edilen infeksiyon etkenleri konvansiyonel yöntemler ve VİTEK2 Compact (bioMérieux, Fransa) otomatize sistemle tanımlanmıştır. Antibiyotik duyarlılık testleri Klinik ve Laboratuvar Standartları Enstitüsü (CLSI) kriterlerine göre disk difüzyon yöntemi ile yapılmıştır. Çalışma boyunca yoğun bakım ünitesinde 415 hasta 3654 hasta günü izlenmiştir. Bu sürede 70 hastane infeksiyonu tanımlanmış, hastane infeksiyonu hızı % 16.9; hastane infeksiyonu insidans dansitesi binde 19.2 olarak hesaplanmıştır. Hastane infeksiyonu tanısı alan hastalardan 71 mikroorganizma izole edilmiş, bunların 36’sını Gram negatif bakteriler, 17’sini Gram pozitif bakteriler ve 18’ini kandida türleri oluşturmuştur. Tüm sağlık hizmeti ile ilişkili infeksiyonların yaklaşık yarısı kateter ilişkili üriner sistem infeksiyonu (% 47.1), % 35.7’si kan dolaşımı infeksiyonu ve % 17.1’i ventilatör ilişkili pnömoni olarak tespit edilmiştir. Sürveyans çalışmaları sonucu her merkezin mikroorganizma dağılımı ve direnç durumlarını belirleyerek bu doğrultuda akılcı antibiyotik kullanımına önem vermesi, dirençli mikroorganizmalarla mücadelede başarı sağlayacaktır.
The aim of the present study was to evaluation the health-care associated infections developing in intensive care unit of our hospital in 2011. Based on the patient, active, prospective surveillance is made in intensive care unit. Centers for Disease Control and Prevention (CDC) diagnostic criteria were used for nosocomial infection diagnosis. Infectious agents isolated were identified by conventional methods and VITEK2 Compact System (bioMérieux, France). According to the standards of Clinical and Laboratory Standards Institute (CLSI); antibiotics susceptibility tests were performed by using disc diffusion method. During the study, 415 patients were observed on 3654 patients’ days in intensive care unit. This period, 70 nosocomial infections were described. Nosocomial infection rate of 16.9 %, nosocomial infection incidence density was calculated as 19.2 per thousand. Totally 71 microorganisms were isolated; 36 of them were determined as Gram negative bacteria while 17 were Gram positive bacteria and 18 were Candida spp. Urinary tract catheter-associated infection (47.1 %) was approximately half of the health-care associated infections, followed by bloodstream infections (35.7 %), and ventilator associated pneumonia (17.1 %). As a result of surveillance studies each center determining the distribution of microorganisms and resistance status give importance to the rational use of antibiotics in this direction will ensure success in the fight against with resistant microorganisms.
The aim of the present study was to evaluation the health-care associated infections developing in intensive care unit of our hospital in 2011. Based on the patient, active, prospective surveillance is made in intensive care unit. Centers for Disease Control and Prevention (CDC) diagnostic criteria were used for nosocomial infection diagnosis. Infectious agents isolated were identified by conventional methods and VITEK2 Compact System (bioMérieux, France). According to the standards of Clinical and Laboratory Standards Institute (CLSI); antibiotics susceptibility tests were performed by using disc diffusion method. During the study, 415 patients were observed on 3654 patients’ days in intensive care unit. This period, 70 nosocomial infections were described. Nosocomial infection rate of 16.9 %, nosocomial infection incidence density was calculated as 19.2 per thousand. Totally 71 microorganisms were isolated; 36 of them were determined as Gram negative bacteria while 17 were Gram positive bacteria and 18 were Candida spp. Urinary tract catheter-associated infection (47.1 %) was approximately half of the health-care associated infections, followed by bloodstream infections (35.7 %), and ventilator associated pneumonia (17.1 %). As a result of surveillance studies each center determining the distribution of microorganisms and resistance status give importance to the rational use of antibiotics in this direction will ensure success in the fight against with resistant microorganisms.
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Farmakoloji ve Eczacılık
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26
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3
