Synthesis, crystal structure and antifungal/antibacterial activity of some novel highly functionalized benzoylaminocarbothioyl pyrrolidines

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dc.contributor.authorDöndaş, Hacı Ali
dc.contributor.authorNural, Yahya
dc.contributor.authorDuran, Nizami
dc.contributor.authorKılner, Colin
dc.date.accessioned2019-07-16T15:48:24Z
dc.date.available2019-07-16T15:48:24Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractA series of novel highly functionalized benzoylaminocarbothioyl pyrrolidines were prepared from benzoylisothiocyanate and substituted pyrrolidines in excellent yield. The crystal structure of the novel 1- benzoylaminocarbothioyl-5-(naphthyl)-pyrrolidine-2,3,4-tricarboxylicacid trimethyl ester (3a) was determined by X-ray crystal structure analysis. The synthesized compounds were characterized and screened for their in vitro antibacterial and antifungal activities and toxicity. The prepared compounds were tested against the standard strains: Escherichia coli (ATCC 25922), Enterobacter cloacae (ATCC 13047), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 29213) and Staphylococcus epidermidis (ATCC 12228) and the yeasts Candida albicans (ATCC 90028), Candida krusei (ATCC 6258), Candida parapsilosis (ATCC 22019), Candida tropicalis (ATCC 22019) and Candida glabrata (ATCC 32554).en_US
dc.description.abstracten_US
dc.identifier.endpage583en_US
dc.identifier.issn1300-0527
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-33845305764en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage573en_US
dc.identifier.urihttps://trdizin.gov.tr/publication/paper/detail/TmpRek1UZzQ=
dc.identifier.urihttps://hdl.handle.net/20.500.12483/1030
dc.identifier.volume30en_US
dc.identifier.wosWOS:000243366000005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMühendisliken_US
dc.subjectKimyaen_US
dc.titleSynthesis, crystal structure and antifungal/antibacterial activity of some novel highly functionalized benzoylaminocarbothioyl pyrrolidinesen_US
dc.typeArticleen_US

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